ID F4IS56_ARATH Unreviewed; 479 AA. AC F4IS56; DT 28-JUN-2011, integrated into UniProtKB/TrEMBL. DT 28-JUN-2011, sequence version 1. DT 18-JAN-2017, entry version 49. DE SubName: Full=Integrin-linked protein kinase-like protein {ECO:0000313|EMBL:AEC10334.1}; DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:OAP10938.1}; GN OrderedLocusNames=At2g43850 {ECO:0000313|EMBL:AEC10334.1, GN ECO:0000313|TAIR:AT2G43850}, AXX17_At2g41370 GN {ECO:0000313|EMBL:OAP10938.1}; OS Arabidopsis thaliana (Mouse-ear cress). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; OC Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; OC Arabidopsis. OX NCBI_TaxID=3702 {ECO:0000313|EMBL:AEC10334.1, ECO:0000313|Proteomes:UP000006548}; RN [1] {ECO:0000313|EMBL:AEC10334.1, ECO:0000313|Proteomes:UP000006548} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548}; RX PubMed=10617197; DOI=10.1038/45471; RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., RA Moffat K.S., Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., RA Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., RA Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., RA Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., RA Venter J.C.; RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis RT thaliana."; RL Nature 402:761-768(1999). RN [2] {ECO:0000313|EMBL:AEC10334.1} RP NUCLEOTIDE SEQUENCE. RG TAIR; RA Swarbreck D., Lamesch P., Wilks C., Huala E.; RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases. RN [3] {ECO:0000313|Proteomes:UP000006548} RP GENOME REANNOTATION. RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548}; RG The Arabidopsis Information Resource (TAIR); RL Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases. RN [4] {ECO:0000313|EMBL:OAP10938.1} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC TISSUE=Leaf {ECO:0000313|EMBL:OAP10938.1}; RA Zapata L., Schneeberger K., Ossowski S.; RT "Full-length assembly of Arabidopsis thaliana Ler reveals the RT complement of translocations and inversions."; RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases. CC -!- SIMILARITY: Contains 1 ANK repeat. {ECO:0000256|PROSITE- CC ProRule:PRU00023, ECO:0000256|RuleBase:RU003321}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP002685; AEC10334.1; -; Genomic_DNA. DR EMBL; LUHQ01000002; OAP10938.1; -; Genomic_DNA. DR RefSeq; NP_181913.3; NM_129947.4. DR UniGene; At.36834; -. DR UniGene; At.50136; -. DR SMR; F4IS56; -. DR STRING; 3702.AT2G43850.1; -. DR PaxDb; F4IS56; -. DR EnsemblPlants; AT2G43850.1; AT2G43850.1; AT2G43850. DR GeneID; 818989; -. DR Gramene; AT2G43850.1; AT2G43850.1; AT2G43850. DR KEGG; ath:AT2G43850; -. DR TAIR; AT2G43850; -. DR eggNOG; KOG0192; Eukaryota. DR eggNOG; COG0515; LUCA. DR InParanoid; F4IS56; -. DR Reactome; R-ATH-450302; activated TAK1 mediates p38 MAPK activation. DR Reactome; R-ATH-450321; JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1. DR Proteomes; UP000006548; Chromosome 2. DR ExpressionAtlas; F4IS56; baseline and differential. DR GO; GO:0009898; C:cytoplasmic side of plasma membrane; IDA:TAIR. DR GO; GO:0005783; C:endoplasmic reticulum; IDA:TAIR. DR GO; GO:0005524; F:ATP binding; IEA:InterPro. DR GO; GO:0004672; F:protein kinase activity; IMP:TAIR. DR GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR. DR GO; GO:0004712; F:protein serine/threonine/tyrosine kinase activity; ISS:TAIR. DR GO; GO:0045087; P:innate immune response; IDA:TAIR. DR GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW. DR GO; GO:0046777; P:protein autophosphorylation; IDA:TAIR. DR GO; GO:0006970; P:response to osmotic stress; IMP:TAIR. DR Gene3D; 1.25.40.20; -; 1. DR InterPro; IPR002110; Ankyrin_rpt. DR InterPro; IPR020683; Ankyrin_rpt-contain_dom. DR InterPro; IPR011009; Kinase-like_dom. DR InterPro; IPR000719; Prot_kinase_dom. DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom. DR InterPro; IPR008271; Ser/Thr_kinase_AS. DR Pfam; PF12796; Ank_2; 1. DR Pfam; PF07714; Pkinase_Tyr; 1. DR SMART; SM00248; ANK; 3. DR SMART; SM00220; S_TKc; 1. DR SUPFAM; SSF48403; SSF48403; 1. DR SUPFAM; SSF56112; SSF56112; 1. DR PROSITE; PS50297; ANK_REP_REGION; 1. DR PROSITE; PS50088; ANK_REPEAT; 1. DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1. DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1. PE 4: Predicted; KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023, KW ECO:0000256|RuleBase:RU003321}; KW Complete proteome {ECO:0000313|Proteomes:UP000006548}; KW Integrin {ECO:0000313|EMBL:AEC10334.1}; KW Kinase {ECO:0000313|EMBL:AEC10334.1}; KW Reference proteome {ECO:0000313|Proteomes:UP000006548}; KW Transferase {ECO:0000313|EMBL:AEC10334.1}. FT DOMAIN 77 175 ANK_REP_REGION. {ECO:0000259|PROSITE: FT PS50297}. FT REPEAT 110 142 ANK. {ECO:0000256|PROSITE-ProRule: FT PRU00023}. FT DOMAIN 194 461 Protein kinase. {ECO:0000259|PROSITE: FT PS50011}. SQ SEQUENCE 479 AA; 54415 MW; 2D4220B043E1F657 CRC64; MENITAQLKR GISRQFSTGS IRRTLSRQFT RQSSLDPRRT NMRFSFGRQS SLDPIRRSPD SSKSDDEPHM SVPENLDSTM QLLFMASKGD VRGIEELLDE GIDVNSIDLD GRTALHIAAC EGHLGVVKAL LSRRANIDAR DRWGSTAAAD AKYYGNLDVY NLLKARGAKV PKTRKTPMTV SNPREVPEYE LNPLEVQVRK SDGISKGAYQ VAKWNGTRVS VKILDKDSYS DPERINAFRH ELTLLEKVRH PNVIQFVGAV TQNIPMMIVV EYNPKGDLSV YLQKKGRLSP SKALRFALDI ARGMNYLHEC KPDPIIHCDL KPKNILLDRG GQLKISGFGM IRLSKISQDK AKVANHKAHI DLSNYYIAPE VYKDEIFDLR VDAHSFGVIL YEITEGVPVF HPRPPEEVAR MMCLEGKRPV FKTKSRSYPP DIKELIEKCW HPEAGIRPTF SEIIIRLDKI VANCSKQGWW KDTFKFPWK //