ID F1CME7_HUMAN Unreviewed; 359 AA. AC F1CME7; DT 03-MAY-2011, integrated into UniProtKB/TrEMBL. DT 03-MAY-2011, sequence version 1. DT 15-MAR-2017, entry version 25. DE SubName: Full=Hepatitis A virus cellular receptor 1b {ECO:0000313|EMBL:ADZ24773.1}; GN Name=HAVCR1 {ECO:0000313|EMBL:ADZ24773.1}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606 {ECO:0000313|EMBL:ADZ24773.1}; RN [1] {ECO:0000313|EMBL:ADZ24773.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=21412435; DOI=10.1371/journal.pone.0017787; RA Ivie S.E., Shang J., Rubin D.H., McClain M.S.; RT "Gene-trap mutagenesis identifies mammalian genes contributing to RT intoxication by Clostridium perfringens ?-toxin."; RL PLoS ONE 6:e17787-e17787(2011). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; HQ412640; ADZ24773.1; -; mRNA. DR UniGene; Hs.129711; -. DR STRING; 9606.ENSP00000344844; -. DR PaxDb; F1CME7; -. DR PeptideAtlas; F1CME7; -. DR eggNOG; ENOG410IZDR; Eukaryota. DR eggNOG; ENOG410YSF7; LUCA. DR ChiTaRS; HAVCR1; human. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR Gene3D; 2.60.40.10; -; 1. DR InterPro; IPR007110; Ig-like_dom. DR InterPro; IPR013783; Ig-like_fold. DR InterPro; IPR003006; Ig/MHC_CS. DR InterPro; IPR003599; Ig_sub. DR InterPro; IPR013106; Ig_V-set. DR Pfam; PF07686; V-set; 1. DR SMART; SM00409; IG; 1. DR SUPFAM; SSF48726; SSF48726; 1. DR PROSITE; PS50835; IG_LIKE; 1. DR PROSITE; PS00290; IG_MHC; 1. PE 2: Evidence at transcript level; KW Immunoglobulin domain {ECO:0000256|SAAS:SAAS00653601}; KW Membrane {ECO:0000256|SAM:Phobius}; KW Receptor {ECO:0000313|EMBL:ADZ24773.1}; KW Signal {ECO:0000256|SAM:SignalP}; KW Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}. FT SIGNAL 1 20 {ECO:0000256|SAM:SignalP}. FT CHAIN 21 359 {ECO:0000256|SAM:SignalP}. FT /FTId=PRO_5003266390. FT TRANSMEM 291 311 Helical. {ECO:0000256|SAM:Phobius}. FT DOMAIN 3 121 Ig-like (immunoglobulin-like). FT {ECO:0000259|PROSITE:PS50835}. SQ SEQUENCE 359 AA; 38674 MW; F5DC8ED8D40EF540 CRC64; MHPQVVILSL ILHLADSVAG SVKVGGEAGP SVTLPCHYSG AVTSMCWNRG SCSLFTCQNG IVWTNGTHVT YRKDTRYKLL GDLSRRDVSL TIENTAVSDS GVYCCRVEHR GWFNDMKITV SLEIVPPKVT TTPIVTTVPT VTTVRTSTTV PTTTTVPTTT VPTTMSIPTT TTVPTTMTVS TTTSVPTTTS IPTTTSVPVT TAVSTFVPPM PLPRQNHEPV ATSPSSPQPA ETHPTTLQGA IRREPTSSPL YSYTTDGNDT VTESSDGLWN NNQTQLFLEH SLLTANTTKG IYAGVCISVL VLLALLGVII AKKYFFKKEV QQLSVSFSSL QIKALQNAVE KEVQAEDNIY IENSLYATD //