ID   F1MUZ9_BOVIN            Unreviewed;       573 AA.
AC   F1MUZ9;
DT   03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   03-MAY-2011, sequence version 1.
DT   11-JUL-2012, entry version 11.
DE   SubName: Full=Uncharacterized protein;
GN   Name=Bt.89909;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
OC   Pecora; Bovidae; Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hereford;
RX   PubMed=19390049; DOI=10.1126/science.1169588;
RG   The bovine genome sequencing and analysis consortium;
RT   "The genome sequence of taurine cattle: a window to ruminant biology
RT   and evolution.";
RL   Science 324:522-528(2009).
RN   [2]
RP   IDENTIFICATION.
RC   STRAIN=Hereford, and Hereford;
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the chaperonin (HSP60) family.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DAAA02005515; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   IPI; IPI01002905; -.
DR   RefSeq; NP_001160080.1; NM_001166608.1.
DR   RefSeq; NP_001160081.1; NM_001166609.1.
DR   RefSeq; NP_001160082.1; NM_001166610.1.
DR   UniGene; Bt.24270; -.
DR   Ensembl; ENSBTAT00000016708; ENSBTAP00000016708; ENSBTAG00000012586.
DR   Ensembl; ENSBTAT00000064253; ENSBTAP00000055431; ENSBTAG00000012586.
DR   GeneID; 511913; -.
DR   KEGG; bta:511913; -.
DR   CTD; 3329; -.
DR   GeneTree; ENSGT00390000005727; -.
DR   KO; K04077; -.
DR   OMA; VQSIIPA; -.
DR   NextBio; 20870158; -.
DR   GO; GO:0009986; C:cell surface; IEA:Compara.
DR   GO; GO:0005905; C:coated pit; IEA:Compara.
DR   GO; GO:0030135; C:coated vesicle; IEA:Compara.
DR   GO; GO:0019907; C:cyclin-dependent protein kinase activating kinase holoenzyme complex; IEA:Compara.
DR   GO; GO:0005829; C:cytosol; IEA:Compara.
DR   GO; GO:0005769; C:early endosome; IEA:Compara.
DR   GO; GO:0005615; C:extracellular space; IEA:Compara.
DR   GO; GO:0046696; C:lipopolysaccharide receptor complex; IEA:Compara.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:Compara.
DR   GO; GO:0044459; C:plasma membrane part; IEA:Compara.
DR   GO; GO:0030141; C:secretory granule; IEA:Compara.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0043498; F:cell surface binding; IEA:Compara.
DR   GO; GO:0001530; F:lipopolysaccharide binding; IEA:Compara.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Compara.
DR   GO; GO:0002368; P:B cell cytokine production; IEA:Compara.
DR   GO; GO:0042100; P:B cell proliferation; IEA:Compara.
DR   GO; GO:0048291; P:isotype switching to IgG isotypes; IEA:Compara.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; IEA:Compara.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Compara.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Compara.
DR   GO; GO:0032727; P:positive regulation of interferon-alpha production; IEA:Compara.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; IEA:Compara.
DR   GO; GO:0032733; P:positive regulation of interleukin-10 production; IEA:Compara.
DR   GO; GO:0032735; P:positive regulation of interleukin-12 production; IEA:Compara.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; IEA:Compara.
DR   GO; GO:0043032; P:positive regulation of macrophage activation; IEA:Compara.
DR   GO; GO:0050870; P:positive regulation of T cell activation; IEA:Compara.
DR   GO; GO:0002842; P:positive regulation of T cell mediated immune response to tumor cell; IEA:Compara.
DR   GO; GO:0042026; P:protein refolding; IEA:Compara.
DR   GO; GO:0050821; P:protein stabilization; IEA:Compara.
DR   GO; GO:0006986; P:response to unfolded protein; IEA:Compara.
DR   GO; GO:0042110; P:T cell activation; IEA:Compara.
DR   HAMAP; MF_00600; CH60; 1; -.
DR   InterPro; IPR018370; Chaperonin_Cpn60_CS.
DR   InterPro; IPR001844; Chaprnin_Cpn60.
DR   InterPro; IPR002423; Cpn60/TCP-1.
DR   PANTHER; PTHR11353; Cpn60/TCP-1; 1.
DR   Pfam; PF00118; Cpn60_TCP1; 1.
DR   PRINTS; PR00298; CHAPERONIN60.
DR   SUPFAM; SSF48592; GroEL-ATPase; 1.
DR   TIGRFAMs; TIGR02348; GroEL; 1.
DR   PROSITE; PS00296; CHAPERONINS_CPN60; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Complete proteome; Nucleotide-binding;
KW   Reference proteome.
SQ   SEQUENCE   573 AA;  60978 MW;  A89C00A4C74010AE CRC64;
     MLRLPAVLRQ MRPVSRALAP HLTRAYAKDV KFGADARALM LQGVDLLADA VAVTMGPKGR
     TVIIEQSWGS PKVTKDGVTV AKSIDLKDKY KNIGAKLVQD VANNTNEEAG DGTTTATVLA
     RSIAKEGFEK ISKGANPVEI RRGVMLAVDA VIAELKKQSK PVTTPEEIAQ VATISANGDK
     EIGNIISDAM KKVGRKGVIT VKDGKTLNDE LEIIEGMKFD RGYISPYFIN TSKGQKCEFQ
     DAYVLLSEKK ISSVQSIVPA LEIANAHRKP LVIIAEDVDG EALSTLVLNR LKVGLQVVAV
     KAPGFGDNRK NQLKDMAIAT GGAVFGEEGL NLNLEDVQPH DLGKVGEVIV TKDDAMLLKG
     KGDKAQIEKR IQEIIEQLDI TTSEYEKEKL NERLAKLSDG VAVLKVGGTS DVEVNEKKDR
     VTDALNATRA AVEEGIVLGG GCALLRCIPA LESITPANED QKTGIEIIKK TLKIPAMTIA
     KNAGVEGSLI VEKIMQSSSE VGYDAMLGDF VNMVEKGIID PTKVVRTALL DAAGVASLLT
     TAEVVVTEIP KEEKDPGMGG MGGMGGGMGG GMF
//