ID E9Q2L8_MOUSE Unreviewed; 91 AA. AC E9Q2L8; DT 05-APR-2011, integrated into UniProtKB/TrEMBL. DT 17-FEB-2016, sequence version 2. DT 07-NOV-2018, entry version 49. DE SubName: Full=Gamma-aminobutyric acid receptor subunit alpha-1 {ECO:0000313|Ensembl:ENSMUSP00000129056}; DE Flags: Fragment; GN Name=Gabra1 {ECO:0000313|Ensembl:ENSMUSP00000129056, GN ECO:0000313|MGI:MGI:95613}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000129056, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000129056, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000129056, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., RA Lindblad-Toh K., Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of RT the mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000313|Ensembl:ENSMUSP00000129056} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000129056}; RG Ensembl; RL Submitted (MAY-2011) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AL645751; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AL645752; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR SMR; E9Q2L8; -. DR PeptideAtlas; E9Q2L8; -. DR Ensembl; ENSMUST00000153147; ENSMUSP00000129056; ENSMUSG00000010803. DR MGI; MGI:95613; Gabra1. DR eggNOG; KOG3642; Eukaryota. DR eggNOG; ENOG410XNQG; LUCA. DR GeneTree; ENSGT00760000119010; -. DR OMA; EYLWAWT; -. DR Proteomes; UP000000589; Chromosome 11. DR Bgee; ENSMUSG00000010803; Expressed in 190 organ(s), highest expression level in cerebellum. DR ExpressionAtlas; E9Q2L8; baseline and differential. DR GO; GO:0098982; C:GABA-ergic synapse; IEA:Ensembl. DR GO; GO:0016021; C:integral component of membrane; IEA:InterPro. DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl. DR GO; GO:0004890; F:GABA-A receptor activity; IEA:InterPro. DR GO; GO:1904315; F:transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential; IEA:Ensembl. DR Gene3D; 2.70.170.10; -; 1. DR InterPro; IPR001390; GABAAa_rcpt. DR InterPro; IPR006202; Neur_chan_lig-bd. DR InterPro; IPR036734; Neur_chan_lig-bd_sf. DR InterPro; IPR006201; Neur_channel. DR PANTHER; PTHR18945; PTHR18945; 1. DR Pfam; PF02931; Neur_chan_LBD; 1. DR PRINTS; PR01079; GABAARALPHA. DR SUPFAM; SSF63712; SSF63712; 1. PE 4: Predicted; KW Complete proteome {ECO:0000313|Proteomes:UP000000589}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}; KW Signal {ECO:0000256|SAM:SignalP}. FT SIGNAL 1 27 {ECO:0000256|SAM:SignalP}. FT CHAIN 28 91 {ECO:0000256|SAM:SignalP}. FT /FTId=PRO_5006724073. FT DOMAIN 42 91 Neur_chan_LBD. {ECO:0000259|Pfam: FT PF02931}. FT NON_TER 91 91 {ECO:0000313|Ensembl:ENSMUSP00000129056}. SQ SEQUENCE 91 AA; 10450 MW; F828A2C1C2E6F401 CRC64; MKKSRGLSDY LWAWTLILST LSGRSYGQPS QDELKDNTTV FTRILDRLLD GYDNRLRPGL GERVTEVKTD IFVTSFGPVS DHDMEYTIDV F //