ID F1QAA7_DANRE Unreviewed; 700 AA. AC F1QAA7; DT 03-MAY-2011, integrated into UniProtKB/TrEMBL. DT 22-NOV-2017, sequence version 2. DT 23-MAY-2018, entry version 57. DE SubName: Full=Acyl-CoA synthetase short chain family member 2 {ECO:0000313|Ensembl:ENSDARP00000112054}; GN Name=acss2 {ECO:0000313|Ensembl:ENSDARP00000112054, GN ECO:0000313|ZFIN:ZDB-GENE-040718-388}; OS Danio rerio (Zebrafish) (Brachydanio rerio). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; OC Cyprinidae; Danio. OX NCBI_TaxID=7955 {ECO:0000313|Ensembl:ENSDARP00000112054, ECO:0000313|Proteomes:UP000000437}; RN [1] {ECO:0000313|Ensembl:ENSDARP00000112054} RP IDENTIFICATION. RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000112054}; RG Ensembl; RL Submitted (JUL-2011) to UniProtKB. RN [2] {ECO:0000313|Ensembl:ENSDARP00000112054, ECO:0000313|Proteomes:UP000000437} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000112054, RC ECO:0000313|Proteomes:UP000000437}; RX PubMed=23594743; DOI=10.1038/nature12111; RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., RA Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., RA McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., RA Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T., RA Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., RA Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., RA Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., RA Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G., RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P., RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., RA Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., RA Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., RA Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., RA Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., RA Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., RA Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., RA Murnane C., Gray E., Humphries M., Sycamore N., Barker D., RA Saunders D., Wallis J., Babbage A., Hammond S., RA Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., RA Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., RA Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., RA Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., RA Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., RA Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., RA Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., RA Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., RA Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., RA Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., RA Stemple D.L.; RT "The zebrafish reference genome sequence and its relationship to the RT human genome."; RL Nature 496:498-503(2013). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CT027560; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; CU137717; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR ProteinModelPortal; F1QAA7; -. DR STRING; 7955.ENSDARP00000112054; -. DR PaxDb; F1QAA7; -. DR PRIDE; F1QAA7; -. DR Ensembl; ENSDART00000125122; ENSDARP00000112054; ENSDARG00000037781. DR ZFIN; ZDB-GENE-040718-388; acss2. DR eggNOG; KOG1175; Eukaryota. DR eggNOG; COG0365; LUCA. DR GeneTree; ENSGT00760000119178; -. DR InParanoid; F1QAA7; -. DR OMA; DHWWHDL; -. DR OrthoDB; EOG091G039C; -. DR TreeFam; TF300417; -. DR Reactome; R-DRE-2151201; Transcriptional activation of mitochondrial biogenesis. DR Reactome; R-DRE-71384; Ethanol oxidation. DR Proteomes; UP000000437; Chromosome 23. DR Bgee; ENSDARG00000037781; -. DR ExpressionAtlas; F1QAA7; baseline and differential. DR GO; GO:0003987; F:acetate-CoA ligase activity; IEA:InterPro. DR GO; GO:0016208; F:AMP binding; IEA:InterPro. DR GO; GO:0019427; P:acetyl-CoA biosynthetic process from acetate; IEA:InterPro. DR CDD; cd05966; ACS; 1. DR InterPro; IPR011904; Ac_CoA_lig. DR InterPro; IPR032387; ACAS_N. DR InterPro; IPR025110; AMP-bd_C. DR InterPro; IPR020845; AMP-binding_CS. DR InterPro; IPR000873; AMP-dep_Synth/Lig. DR Pfam; PF16177; ACAS_N; 1. DR Pfam; PF00501; AMP-binding; 1. DR Pfam; PF13193; AMP-binding_C; 1. DR PROSITE; PS00455; AMP_BINDING; 1. PE 1: Evidence at protein level; KW Complete proteome {ECO:0000313|Proteomes:UP000000437}; KW Proteomics identification {ECO:0000213|PeptideAtlas:F1QAA7}; KW Reference proteome {ECO:0000313|Proteomes:UP000000437}. FT DOMAIN 32 92 ACAS_N. {ECO:0000259|Pfam:PF16177}. FT DOMAIN 100 573 AMP-binding. {ECO:0000259|Pfam:PF00501}. FT DOMAIN 582 660 AMP-binding_C. {ECO:0000259|Pfam: FT PF13193}. SQ SEQUENCE 700 AA; 78866 MW; 73C0DB9AE170A0FF CRC64; MILHCMHAPG GDVLHAPGDL KKEAHIPSFE KYKELYIKSV ESPEEFWADV AKDFFWKTKY TGKFLDYNFD VTKGEIYIKC MEGATTNICY NVLDRNVHER KLGDRVAFYW EGNEPGDEKT VTYRELLQQV CKFANVLKSQ GVKKGDRVSI YMPMVVELVV AMLACARIGA VHSIVFAGFS SESLCERIMD SQCCLLITAD GFYRGDKLIN LKLIADEALK KCRDKSFPVE KCIMLKHLTK EDEASSGSLS PPAKRACPDL QQEKQKERVR KVRPPPQVPW NPEVDMCWHS LIGGASEECE PVWCDSEDPL FILYTSGSTG KPKGVLHTVS GYMLYTASTF KMVFDYHSDD VYWCTADIGW ITGHSYITYG PLANGATSVL FEGLPTYPDV SRMWEIVDKY HVSKFYTAPT AIRLLMKYGS DPVHKYKRTS LKILGTVGEP INPEAWQWYY NVVGEKRCPV VDTFWQTETG GHVMTPLPAA TPMKPGSATF PFFGVVPAIL NESGEELEGP SEGYLVFKQP WPGVMRTVYG NHLRFETTYF KKFPGYYVTG DGCRRDKDGY YWITGRIDDM LNVSGHLLST AEVESALVEH EAVAEAAVVG RPHPVKGESL YCFVTLNDGI NYNQKLEAEL KKQVREKIGA IATPDYIQNA PGLPKTRSGK IMRRVLRKIA CNERDLGDVS TLADSSVIEH LFENRCYTAV //