ID F1LP59_RAT Unreviewed; 958 AA. AC F1LP59; DT 03-MAY-2011, integrated into UniProtKB/TrEMBL. DT 03-APR-2013, sequence version 2. DT 27-MAY-2015, entry version 32. DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSRNOP00000005289}; GN Name=Rab3gap1 {ECO:0000313|RGD:1306487}; GN Synonyms=RGD1306487 {ECO:0000313|RGD:1306487}; OS Rattus norvegicus (Rat). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Rattus. OX NCBI_TaxID=10116 {ECO:0000313|Ensembl:ENSRNOP00000005289, ECO:0000313|Proteomes:UP000002494}; RN [1] {ECO:0000313|Ensembl:ENSRNOP00000005289, ECO:0000313|Proteomes:UP000002494} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000005289, RC ECO:0000313|Proteomes:UP000002494}; RX PubMed=15057822; DOI=10.1038/nature02426; RG Rat Genome Sequencing Project Consortium; RA Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., RA Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., RA Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., RA Morgan M., Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., RA Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., RA Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., RA Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., RA Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., RA Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., RA Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., RA Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., RA Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., RA Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., RA Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., RA Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., RA D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., RA Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., RA Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., RA Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., RA Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., RA Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., RA Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., RA Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., RA Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., RA Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., RA Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., RA Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., RA Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., RA Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., RA Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., RA Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., RA Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., RA Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., RA Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., RA Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., RA Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., RA Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., RA Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., RA Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., RA Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., RA Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., RA Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., RA Collins F.S.; RT "Genome sequence of the Brown Norway rat yields insights into RT mammalian evolution."; RL Nature 428:493-521(2004). RN [2] {ECO:0000313|Ensembl:ENSRNOP00000005289} RP IDENTIFICATION. RC STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000005289}; RG Ensembl; RL Submitted (JUL-2011) to UniProtKB. RN [3] {ECO:0000213|PubMed:22673903} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=22673903; RA Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., RA Lundby C., Olsen J.V.; RT "Quantitative maps of protein phosphorylation sites across 14 RT different rat organs and tissues."; RL Nat. Commun. 3:876-876(2012). CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. {ECO:0000313|Ensembl:ENSRNOP00000005289}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AABR06074522; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AABR06074523; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AABR06074524; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AABR06074525; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AABR06074526; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AABR06074527; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR PRIDE; F1LP59; -. DR Ensembl; ENSRNOT00000005289; ENSRNOP00000005289; ENSRNOG00000003953. DR RGD; 1306487; Rab3gap1. DR GeneTree; ENSGT00390000006705; -. DR OMA; PIQAPHW; -. DR OrthoDB; EOG783MTK; -. DR TreeFam; TF314500; -. DR NextBio; 35576025; -. DR Proteomes; UP000002494; Chromosome 13. DR GO; GO:0071782; C:endoplasmic reticulum tubular network; IEA:Ensembl. DR GO; GO:0070062; C:extracellular exosome; IEA:Ensembl. DR GO; GO:0043234; C:protein complex; IEA:Ensembl. DR GO; GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; IEA:Ensembl. DR GO; GO:0043010; P:camera-type eye development; IEA:Ensembl. DR GO; GO:0097051; P:establishment of protein localization to endoplasmic reticulum membrane; IEA:Ensembl. DR GO; GO:0060325; P:face morphogenesis; IEA:Ensembl. DR GO; GO:0021854; P:hypothalamus development; IEA:Ensembl. DR GO; GO:0034389; P:lipid particle organization; IEA:Ensembl. DR GO; GO:1903373; P:positive regulation of endoplasmic reticulum tubular network organization; IEA:Ensembl. DR GO; GO:1903233; P:regulation of calcium ion-dependent exocytosis of neurotransmitter; IEA:Ensembl. DR GO; GO:0060079; P:regulation of excitatory postsynaptic membrane potential; IEA:Ensembl. DR GO; GO:0048172; P:regulation of short-term neuronal synaptic plasticity; IEA:Ensembl. DR InterPro; IPR026147; Rab3-GAP_cat_su. DR PANTHER; PTHR21422; PTHR21422; 1. DR Pfam; PF13890; Rab3-GTPase_cat; 1. PE 1: Evidence at protein level; KW Complete proteome {ECO:0000313|Proteomes:UP000002494}; KW Proteomics identification {ECO:0000213|PeptideAtlas:F1LP59}; KW Reference proteome {ECO:0000313|Proteomes:UP000002494}. SQ SEQUENCE 958 AA; 107450 MW; B5AD397DEF14802F CRC64; MAADSEPESE VFEITDFTTA SEWERFISKV EEVLNDWKLI GHSLGKPLEK GIFTSGTWEE RADEISFADF RFSVTHHYLV QESPDKEGKD EESEDAIPQS MQDLLCMNND FPPRAHCLVR WYGLREFVVI APAAHSDAVL SESKCNLLLS SISIALGNTG CFSSITFHNF EMLLLKFLDH RLKHLHGIVF ACVGCPLTPL PPVSIAIRFT YVLQDWQQYF WPQQPPDIDA LVGGEVGGLE FGKLPFGACE DPISELHLAT TWPHLTEGII VDNDVYSDLD PVQAPHWSVR VRKADNPQCL LGDFVTEFLK ICRRKESTDE ILGRSTFEEE GRDVADITHA LSKLTEPAPV PIHKLSVSNM VHTAKKKIRK HRGEESPLNN DVLNTILLFL FPDAASEKPL DGTTSVDNSN PTAEAGDYTL YNQFKSAPSD SLTYKLALCL CMINFYHGGL KGVAHLWQEF VLEMRFRWEN NFLIPGLASG PPDLRCCLLH QKLQMLNCCI ERKKARDEGK KTSPSDSMTK AYPADAGKAG GQLGLDHLRD TEKEKGEAGK SWDSWSDSEE EFFECLSDAE DLRGNGQEST KKGGPKDMAP LKPEGRLHQH GKLTLLRNGE PLYIPVTQEP APMTEDLLEE QSEVLAKLGT SAEGAHLRAR MQSACLLSDM ESFKAANPGC CLEDFVRWYS PRDYIEEEVT DEKGNVVLKG ELSARMKIPS NMWVEAWETA KPVPARRQRR LFDDTREAEK VLHYLAMQKP ADLARHLLPC VIHAAVLKVK EEESLENIPS VKKIIKQIIA HSSKVLRFPS PEDKKLEEII LQITTVEAII ARARSLKAKF GTEKCEHEEE KEDLERFVSC LLEQPEVAVT GAGRGHAGRI IHKLFVNAQR AAAVALPEEE LKRSGCPEER RQTLVSDFPP PAGRELILRA TVPRPAPYSK ALPQRMYSVL TKEDFRLAGA FSSDTSFF //