ID E9PWE3_MOUSE Unreviewed; 645 AA. AC E9PWE3; DT 05-APR-2011, integrated into UniProtKB/TrEMBL. DT 05-APR-2011, sequence version 1. DT 15-FEB-2017, entry version 48. DE SubName: Full=Transcription factor E2-alpha {ECO:0000313|Ensembl:ENSMUSP00000100978}; GN Name=Tcf3 {ECO:0000313|Ensembl:ENSMUSP00000100978, GN ECO:0000313|MGI:MGI:98510}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000100978, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000100978, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000100978, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., RA Lindblad-Toh K., Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of RT the mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000213|PubMed:21183079} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001; RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R., RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.; RT "A tissue-specific atlas of mouse protein phosphorylation and RT expression."; RL Cell 143:1174-1189(2010). RN [3] {ECO:0000313|Ensembl:ENSMUSP00000100978} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000100978}; RG Ensembl; RL Submitted (MAY-2011) to UniProtKB. RN [4] {ECO:0000213|PubMed:24129315} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=24129315; RA Guo A., Gu H., Zhou J., Mulhern D., Wang Y., Lee K.A., Yang V., RA Aguiar M., Kornhauser J., Jia X., Ren J., Beausoleil S.A., Silva J.C., RA Vemulapalli V., Bedford M.T., Comb M.J.; RT "Immunoaffinity enrichment and mass spectrometry analysis of protein RT methylation."; RL Mol. Cell. Proteomics 13:372-387(2014). CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. {ECO:0000313|Ensembl:ENSMUSP00000100978}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC152062; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR ProteinModelPortal; E9PWE3; -. DR SMR; E9PWE3; -. DR STRING; 10090.ENSMUSP00000100979; -. DR MaxQB; E9PWE3; -. DR PaxDb; E9PWE3; -. DR PeptideAtlas; E9PWE3; -. DR Ensembl; ENSMUST00000105341; ENSMUSP00000100978; ENSMUSG00000020167. DR MGI; MGI:98510; Tcf3. DR eggNOG; KOG3910; Eukaryota. DR eggNOG; ENOG410XYUA; LUCA. DR GeneTree; ENSGT00510000046438; -. DR ChiTaRS; Tcf3; mouse. DR Proteomes; UP000000589; Chromosome 10. DR Bgee; ENSMUSG00000020167; -. DR ExpressionAtlas; E9PWE3; baseline and differential. DR Gene3D; 4.10.280.10; -; 1. DR InterPro; IPR011598; bHLH_dom. DR Pfam; PF00010; HLH; 1. DR SMART; SM00353; HLH; 1. DR SUPFAM; SSF47459; SSF47459; 1. DR PROSITE; PS50888; BHLH; 1. PE 1: Evidence at protein level; KW Complete proteome {ECO:0000313|Proteomes:UP000000589}; KW Proteomics identification {ECO:0000213|MaxQB:E9PWE3, KW ECO:0000213|PeptideAtlas:E9PWE3}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}. FT DOMAIN 540 593 BHLH (basic helix-loop-helix). FT {ECO:0000259|PROSITE:PS50888}. SQ SEQUENCE 645 AA; 67103 MW; EC88146F49974ED1 CRC64; MMNQSQRMAP VGSDKELSDL LDFSMMFPLP VANGKSRPAS LGGTQFAGSG LEDRPSSGSW GSSDQNSSSF DPSRTYSEGA HFSDSHSSLP PSTFLGAGLG GKGSERNAYA TFGRDTSVGT LSQAGFLPGE LSLSSPGPLS PSGIKSSSQY YPSFPSNPRR RAADGGLDTQ PKKVRKVPPG LPSSVYPPSS GDSYSRDAAA YPSAKTPSSA YPSPFYVADG SLHPSAELWS TPSQVGFGPM LGDGSSPLPL APGSSSVGSG TFGGLQQQDR MGYQLHGSEV NGSLPAVSSF SAAPGTYSGT SGHTPPVSGA AAESLLGTTA SSSGDALGKA LASIYSPDHS SNNFSPSPST PVGSPQGLPG TSQWPRAGAP SALSPNYDAG LHGLSKMEDR LDEAIHVLRS HAVGTASDLH GLLPGHGALT TSFTGPMSLG GRHAGLVGGS HPEEGLTSGA SLLHNHASLP SQPSSLPDLS QRPPDSYSGL GRAGTTAGAS EIKREEKEDE EIASVADAEE DKKDLKVPRT RTSSTDEVLS LEEKDLRDRE RRMANNARER VRVRDINEAF RELGRMCQLH LKSDKAQTKL LILQQAVQVI LGLEQQVRER NLNPKAACLK RREEEKVSGV VGDPQLALSA AHPGLGEAHN PAGHL //