ID F4IS57_ARATH Unreviewed; 479 AA. AC F4IS57; DT 28-JUN-2011, integrated into UniProtKB/TrEMBL. DT 28-JUN-2011, sequence version 1. DT 09-DEC-2015, entry version 40. DE SubName: Full=Integrin-linked protein kinase-like protein {ECO:0000313|EMBL:AEC10335.1}; GN OrderedLocusNames=At2g43850 {ECO:0000313|EMBL:AEC10335.1, GN ECO:0000313|TAIR:AT2G43850}; OS Arabidopsis thaliana (Mouse-ear cress). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; OC Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; OC Arabidopsis. OX NCBI_TaxID=3702 {ECO:0000313|EMBL:AEC10335.1, ECO:0000313|Proteomes:UP000006548}; RN [1] {ECO:0000313|EMBL:AEC10335.1, ECO:0000313|Proteomes:UP000006548} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548}; RX PubMed=10617197; DOI=10.1038/45471; RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., RA Moffat K.S., Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., RA Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., RA Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., RA Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., RA Venter J.C.; RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis RT thaliana."; RL Nature 402:761-768(1999). RN [2] {ECO:0000313|Proteomes:UP000006548} RP GENOME REANNOTATION. RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548}; RG The Arabidopsis Information Resource (TAIR); RL Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases. CC -!- SIMILARITY: Contains 3 ANK repeats. CC {ECO:0000256|RuleBase:RU003321}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP002685; AEC10335.1; -; Genomic_DNA. DR RefSeq; NP_973683.1; NM_201954.1. DR UniGene; At.36834; -. DR UniGene; At.50136; -. DR ProteinModelPortal; F4IS57; -. DR SMR; F4IS57; 42-461. DR STRING; 3702.AT2G43850.1; -. DR PaxDb; F4IS57; -. DR PRIDE; F4IS57; -. DR EnsemblPlants; AT2G43850.2; AT2G43850.2; AT2G43850. DR GeneID; 818989; -. DR TAIR; AT2G43850; -. DR eggNOG; COG0515; LUCA. DR eggNOG; KOG0192; Eukaryota. DR OMA; CDQEAIN; -. DR Reactome; R-ATH-450302; activated TAK1 mediates p38 MAPK activation. DR Reactome; R-ATH-450321; JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1. DR Proteomes; UP000006548; Chromosome 2. DR ExpressionAtlas; F4IS57; baseline and differential. DR GO; GO:0005524; F:ATP binding; IEA:InterPro. DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro. DR GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW. DR Gene3D; 1.25.40.20; -; 1. DR InterPro; IPR002110; Ankyrin_rpt. DR InterPro; IPR020683; Ankyrin_rpt-contain_dom. DR InterPro; IPR011009; Kinase-like_dom. DR InterPro; IPR000719; Prot_kinase_dom. DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom. DR InterPro; IPR008271; Ser/Thr_kinase_AS. DR Pfam; PF07714; Pkinase_Tyr; 1. DR SMART; SM00248; ANK; 3. DR SUPFAM; SSF48403; SSF48403; 1. DR SUPFAM; SSF56112; SSF56112; 1. DR PROSITE; PS50297; ANK_REP_REGION; 1. DR PROSITE; PS50088; ANK_REPEAT; 1. DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1. DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1. PE 4: Predicted; KW ANK repeat {ECO:0000256|RuleBase:RU003321}; KW Complete proteome {ECO:0000313|Proteomes:UP000006548}; KW Integrin {ECO:0000313|EMBL:AEC10335.1}; KW Kinase {ECO:0000313|EMBL:AEC10335.1}; KW Reference proteome {ECO:0000313|Proteomes:UP000006548}; KW Transferase {ECO:0000313|EMBL:AEC10335.1}. FT DOMAIN 77 175 ANK_REP_REGION. {ECO:0000259|PROSITE: FT PS50297}. FT DOMAIN 194 461 Protein kinase. {ECO:0000259|PROSITE: FT PS50011}. SQ SEQUENCE 479 AA; 54445 MW; BA1D3F1D6188B052 CRC64; MENITAQLKR GISRQFSTGS IRRTLSRQFT RQSSLDPRRT NMRFSFGRQS SLDPIRRSPD SSKSDDEPHM SVPENLDSTM QLLFMASKGD VRGIEELLDE GIDVNSIDLD GRTALHIAAC EGHLGVVKAL LSRRANIDAR DRWGSTAAAD AKYYGNLDVY NLLKARGAKV PKTRKTPMTV SNPREVPEYE LNPLEVQVRK SDGISKASYQ VAKWNGTRVS VKILDKDSYS DPERINAFRH ELTLLEKVRH PNVIQFVGAV TQNIPMMIVV EYNPKGDLSV YLQKKGRLSP SKALRFALDI ARGMNYLHEC KPDPIIHCDL KPKNILLDRG GQLKISGFGM IRLSKISQDK AKVANHKAHI DLSNYYIAPE VYKDEIFDLR VDAHSFGVIL YEITEGVPVF HPRPPEEVAR MMCLEGKRPV FKTKSRSYPP DIKELIEKCW HPEAGIRPTF SEIIIRLDKI VANCSKQGWW KDTFKFPWK //