ID F1LP59_RAT Unreviewed; 958 AA. AC F1LP59; DT 03-MAY-2011, integrated into UniProtKB/TrEMBL. DT 03-APR-2013, sequence version 2. DT 16-OCT-2013, entry version 19. DE SubName: Full=Rab3 GTPase-activating protein catalytic subunit; GN Name=RGD1306487; Synonyms=Rab3gap1; OS Rattus norvegicus (Rat). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Rattus. OX NCBI_TaxID=10116; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Brown Norway; RX PubMed=15057822; DOI=10.1038/nature02426; RG Rat Genome Sequencing Project Consortium; RA Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., RA Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., RA Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., RA Morgan M., Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., RA Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., RA Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., RA Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., RA Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., RA Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., RA Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., RA Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., RA Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., RA Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., RA Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., RA Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., RA D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., RA Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., RA Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., RA Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., RA Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., RA Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., RA Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., RA Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., RA Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., RA Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., RA Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., RA Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., RA Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., RA Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., RA Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., RA Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., RA Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., RA Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., RA Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., RA Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., RA Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., RA Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., RA Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., RA Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., RA Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., RA Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., RA Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., RA Collins F.S.; RT "Genome sequence of the Brown Norway rat yields insights into RT mammalian evolution."; RL Nature 428:493-521(2004). RN [2] RP IDENTIFICATION. RC STRAIN=Brown Norway; RG Ensembl; RL Submitted (JUL-2011) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AABR06074522; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AABR06074523; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AABR06074524; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AABR06074525; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AABR06074526; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AABR06074527; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR IPI; IPI00371942; -. DR PRIDE; F1LP59; -. DR Ensembl; ENSRNOT00000005289; ENSRNOP00000005289; ENSRNOG00000003953. DR RGD; 1306487; RGD1306487. DR GeneTree; ENSGT00390000006705; -. DR OMA; AHLWQEF; -. DR NextBio; 35576025; -. DR ArrayExpress; F1LP59; -. DR GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro. DR GO; GO:0032851; P:positive regulation of Rab GTPase activity; IEA:GOC. DR InterPro; IPR026147; Rab3-GAP_cat_su. DR PANTHER; PTHR21422; PTHR21422; 1. DR Pfam; PF13890; Rab3-GTPase_cat; 1. PE 2: Evidence at transcript level; KW Complete proteome; Reference proteome. SQ SEQUENCE 958 AA; 107450 MW; B5AD397DEF14802F CRC64; MAADSEPESE VFEITDFTTA SEWERFISKV EEVLNDWKLI GHSLGKPLEK GIFTSGTWEE RADEISFADF RFSVTHHYLV QESPDKEGKD EESEDAIPQS MQDLLCMNND FPPRAHCLVR WYGLREFVVI APAAHSDAVL SESKCNLLLS SISIALGNTG CFSSITFHNF EMLLLKFLDH RLKHLHGIVF ACVGCPLTPL PPVSIAIRFT YVLQDWQQYF WPQQPPDIDA LVGGEVGGLE FGKLPFGACE DPISELHLAT TWPHLTEGII VDNDVYSDLD PVQAPHWSVR VRKADNPQCL LGDFVTEFLK ICRRKESTDE ILGRSTFEEE GRDVADITHA LSKLTEPAPV PIHKLSVSNM VHTAKKKIRK HRGEESPLNN DVLNTILLFL FPDAASEKPL DGTTSVDNSN PTAEAGDYTL YNQFKSAPSD SLTYKLALCL CMINFYHGGL KGVAHLWQEF VLEMRFRWEN NFLIPGLASG PPDLRCCLLH QKLQMLNCCI ERKKARDEGK KTSPSDSMTK AYPADAGKAG GQLGLDHLRD TEKEKGEAGK SWDSWSDSEE EFFECLSDAE DLRGNGQEST KKGGPKDMAP LKPEGRLHQH GKLTLLRNGE PLYIPVTQEP APMTEDLLEE QSEVLAKLGT SAEGAHLRAR MQSACLLSDM ESFKAANPGC CLEDFVRWYS PRDYIEEEVT DEKGNVVLKG ELSARMKIPS NMWVEAWETA KPVPARRQRR LFDDTREAEK VLHYLAMQKP ADLARHLLPC VIHAAVLKVK EEESLENIPS VKKIIKQIIA HSSKVLRFPS PEDKKLEEII LQITTVEAII ARARSLKAKF GTEKCEHEEE KEDLERFVSC LLEQPEVAVT GAGRGHAGRI IHKLFVNAQR AAAVALPEEE LKRSGCPEER RQTLVSDFPP PAGRELILRA TVPRPAPYSK ALPQRMYSVL TKEDFRLAGA FSSDTSFF //