ID   F1L0I3_ASCSU            Unreviewed;       524 AA.
AC   F1L0I3;
DT   03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   03-MAY-2011, sequence version 1.
DT   11-DEC-2013, entry version 17.
DE   SubName: Full=Tyrosine-protein kinase Fyn;
OS   Ascaris suum (Pig roundworm) (Ascaris lumbricoides).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Ascaridida;
OC   Ascaridoidea; Ascarididae; Ascaris.
OX   NCBI_TaxID=6253;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=21685128; DOI=10.1101/gr.121426.111;
RA   Wang J., Czech B., Crunk A., Wallace A., Mitreva M., Hannon G.J.,
RA   Davis R.E.;
RT   "Deep small RNA sequencing from the nematode Ascaris reveals
RT   conservation, functional diversification, and novel developmental
RT   profiles.";
RL   Genome Res. 21:1462-1477(2011).
CC   -!- CATALYTIC ACTIVITY: ATP + a [protein]-L-tyrosine = ADP + a
CC       [protein]-L-tyrosine phosphate.
CC   -!- SIMILARITY: Contains 1 SH2 domain.
CC   -!- SIMILARITY: Contains 1 SH3 domain.
CC   -!- SIMILARITY: Contains SH2 domain.
CC   -!- SIMILARITY: Contains SH3 domain.
CC   -!- SIMILARITY: Contains SHdomain.
CC   -!- SIMILARITY: Contains protein kinase domain.
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DR   EMBL; JI169079; ADY43637.1; -; mRNA.
DR   ProteinModelPortal; F1L0I3; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IEA:GOC.
DR   Gene3D; 3.30.505.10; -; 1.
DR   InterPro; IPR011009; Kinase-like_dom.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR017441; Protein_kinase_ATP_BS.
DR   InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR   InterPro; IPR000980; SH2.
DR   InterPro; IPR001452; SH3_domain.
DR   InterPro; IPR013315; Spectrin_alpha_SH3.
DR   InterPro; IPR008266; Tyr_kinase_AS.
DR   InterPro; IPR020635; Tyr_kinase_cat_dom.
DR   Pfam; PF07714; Pkinase_Tyr; 1.
DR   Pfam; PF00017; SH2; 1.
DR   Pfam; PF00018; SH3_1; 1.
DR   PRINTS; PR00401; SH2DOMAIN.
DR   PRINTS; PR00452; SH3DOMAIN.
DR   PRINTS; PR01887; SPECTRNALPHA.
DR   PRINTS; PR00109; TYRKINASE.
DR   SMART; SM00252; SH2; 1.
DR   SMART; SM00326; SH3; 1.
DR   SMART; SM00219; TyrKc; 1.
DR   SUPFAM; SSF50044; SSF50044; 1.
DR   SUPFAM; SSF56112; SSF56112; 1.
DR   PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00109; PROTEIN_KINASE_TYR; 1.
DR   PROSITE; PS50001; SH2; 1.
DR   PROSITE; PS50002; SH3; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; Kinase; Nucleotide-binding; SH3 domain; Transferase;
KW   Tyrosine-protein kinase.
SQ   SEQUENCE   524 AA;  59793 MW;  1BE3246F41C3C765 CRC64;
     MGNCFSRSRH PSMAAVPLNT RSGSSPKFST ELGIVEQLKE QNANEMGTPR RIETHSQQPD
     PANGKEVLIA LYAYESRAEG DLSFRKGDIM YLLDQSNSDW WYVRHSKGGT GYVPRNFVGK
     QQSVESEEWF AGRIPRNRAE RLVLASNLPK GTFLIREREA DTREYALTIR DSDDQRGGTV
     KHYKIRRLDG DAGFFITARR TFATLRDLVS YYSEVADGLC CQLSFPAPRI APTRPDLSHD
     TQQNWEIPRN QLQLKRKLGD GNFGDVWYGK WRGMVEVAIK TMKPGTMSPE AFLGEAQIMK
     QCDHPNLVKL YAVCTKEEPF YIITEYMVNG SLLHYLRNEG NSLTLQALVD MCAQIANGMM
     YLEERKLVHR DLAARNVLVG DKISGVPVVK VADFGLARKL MEEDIYEART GAKFPIKWTA
     PEAATCGNFT VKSDVWSYGV LLYEIITKGQ VPYPGMHNRE VIEQVELGYR MPMPRCCPEQ
     IYTEVMLKCW DKVPERRPTF DHLFHFFDDY FVSSQPNYVP PSQN
//