ID F4KHQ8_ARATH Unreviewed; 733 AA. AC F4KHQ8; DT 28-JUN-2011, integrated into UniProtKB/TrEMBL. DT 28-JUN-2011, sequence version 1. DT 11-NOV-2015, entry version 34. DE SubName: Full=Neutral/alkaline non-lysosomal ceramidase {ECO:0000313|EMBL:AED97126.1}; GN OrderedLocusNames=At5g58980 {ECO:0000313|EMBL:AED97126.1, GN ECO:0000313|TAIR:AT5G58980}; OS Arabidopsis thaliana (Mouse-ear cress). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; OC Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; OC Arabidopsis. OX NCBI_TaxID=3702 {ECO:0000313|EMBL:AED97126.1, ECO:0000313|Proteomes:UP000006548}; RN [1] {ECO:0000313|EMBL:AED97126.1, ECO:0000313|Proteomes:UP000006548} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548}; RX PubMed=11130714; DOI=10.1038/35048507; RG Kazusa DNA Research Institute; RG Cold Spring Harbor and Washington University in St Louis Sequencing Consortium; RG European Union Arabidopsis Genome Sequencing Consortium; RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E., RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., RA Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., RA Nakazaki N., Naruo K., Okumura S., Shinpo S., Takeuchi C., Wada T., RA Watanabe A., Yamada M., Yasuda M., Sato S., de la Bastide M., RA Huang E., Spiegel L., Gnoj L., O'Shaughnessy A., Preston R., RA Habermann K., Murray J., Johnson D., Rohlfing T., Nelson J., RA Stoneking T., Pepin K., Spieth J., Sekhon M., Armstrong J., Becker M., RA Belter E., Cordum H., Cordes M., Courtney L., Courtney W., Dante M., RA Du H., Edwards J., Fryman J., Haakensen B., Lamar E., Latreille P., RA Leonard S., Meyer R., Mulvaney E., Ozersky P., Riley A., Strowmatt C., RA Wagner-McPherson C., Wollam A., Yoakum M., Bell M., Dedhia N., RA Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D., Baker J., RA Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A., RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I., RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T., RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., RA Langham S.-A., McCullagh B., Robben J., Grymonprez B., Zimmermann W., RA Ramsperger U., Wedler H., Balke K., Wedler E., Peters S., RA van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., RA Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S., Hempel S., RA Feldpausch M., Lamberth S., Villarroel R., Gielen J., Ardiles W., RA Bents O., Lemcke K., Kolesov G., Mayer K.F.X., Rudd S., Schoof H., RA Schueller C., Zaccaria P., Mewes H.-W., Bevan M., Fransz P.F.; RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis RT thaliana."; RL Nature 408:823-826(2000). RN [2] {ECO:0000313|Proteomes:UP000006548} RP GENOME REANNOTATION. RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548}; RG The Arabidopsis Information Resource (TAIR); RL Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP002688; AED97126.1; -; Genomic_DNA. DR RefSeq; NP_200706.1; NM_125288.4. DR UniGene; At.29250; -. DR ProteinModelPortal; F4KHQ8; -. DR SMR; F4KHQ8; 27-732. DR STRING; 3702.AT5G58980.1; -. DR PaxDb; F4KHQ8; -. DR PRIDE; F4KHQ8; -. DR EnsemblPlants; AT5G58980.1; AT5G58980.1; AT5G58980. DR GeneID; 836015; -. DR KEGG; ath:AT5G58980; -. DR TAIR; AT5G58980; -. DR eggNOG; KOG2232; Eukaryota. DR eggNOG; ENOG410XQWE; LUCA. DR InParanoid; F4KHQ8; -. DR KO; K12349; -. DR OMA; STATIEW; -. DR Reactome; R-ATH-1660662; Glycosphingolipid metabolism. DR Proteomes; UP000006548; Chromosome 5. DR GO; GO:0005576; C:extracellular region; IBA:GO_Central. DR GO; GO:0017040; F:ceramidase activity; IBA:GO_Central. DR GO; GO:0046514; P:ceramide catabolic process; IBA:GO_Central. DR GO; GO:0042759; P:long-chain fatty acid biosynthetic process; IBA:GO_Central. DR GO; GO:0046512; P:sphingosine biosynthetic process; IBA:GO_Central. DR InterPro; IPR006823; Ceramidase_alk. DR InterPro; IPR031331; NEUT/ALK_ceramidase_C. DR InterPro; IPR031329; NEUT/ALK_ceramidase_N. DR PANTHER; PTHR12670; PTHR12670; 2. DR Pfam; PF04734; Ceramidase_alk; 1. DR Pfam; PF17048; Ceramidse_alk_C; 1. PE 4: Predicted; KW Complete proteome {ECO:0000313|Proteomes:UP000006548}; KW Reference proteome {ECO:0000313|Proteomes:UP000006548}; KW Signal {ECO:0000256|SAM:SignalP}. FT SIGNAL 1 25 {ECO:0000256|SAM:SignalP}. FT CHAIN 26 733 {ECO:0000256|SAM:SignalP}. FT /FTId=PRO_5003311651. SQ SEQUENCE 733 AA; 81838 MW; 4E00C150E5FCEED9 CRC64; MTRWSMSMHC TLFLLFLLRL TCIFSDSDYL MGLGSYDITG PAADVNMMGY ANMEQVASGV HFRLRARAFI VAEPYKKRIA FVNLDAGMAS QLVTIKVIER LKQRYGELYT EENVAISGTH THAGPGGYLQ YILYLVTSLG FVHQSFNALV DGIEQSIIQA HENLRPGSIL INKGELLDAG VNRSPSAYLN NPAHERSKYE YDVDKEMTLV KFVDDQWGPV ARIMEDWFER ENGCRSVDVE SPRRVSSIIS DPYDQDLMEM ASSLLSTGGK TVTRMSSVAR RVRSRFRHAD KPRFVSAFCQ TNCGDVSPNV LGAFCIDTGL PCEFNQSTCG GKNEQCYGRG PGYPDEFEST RIIGERQFKK AADLFTKASE EIQGKVDYRH AYVDFSQLEV TINGQNGGSE VVKTCPAAMG FGFAAGTTDG PGAFDFKQGD DQGNPFWRLV RNLLKNPTEE QVRCQRPKPI LLDTGEMKQP YDWAPSILPV QILRIGQLVI LCVPGEFTTM AGRRLRDAVK TVLKEGSNGR EFSVVIAGLT NSYSQYIATF EEYQVQRYEG ASTLYGPHTL SGYIQEFKKL ANDLLSAQTT DPGPQPPDLL HKQISLLTPV VADMTPIGTA FGDVTSDVPR LSKFRKGADI VRVQFRSANP RNDLMTEGTF ALVERWLEGR ETWVPVYDDD DFCLRFKWSR PFKLSTQSTA TIEWRIPETA SPGVYRITHF GSAKTPISSI HHFSGSSSAF VVY //