ID F2CCR8_STRSA Unreviewed; 124 AA. AC F2CCR8; DT 31-MAY-2011, integrated into UniProtKB/TrEMBL. DT 31-MAY-2011, sequence version 1. DT 16-APR-2014, entry version 13. DE RecName: Full=Putative fluoride ion transporter CrcB; GN Name=crcB2; Synonyms=crcB; ORFNames=HMPREF9391_0548; OS Streptococcus sanguinis SK408. OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; OC Streptococcus. OX NCBI_TaxID=888818; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=SK408; RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., RA Zhang L., Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., RA Korchina V., Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., RA Nguyen N., Okwuonu G., Ongeri F., Pham C., Simmons D., RA Wilczek-Boney K., Hale W., Jakkamsetti A., Pham P., Ruth R., RA San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C., Zhu D., Lee S., RA Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S., Hirani K., RA Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S., RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L., RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P., RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K., RA Petrosino J., Highlander S., Gibbs R.; RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Important for reducing fluoride concentration in the CC cell, thus reducing its toxicity (By similarity). CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein CC (By similarity). CC -!- SIMILARITY: Belongs to the CrcB (TC 9.B.71) family. CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AFBE01000002; EGF19828.1; -; Genomic_DNA. DR EnsemblBacteria; EGF19828; EGF19828; HMPREF9391_0548. DR PATRIC; 53633832; VBIStrSan170070_0532. DR GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-HAMAP. DR GO; GO:0015103; F:inorganic anion transmembrane transporter activity; IEA:UniProtKB-HAMAP. DR HAMAP; MF_00454; CrcB; 1. DR InterPro; IPR003691; CrcB. DR Pfam; PF02537; CRCB; 1. PE 3: Inferred from homology; KW Cell membrane; Membrane; Transmembrane; Transmembrane helix; KW Transport. FT TRANSMEM 10 30 Helical; (By similarity). FT TRANSMEM 33 53 Helical; (By similarity). FT TRANSMEM 66 86 Helical; (By similarity). FT TRANSMEM 98 118 Helical; (By similarity). SQ SEQUENCE 124 AA; 13260 MW; 4D53253598957D72 CRC64; MKEVQNSIAV ALSAMVGGWL RYQIALLLVV ADSFPLGTLL VNYLGTFLLV YIIKGYLSSK VKSQRLILAL STGFCGGLTT FSGLLLDSIK LADSGRYMEL LIYLVLSVGG GLAIALWAGK QVKS //