ID F1MUZ9_BOVIN Unreviewed; 573 AA. AC F1MUZ9; DT 03-MAY-2011, integrated into UniProtKB/TrEMBL. DT 03-MAY-2011, sequence version 1. DT 26-FEB-2020, entry version 74. DE SubName: Full=60 kDa heat shock protein, mitochondrial {ECO:0000313|Ensembl:ENSBTAP00000016708}; GN Name=HSPD1 {ECO:0000313|Ensembl:ENSBTAP00000016708, GN ECO:0000313|VGNC:VGNC:49070}; OS Bos taurus (Bovine). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; OC Bovinae; Bos. OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000016708, ECO:0000313|Proteomes:UP000009136}; RN [1] {ECO:0000313|Ensembl:ENSBTAP00000016708} RP IDENTIFICATION. RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000016708}; RG Ensembl; RL Submitted (MAR-2016) to UniProtKB. RN [2] {ECO:0000313|Ensembl:ENSBTAP00000016708, ECO:0000313|Proteomes:UP000009136} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000016708, RC ECO:0000313|Proteomes:UP000009136}; RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A., RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C., RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.; RT "ARS-UCD1.2."; RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases. CC -!- SIMILARITY: Belongs to the chaperonin (HSP60) family. CC {ECO:0000256|RuleBase:RU000418}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR RefSeq; NP_001160080.1; NM_001166608.1. DR RefSeq; NP_001160081.1; NM_001166609.1. DR RefSeq; NP_001160082.1; NM_001166610.1. DR SMR; F1MUZ9; -. DR Ensembl; ENSBTAT00000016708; ENSBTAP00000016708; ENSBTAG00000012586. DR Ensembl; ENSBTAT00000064253; ENSBTAP00000055431; ENSBTAG00000012586. DR GeneID; 511913; -. DR KEGG; bta:511913; -. DR CTD; 3329; -. DR VGNC; VGNC:49070; HSPD1. DR eggNOG; KOG0356; Eukaryota. DR eggNOG; COG0459; LUCA. DR GeneTree; ENSGT00390000005727; -. DR HOGENOM; CLU_016503_3_0_1; -. DR KO; K04077; -. DR OMA; TDTDKME; -. DR OrthoDB; 415781at2759; -. DR TreeFam; TF300475; -. DR Proteomes; UP000009136; Chromosome 2. DR Bgee; ENSBTAG00000012586; Expressed in adult mammalian kidney and 9 other tissues. DR GO; GO:0005829; C:cytosol; IBA:GO_Central. DR GO; GO:0005524; F:ATP binding; IEA:InterPro. DR GO; GO:0051082; F:unfolded protein binding; IBA:GO_Central. DR GO; GO:0006458; P:'de novo' protein folding; IBA:GO_Central. DR GO; GO:0008637; P:apoptotic mitochondrial changes; IBA:GO_Central. DR GO; GO:0045041; P:protein import into mitochondrial intermembrane space; IBA:GO_Central. DR GO; GO:0042026; P:protein refolding; IEA:InterPro. DR GO; GO:0009409; P:response to cold; ISS:AgBase. DR GO; GO:0042110; P:T cell activation; IBA:GO_Central. DR CDD; cd03344; GroEL; 1. DR Gene3D; 1.10.560.10; -; 1. DR Gene3D; 3.30.260.10; -; 1. DR Gene3D; 3.50.7.10; -; 1. DR HAMAP; MF_00600; CH60; 1. DR InterPro; IPR018370; Chaperonin_Cpn60_CS. DR InterPro; IPR001844; Chaprnin_Cpn60. DR InterPro; IPR002423; Cpn60/TCP-1. DR InterPro; IPR027409; GroEL-like_apical_dom_sf. DR InterPro; IPR027413; GROEL-like_equatorial_sf. DR InterPro; IPR027410; TCP-1-like_intermed_sf. DR Pfam; PF00118; Cpn60_TCP1; 1. DR PRINTS; PR00298; CHAPERONIN60. DR SUPFAM; SSF48592; SSF48592; 1. DR SUPFAM; SSF52029; SSF52029; 1. DR SUPFAM; SSF54849; SSF54849; 1. DR TIGRFAMs; TIGR02348; GroEL; 1. DR PROSITE; PS00296; CHAPERONINS_CPN60; 1. PE 1: Evidence at protein level; KW Coiled coil {ECO:0000256|SAM:Coils}; KW Proteomics identification {ECO:0000213|PeptideAtlas:F1MUZ9}; KW Reference proteome {ECO:0000313|Proteomes:UP000009136}. FT COILED 364..384 FT /evidence="ECO:0000256|SAM:Coils" SQ SEQUENCE 573 AA; 60978 MW; A89C00A4C74010AE CRC64; MLRLPAVLRQ MRPVSRALAP HLTRAYAKDV KFGADARALM LQGVDLLADA VAVTMGPKGR TVIIEQSWGS PKVTKDGVTV AKSIDLKDKY KNIGAKLVQD VANNTNEEAG DGTTTATVLA RSIAKEGFEK ISKGANPVEI RRGVMLAVDA VIAELKKQSK PVTTPEEIAQ VATISANGDK EIGNIISDAM KKVGRKGVIT VKDGKTLNDE LEIIEGMKFD RGYISPYFIN TSKGQKCEFQ DAYVLLSEKK ISSVQSIVPA LEIANAHRKP LVIIAEDVDG EALSTLVLNR LKVGLQVVAV KAPGFGDNRK NQLKDMAIAT GGAVFGEEGL NLNLEDVQPH DLGKVGEVIV TKDDAMLLKG KGDKAQIEKR IQEIIEQLDI TTSEYEKEKL NERLAKLSDG VAVLKVGGTS DVEVNEKKDR VTDALNATRA AVEEGIVLGG GCALLRCIPA LESITPANED QKTGIEIIKK TLKIPAMTIA KNAGVEGSLI VEKIMQSSSE VGYDAMLGDF VNMVEKGIID PTKVVRTALL DAAGVASLLT TAEVVVTEIP KEEKDPGMGG MGGMGGGMGG GMF //