ID F1QAA7_DANRE Unreviewed; 698 AA. AC F1QAA7; DT 03-MAY-2011, integrated into UniProtKB/TrEMBL. DT 20-JUN-2018, sequence version 3. DT 18-JUL-2018, entry version 59. DE SubName: Full=Acyl-CoA synthetase short chain family member 2 {ECO:0000313|Ensembl:ENSDARP00000112054}; GN Name=acss2 {ECO:0000313|Ensembl:ENSDARP00000112054, GN ECO:0000313|ZFIN:ZDB-GENE-040718-388}; OS Danio rerio (Zebrafish) (Brachydanio rerio). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; OC Cyprinidae; Danio. OX NCBI_TaxID=7955 {ECO:0000313|Ensembl:ENSDARP00000112054, ECO:0000313|Proteomes:UP000000437}; RN [1] {ECO:0000313|Ensembl:ENSDARP00000112054} RP IDENTIFICATION. RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000112054}; RG Ensembl; RL Submitted (JUL-2011) to UniProtKB. RN [2] {ECO:0000313|Ensembl:ENSDARP00000112054, ECO:0000313|Proteomes:UP000000437} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000112054, RC ECO:0000313|Proteomes:UP000000437}; RX PubMed=23594743; DOI=10.1038/nature12111; RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., RA Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., RA McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., RA Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T., RA Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., RA Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., RA Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., RA Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G., RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P., RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., RA Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., RA Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., RA Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., RA Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., RA Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., RA Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., RA Murnane C., Gray E., Humphries M., Sycamore N., Barker D., RA Saunders D., Wallis J., Babbage A., Hammond S., RA Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., RA Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., RA Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., RA Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., RA Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., RA Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., RA Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., RA Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., RA Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., RA Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., RA Stemple D.L.; RT "The zebrafish reference genome sequence and its relationship to the RT human genome."; RL Nature 496:498-503(2013). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CT027560; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; CU137717; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR RefSeq; NP_001315282.1; NM_001328353.1. DR ProteinModelPortal; F1QAA7; -. DR STRING; 7955.ENSDARP00000112054; -. DR PaxDb; F1QAA7; -. DR PRIDE; F1QAA7; -. DR Ensembl; ENSDART00000125122; ENSDARP00000112054; ENSDARG00000037781. DR GeneID; 436914; -. DR ZFIN; ZDB-GENE-040718-388; acss2. DR eggNOG; KOG1175; Eukaryota. DR eggNOG; COG0365; LUCA. DR GeneTree; ENSGT00760000119178; -. DR InParanoid; F1QAA7; -. DR OMA; DHWWHDL; -. DR OrthoDB; EOG091G039C; -. DR TreeFam; TF300417; -. DR Reactome; R-DRE-2151201; Transcriptional activation of mitochondrial biogenesis. DR Reactome; R-DRE-71384; Ethanol oxidation. DR Proteomes; UP000000437; Chromosome 23. DR Bgee; ENSDARG00000037781; -. DR ExpressionAtlas; F1QAA7; baseline and differential. DR GO; GO:0003987; F:acetate-CoA ligase activity; IEA:InterPro. DR GO; GO:0016208; F:AMP binding; IEA:InterPro. DR GO; GO:0019427; P:acetyl-CoA biosynthetic process from acetate; IEA:InterPro. DR CDD; cd05966; ACS; 1. DR InterPro; IPR011904; Ac_CoA_lig. DR InterPro; IPR032387; ACAS_N. DR InterPro; IPR025110; AMP-bd_C. DR InterPro; IPR020845; AMP-binding_CS. DR InterPro; IPR000873; AMP-dep_Synth/Lig. DR Pfam; PF16177; ACAS_N; 1. DR Pfam; PF00501; AMP-binding; 1. DR Pfam; PF13193; AMP-binding_C; 1. DR PROSITE; PS00455; AMP_BINDING; 1. PE 1: Evidence at protein level; KW Complete proteome {ECO:0000313|Proteomes:UP000000437}; KW Proteomics identification {ECO:0000213|PeptideAtlas:F1QAA7}; KW Reference proteome {ECO:0000313|Proteomes:UP000000437}. FT DOMAIN 30 90 ACAS_N. {ECO:0000259|Pfam:PF16177}. FT DOMAIN 98 571 AMP-binding. {ECO:0000259|Pfam:PF00501}. FT DOMAIN 580 658 AMP-binding_C. {ECO:0000259|Pfam: FT PF13193}. SQ SEQUENCE 698 AA; 78599 MW; 7FAA30766BBF8BB2 CRC64; MIPEKAPGGD VLHAPGDLKK EAHIPSFEKY KELYIKSVES PEEFWADVAK DFFWKTKYTG KFLDYNFDVT KGEIYIKCME GATTNICYNV LDRNVHERKL GDRVAFYWEG NEPGDEKTVT YRELLQQVCK FANVLKSQGV KKGDRVSIYM PMVVELVVAM LACARIGAVH SIVFAGFSSE SLCERIMDSQ CCLLITADGF YRGDKLINLK LIADEALKKC RDKSFPVEKC IMLKHLTKED EASSGSLSPP AKRACPDLQQ EKQKERVRKV RPPPQVPWNP EVDMCWHSLI GGASEECEPV WCDSEDPLFI LYTSGSTGKP KGVLHTVSGY MLYTASTFKM VFDYHSDDVY WCTADIGWIT GHSYITYGPL ANGATSVLFE GLPTYPDVSR MWEIVDKYHV SKFYTAPTAI RLLMKYGSDP VHKYKRTSLK ILGTVGEPIN PEAWQWYYNV VGEKRCPVVD TFWQTETGGH VMTPLPAATP MKPGSATFPF FGVVPAILNE SGEELEGPSE GYLVFKQPWP GVMRTVYGNH LRFETTYFKK FPGYYVTGDG CRRDKDGYYW ITGRIDDMLN VSGHLLSTAE VESALVEHEA VAEAAVVGRP HPVKGESLYC FVTLNDGINY NQKLEAELKK QVREKIGAIA TPDYIQNAPG LPKTRSGKIM RRVLRKIACN ERDLGDVSTL ADSSVIEHLF ENRCYTAV //