ID E9Q2L8_MOUSE Unreviewed; 84 AA. AC E9Q2L8; DT 05-APR-2011, integrated into UniProtKB/TrEMBL. DT 05-APR-2011, sequence version 1. DT 09-DEC-2015, entry version 32. DE SubName: Full=Gamma-aminobutyric acid receptor subunit alpha-1 {ECO:0000313|Ensembl:ENSMUSP00000129056}; DE Flags: Fragment; GN Name=Gabra1 {ECO:0000313|Ensembl:ENSMUSP00000129056, GN ECO:0000313|MGI:MGI:95613}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000129056, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000129056, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000129056, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., RA Lindblad-Toh K., Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of RT the mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000313|Ensembl:ENSMUSP00000129056} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000129056}; RG Ensembl; RL Submitted (MAY-2011) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. {ECO:0000313|Ensembl:ENSMUSP00000129056}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AL645751; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AL645752; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR STRING; 10090.ENSMUSP00000020707; -. DR BindingDB; E9Q2L8; -. DR PaxDb; E9Q2L8; -. DR Ensembl; ENSMUST00000153147; ENSMUSP00000129056; ENSMUSG00000010803. DR MGI; MGI:95613; Gabra1. DR eggNOG; ENOG410XNQG; LUCA. DR eggNOG; KOG3642; Eukaryota. DR GeneTree; ENSGT00760000119010; -. DR NextBio; 35554865; -. DR Proteomes; UP000000589; Chromosome 11. DR Bgee; E9Q2L8; -. DR ExpressionAtlas; E9Q2L8; baseline and differential. DR GO; GO:1902711; C:GABA-A receptor complex; IBA:GO_Central. DR GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central. DR GO; GO:0043005; C:neuron projection; IBA:GO_Central. DR GO; GO:0005886; C:plasma membrane; IDA:MGI. DR GO; GO:0045202; C:synapse; IBA:GO_Central. DR GO; GO:0005254; F:chloride channel activity; IBA:GO_Central. DR GO; GO:0004890; F:GABA-A receptor activity; IEA:InterPro. DR GO; GO:0005237; F:inhibitory extracellular ligand-gated ion channel activity; IBA:GO_Central. DR GO; GO:1902476; P:chloride transmembrane transport; IBA:GO_Central. DR GO; GO:0007214; P:gamma-aminobutyric acid signaling pathway; IBA:GO_Central. DR GO; GO:0050877; P:neurological system process; IBA:GO_Central. DR GO; GO:0042391; P:regulation of membrane potential; IBA:GO_Central. DR GO; GO:0042493; P:response to drug; IBA:GO_Central. DR GO; GO:0007268; P:synaptic transmission; IBA:GO_Central. DR Gene3D; 2.70.170.10; -; 1. DR InterPro; IPR001390; GABAAa_rcpt. DR InterPro; IPR006202; Neur_chan_lig-bd. DR InterPro; IPR006201; Neur_channel. DR PANTHER; PTHR18945; PTHR18945; 1. DR PRINTS; PR01079; GABAARALPHA. DR SUPFAM; SSF63712; SSF63712; 1. PE 4: Predicted; KW Complete proteome {ECO:0000313|Proteomes:UP000000589}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}; KW Signal {ECO:0000256|SAM:SignalP}. FT SIGNAL 1 27 {ECO:0000256|SAM:SignalP}. FT CHAIN 28 84 {ECO:0000256|SAM:SignalP}. FT /FTId=PRO_5003243059. FT NON_TER 84 84 {ECO:0000313|Ensembl:ENSMUSP00000129056}. SQ SEQUENCE 84 AA; 9582 MW; 01FE83C96C906585 CRC64; MKKSRGLSDY LWAWTLILST LSGRSYGQPS QDELKDNTTV FTRILDRLLD GYDNRLRPGL GERVTEVKTD IFVTSFGPVS DHDM //