ID E9PWM8_MOUSE Unreviewed; 178 AA. AC E9PWM8; DT 05-APR-2011, integrated into UniProtKB/TrEMBL. DT 05-APR-2011, sequence version 1. DT 29-MAY-2024, entry version 82. DE SubName: Full=Activating transcription factor 1 {ECO:0000313|Ensembl:ENSMUSP00000132907.2}; DE Flags: Fragment; GN Name=Atf1 {ECO:0000313|Ensembl:ENSMUSP00000132907.2, GN ECO:0000313|MGI:MGI:1298366}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000132907.2, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000132907.2, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000132907.2, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., RA Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of the RT mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000313|Ensembl:ENSMUSP00000132907.2} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000132907.2}; RG Ensembl; RL Submitted (FEB-2024) to UniProtKB. CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR AlphaFoldDB; E9PWM8; -. DR SMR; E9PWM8; -. DR MaxQB; E9PWM8; -. DR PeptideAtlas; E9PWM8; -. DR ProteomicsDB; 357636; -. DR Antibodypedia; 4260; 795 antibodies from 44 providers. DR Ensembl; ENSMUST00000172154.8; ENSMUSP00000132907.2; ENSMUSG00000023027.14. DR AGR; MGI:1298366; -. DR MGI; MGI:1298366; Atf1. DR VEuPathDB; HostDB:ENSMUSG00000023027; -. DR GeneTree; ENSGT00940000158200; -. DR OMA; THISHIA; -. DR ChiTaRS; Atf1; mouse. DR Proteomes; UP000000589; Chromosome 15. DR Bgee; ENSMUSG00000023027; Expressed in cumulus cell and 268 other cell types or tissues. DR ExpressionAtlas; E9PWM8; baseline and differential. DR GO; GO:1990589; C:ATF4-CREB1 transcription factor complex; IEA:TreeGrafter. DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:TreeGrafter. DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter. DR InterPro; IPR003102; CREB1-like_pKID. DR InterPro; IPR001630; Leuzip_CREB. DR PANTHER; PTHR45879; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN B; 1. DR PANTHER; PTHR45879:SF2; CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-1; 1. DR Pfam; PF02173; pKID; 1. DR PRINTS; PR00041; LEUZIPPRCREB. DR PROSITE; PS50953; KID; 1. PE 1: Evidence at protein level; KW DNA-binding {ECO:0000256|ARBA:ARBA00023125}; KW Nucleus {ECO:0000256|ARBA:ARBA00023242}; KW Proteomics identification {ECO:0007829|EPD:E9PWM8, KW ECO:0007829|PeptideAtlas:E9PWM8}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}; KW Transcription {ECO:0000256|ARBA:ARBA00023163}; KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}. FT DOMAIN 31..90 FT /note="KID" FT /evidence="ECO:0000259|PROSITE:PS50953" FT REGION 1..90 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 8..52 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 63..82 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT NON_TER 178 FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000132907.2" SQ SEQUENCE 178 AA; 18727 MW; A6BA4500B09F13F2 CRC64; MEDSHKSNTT ETASQPGSTV AGPHVSQIVH QVSSLSESEE SQDSSDSIGS SQKAHGILAR RPSYRKILKD LSSEDTRGRK GEGENPSISA ITSMSVPAPI YQTSSGQYIA IAPNGALQLA SPSTDGVQAL QTLTMTNSSS TQQGTILQYA QTSDGQQILV PSNQVVVQTA SGDMQTYQ //