ID E9Q2L8_MOUSE Unreviewed; 91 AA. AC E9Q2L8; DT 05-APR-2011, integrated into UniProtKB/TrEMBL. DT 17-FEB-2016, sequence version 2. DT 14-DEC-2022, entry version 67. DE SubName: Full=Gamma-aminobutyric acid receptor subunit alpha-1 {ECO:0000313|Ensembl:ENSMUSP00000129056.3}; DE Flags: Fragment; GN Name=Gabra1 {ECO:0000313|Ensembl:ENSMUSP00000129056.3, GN ECO:0000313|MGI:MGI:95613}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000129056.3, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000129056.3, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000129056.3, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., RA Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of the RT mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000313|Ensembl:ENSMUSP00000129056.3} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000129056.3}; RG Ensembl; RL Submitted (AUG-2022) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR AlphaFoldDB; E9Q2L8; -. DR SMR; E9Q2L8; -. DR PeptideAtlas; E9Q2L8; -. DR ProteomicsDB; 314136; -. DR Antibodypedia; 4533; 506 antibodies from 43 providers. DR Ensembl; ENSMUST00000153147.3; ENSMUSP00000129056.3; ENSMUSG00000010803.14. DR AGR; MGI:95613; -. DR MGI; MGI:95613; Gabra1. DR VEuPathDB; HostDB:ENSMUSG00000010803; -. DR GeneTree; ENSGT00940000159136; -. DR HOGENOM; CLU_010920_5_5_1; -. DR OMA; ELHKPAM; -. DR ChiTaRS; Gabra1; mouse. DR Proteomes; UP000000589; Chromosome 11. DR Bgee; ENSMUSG00000010803; Expressed in cerebellum lobe and 170 other tissues. DR ExpressionAtlas; E9Q2L8; baseline and differential. DR GO; GO:0016020; C:membrane; IEA:InterPro. DR GO; GO:0005230; F:extracellular ligand-gated ion channel activity; IEA:InterPro. DR GO; GO:0004890; F:GABA-A receptor activity; IEA:InterPro. DR Gene3D; 2.70.170.10; -; 1. DR InterPro; IPR001390; GABAAa_rcpt. DR InterPro; IPR006202; Neur_chan_lig-bd. DR InterPro; IPR036734; Neur_chan_lig-bd_sf. DR InterPro; IPR006201; Neur_channel. DR PANTHER; PTHR18945; NEUROTRANSMITTER GATED ION CHANNEL; 1. DR Pfam; PF02931; Neur_chan_LBD; 1. DR PRINTS; PR01079; GABAARALPHA. DR SUPFAM; SSF63712; Nicotinic receptor ligand binding domain-like; 1. PE 4: Predicted; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}; KW Signal {ECO:0000256|SAM:SignalP}. FT SIGNAL 1..27 FT /evidence="ECO:0000256|SAM:SignalP" FT CHAIN 28..91 FT /evidence="ECO:0000256|SAM:SignalP" FT /id="PRO_5006724073" FT DOMAIN 42..91 FT /note="Neur_chan_LBD" FT /evidence="ECO:0000259|Pfam:PF02931" FT NON_TER 91 FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000129056.3" SQ SEQUENCE 91 AA; 10450 MW; F828A2C1C2E6F401 CRC64; MKKSRGLSDY LWAWTLILST LSGRSYGQPS QDELKDNTTV FTRILDRLLD GYDNRLRPGL GERVTEVKTD IFVTSFGPVS DHDMEYTIDV F //