ID E9PPR2_HUMAN Unreviewed; 119 AA. AC E9PPR2; DT 05-APR-2011, integrated into UniProtKB/TrEMBL. DT 05-APR-2011, sequence version 1. DT 08-MAY-2019, entry version 50. DE RecName: Full=Autophagy-related protein 13 {ECO:0000256|RuleBase:RU361214}; DE Flags: Fragment; GN Name=ATG13 {ECO:0000313|Ensembl:ENSP00000436931}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000436931, ECO:0000313|Proteomes:UP000005640}; RN [1] {ECO:0000313|Ensembl:ENSP00000436931, ECO:0000313|Proteomes:UP000005640} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=16554811; DOI=10.1038/nature04632; RA Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K., RA Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T., RA Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G., RA Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C., RA Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A., RA Hattori M., Rogers J., Lander E.S., Sakaki Y.; RT "Human chromosome 11 DNA sequence and analysis including novel gene RT identification."; RL Nature 440:497-500(2006). RN [2] {ECO:0000213|PubMed:19413330} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=19413330; DOI=10.1021/ac9004309; RA Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., RA Mohammed S.; RT "Lys-N and trypsin cover complementary parts of the phosphoproteome in RT a refined SCX-based approach."; RL Anal. Chem. 81:4493-4501(2009). RN [3] {ECO:0000313|Ensembl:ENSP00000436931} RP IDENTIFICATION. RG Ensembl; RL Submitted (JUL-2011) to UniProtKB. RN [4] {ECO:0000213|PubMed:22814378} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=22814378; DOI=10.1073/pnas.1210303109; RA Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A., RA Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., RA Timmerman E., Prieto J., Arnesen T., Sherman F., Gevaert K., RA Aldabe R.; RT "N-terminal acetylome analyses and functional insights of the N- RT terminal acetyltransferase NatB."; RL Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012). RN [5] {ECO:0000213|PubMed:23186163} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=23186163; RA Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J., RA Mohammed S.; RT "Toward a comprehensive characterization of a human cancer cell RT phosphoproteome."; RL J. Proteome Res. 12:260-271(2013). CC -!- SIMILARITY: Belongs to the ATG13 family. Metazoan subfamily. CC {ECO:0000256|RuleBase:RU361214}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC115088; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC127035; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR MaxQB; E9PPR2; -. DR PeptideAtlas; E9PPR2; -. DR PRIDE; E9PPR2; -. DR Ensembl; ENST00000533325; ENSP00000436931; ENSG00000175224. DR UCSC; uc058axg.1; human. DR HGNC; HGNC:29091; ATG13. DR OpenTargets; ENSG00000175224; -. DR eggNOG; KOG3874; Eukaryota. DR eggNOG; ENOG410YGTM; LUCA. DR GeneTree; ENSGT00390000007055; -. DR ChiTaRS; ATG13; human. DR Proteomes; UP000005640; Chromosome 11. DR Bgee; ENSG00000175224; Expressed in 228 organ(s), highest expression level in right testis. DR ExpressionAtlas; E9PPR2; baseline and differential. DR GO; GO:1990316; C:Atg1/ULK1 kinase complex; IEA:InterPro. DR GO; GO:0000045; P:autophagosome assembly; IEA:InterPro. DR Gene3D; 3.30.900.10; -; 1. DR InterPro; IPR040182; ATG13. DR InterPro; IPR018731; Atg13_N. DR InterPro; IPR036570; HORMA_dom_sf. DR PANTHER; PTHR13430; PTHR13430; 1. DR Pfam; PF10033; ATG13; 1. PE 1: Evidence at protein level; KW Autophagy {ECO:0000256|RuleBase:RU361214}; KW Complete proteome {ECO:0000313|Proteomes:UP000005640}; KW Proteomics identification {ECO:0000213|EPD:E9PPR2, KW ECO:0000213|MaxQB:E9PPR2, ECO:0000213|PeptideAtlas:E9PPR2}; KW Reference proteome {ECO:0000313|Proteomes:UP000005640}. FT DOMAIN 19 93 ATG13. {ECO:0000259|Pfam:PF10033}. FT NON_TER 119 119 {ECO:0000313|Ensembl:ENSP00000436931}. SQ SEQUENCE 119 AA; 13422 MW; 5127A1DF5984A45F CRC64; METDLNSQDR KDLDKFIKFF ALKTVQVIVQ ARLGEKICTR SSSSPTGSDW FNLAIKDIPE VTHEAKKALA GQLPAVGRSM CVEISLKTSE GDSMELEIWC LEMNEKCDKE IKVSYTVYN //