ID E9Q559_MOUSE Unreviewed; 1026 AA. AC E9Q559; DT 05-APR-2011, integrated into UniProtKB/TrEMBL. DT 05-APR-2011, sequence version 1. DT 09-JUL-2014, entry version 26. DE SubName: Full=Sarcoplasmic/endoplasmic reticulum calcium ATPase 3; GN Name=Atp2a3; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., RA Lindblad-Toh K., Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of RT the mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] RP IDENTIFICATION. RC STRAIN=C57BL/6J; RG Ensembl; RL Submitted (MAY-2011) to UniProtKB. CC -!- SIMILARITY: Belongs to the cation transport ATPase (P-type) CC family. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AL663082; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AL670399; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; BX284667; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR RefSeq; NP_001156809.1; NM_001163337.1. DR UniGene; Mm.6306; -. DR ProteinModelPortal; E9Q559; -. DR SMR; E9Q559; 1-994. DR MaxQB; E9Q559; -. DR Ensembl; ENSMUST00000163326; ENSMUSP00000127036; ENSMUSG00000020788. DR GeneID; 53313; -. DR KEGG; mmu:53313; -. DR UCSC; uc011xym.1; mouse. DR CTD; 489; -. DR MGI; MGI:1194503; Atp2a3. DR GeneTree; ENSGT00560000076887; -. DR KO; K05853; -. DR ChiTaRS; ATP2A3; mouse. DR NextBio; 310097; -. DR ArrayExpress; E9Q559; -. DR Bgee; E9Q559; -. DR GO; GO:0005783; C:endoplasmic reticulum; IDA:MGI. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW. DR GO; GO:0005388; F:calcium-transporting ATPase activity; IEA:InterPro. DR GO; GO:0046872; F:metal ion binding; IEA:InterPro. DR Gene3D; 1.20.1110.10; -; 2. DR Gene3D; 2.70.150.10; -; 2. DR Gene3D; 3.40.1110.10; -; 1. DR InterPro; IPR005782; ATPase_P-typ_Ca-transp_IIA. DR InterPro; IPR006068; ATPase_P-typ_cation-transptr_C. DR InterPro; IPR004014; ATPase_P-typ_cation-transptr_N. DR InterPro; IPR023299; ATPase_P-typ_cyto_domN. DR InterPro; IPR018303; ATPase_P-typ_P_site. DR InterPro; IPR023298; ATPase_P-typ_TM_dom. DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A. DR InterPro; IPR001757; Cation_transp_P_typ_ATPase. DR InterPro; IPR023214; HAD-like_dom. DR Pfam; PF00689; Cation_ATPase_C; 1. DR Pfam; PF00690; Cation_ATPase_N; 1. DR Pfam; PF00122; E1-E2_ATPase; 1. DR Pfam; PF00702; Hydrolase; 1. DR PRINTS; PR00119; CATATPASE. DR SMART; SM00831; Cation_ATPase_N; 1. DR SUPFAM; SSF56784; SSF56784; 1. DR SUPFAM; SSF81660; SSF81660; 1. DR TIGRFAMs; TIGR01116; ATPase-IIA1_Ca; 1. DR TIGRFAMs; TIGR01494; ATPase_P-type; 2. DR PROSITE; PS00154; ATPASE_E1_E2; 1. PE 3: Inferred from homology; KW ATP-binding; Complete proteome; Hydrolase; Membrane; KW Nucleotide-binding; Reference proteome; Transmembrane; KW Transmembrane helix. SQ SEQUENCE 1026 AA; 112504 MW; E8EC0928C4E8F278 CRC64; MEEAHLLSAA DVLRRFSVTA EGGLSLEQVT DARERYGPNE LPTEEGKSLW ELVVEQFEDL LVRILLLAAL VSFVLAWFEE GEETTTAFVE PLVIMLILVA NAIVGVWQER NAESAIEALK EYEPEMGKVI RSDRKGVQRI RARDIVPGDI VEVAVGDKVP ADLRLIEIKS TTLRVDQSIL TGESVSVTKH TDAIPDPRAV NQDKKNMLFS GTNIASGKAL GVAVATGLQT ELGKIRSQMA AVEPERTPLQ RKLDEFGRQL SHAISVICVA VWVINIGHFA DPAHGGSWLR GAVYYFKIAV ALAVAAIPEG LPAVITTCLA LGTRRMARKN AIVRSLPSVE TLGCTSVICS DKTGTLTTNQ MSVCRMFVVA EAEAGTCRLH EFTISGTTYT PEGEVRQGEQ PVRCGQFDGL VELATICALC NDSALDYNEA KGVYEKVGEA TETALTCLVE KMNVFDTDLK GLSRVERAGA CNSVIKQLMR KEFTLEFSRD RKSMSVYCTP TRADPKVQGS KMFVKGAPES VIERCSSVRV GSRTAPLSTT SREHILAKIR DWGSGSDTLR CLALATRDTP PRKEDMHLDD CSRFVQYETD LTFVGCVGML DPPRPEVAAC ITRCSRAGIR VVMITGDNKG TAVAICRRLG IFGDTEDVLG KAYTGREFDD LSPEQQRQAC RTARCFARVE PAHKSRIVEN LQSFNEITAM TGDGVNDAPA LKKAEIGIAM GSGTAVAKSA AEMVLSDDNF ASIVAAVEEG RAIYNNMKQF IRYLISSNVG EVVCIFLTAI LGLPEALIPV QLLWVNLVTD GLPATALGFN PPDLDIMEKP PRNPREALIS GWLFFRYLAI GVYVGLATVA AATWWFLYDT EGPQVTFYQL RNFLKCSEDN PLFAGIDCKV FESRFPTTMA LSVLVTIEMC NALNSVSENQ SLLRMPPWLN PWLLGAVVMS MALHFLILLV PPLPLIFQVT PLSGRQWGVV LQMSLPVILL DEALKYLSRN HMDGVLGTFM QARSRQLPTT SRTPYHTGLA SWKKRT //