ID E9PNW5_HUMAN Unreviewed; 1508 AA. AC E9PNW5; DT 05-APR-2011, integrated into UniProtKB/TrEMBL. DT 05-OCT-2016, sequence version 2. DT 08-MAY-2019, entry version 41. DE SubName: Full=Uncharacterized protein C4orf50 {ECO:0000313|Ensembl:ENSP00000437121}; GN Name=C4orf50 {ECO:0000313|Ensembl:ENSP00000437121}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000437121, ECO:0000313|Proteomes:UP000005640}; RN [1] {ECO:0000313|Ensembl:ENSP00000437121, ECO:0000313|Proteomes:UP000005640} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=15815621; DOI=10.1038/nature03466; RA Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., RA Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., RA Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., RA Kremitzki C., Oddy L., Du H., Sun H., Bradshaw-Cordum H., Ali J., RA Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., RA Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., RA Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., RA Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., RA Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., RA Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., RA McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., RA Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., RA Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., RA Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., RA Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., RA Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., RA Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., RA Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., RA Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., RA Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., RA McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., RA Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., RA Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., RA Waterston R.H., Wilson R.K.; RT "Generation and annotation of the DNA sequences of human chromosomes 2 RT and 4."; RL Nature 434:724-731(2005). RN [2] {ECO:0000313|Ensembl:ENSP00000437121} RP IDENTIFICATION. RG Ensembl; RL Submitted (JUL-2011) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC092442; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC105915; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC109593; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC113615; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR PeptideAtlas; E9PNW5; -. DR PRIDE; E9PNW5; -. DR Ensembl; ENST00000531445; ENSP00000437121; ENSG00000181215. DR UCSC; uc062uxw.1; human. DR HGNC; HGNC:33766; C4orf50. DR OpenTargets; ENSG00000181215; -. DR eggNOG; ENOG410J1QI; Eukaryota. DR eggNOG; ENOG410YTRB; LUCA. DR GeneTree; ENSGT00390000003220; -. DR OMA; PLDELGC; -. DR TreeFam; TF353371; -. DR Proteomes; UP000005640; Chromosome 4. DR Bgee; ENSG00000181215; Expressed in 23 organ(s), highest expression level in caudate nucleus. DR ExpressionAtlas; E9PNW5; baseline and differential. DR InterPro; IPR032771; DUF4527. DR Pfam; PF15030; DUF4527; 1. PE 4: Predicted; KW Coiled coil {ECO:0000256|SAM:Coils}; KW Complete proteome {ECO:0000313|Proteomes:UP000005640}; KW Reference proteome {ECO:0000313|Proteomes:UP000005640}. FT COILED 65 85 {ECO:0000256|SAM:Coils}. FT COILED 149 169 {ECO:0000256|SAM:Coils}. FT COILED 188 215 {ECO:0000256|SAM:Coils}. FT COILED 233 267 {ECO:0000256|SAM:Coils}. FT COILED 972 1006 {ECO:0000256|SAM:Coils}. FT COILED 1014 1034 {ECO:0000256|SAM:Coils}. FT COILED 1082 1102 {ECO:0000256|SAM:Coils}. FT COILED 1271 1302 {ECO:0000256|SAM:Coils}. SQ SEQUENCE 1508 AA; 167146 MW; FDECFB5C8C7FA9FC CRC64; MEPTAKGRTE ESFSYVIRAP SSEGFDIMNV DVKIDTSWIF QDMEDSAEER ECLQEEAAGR PDMDMGALRR QLESSEQKLS AAEDKYVTSE SGLRSRIQEL ELSERKLLRK VDQLSTHVAQ ERSAWLQAQE KLAALQGELA SQIREESVAR RQQWRLRRLQ ERLRRKDEAL GQQAAALERC RRTQRRQLGL VREQERVLRE QVQRLERNVR RLCRAAGLLL AQWDTAAPGS QGATEAAAEL RALQARAERS EREREEAARS LQEHRATERQ LRGQLEELRC CIYGLKLSEI GLQGQVEDLA QQNQCLREEL GAQAPIGHCS LDALGCVQGD SLPLPREEAL DPCRSQDWRN SLRSNDAPRQ RAPAGQSPEG PCTWSRIRPG RASSVLAPGP ETTSELPRDL AGSNREQLTL AEPSLDEQIL LLVCGCPPEE CLDESLLRMD LAWISENLAA DPAAEAFLLV QTSALPLWGP AGDSASWRPL LLQEVPSDGQ KIQEELATRS PPPPKATGHP GWDCHQTRGR GASLFHEAPY ISNHPFLKKH PKDLKDTWNN GGGSLAGRTE EGKARGTLGR KGKNLGDKYQ LSQESHQNLS LENGAGAAED VQDQNGASET KAATCRPGSW QEFLMPLLQG EASVSKEGPE SLSRRERVEG YVWGLRGGLS SENEEVAPPA TFSRAHETKE PWPTDSQLLA GKVRATGRTA RGKEENQVWL GNALLLQGGS LEDKGLEEED EMPHQEASGL GCRGAPEEPD SQEHESKEML FFAGETGLPL FPRFALSVEG AEPTDHGHPQ AVSKGHNRCA LTIDELAQDV EACFQQLSTL QPGSRGWQCS ASACRGENWS FAQKWHSGWE RAHSQQVWGN WGICSNEEAK SKESGEGDKP GKTTALGTSE VPGNPGTLPH WDEASPNPPQ GPAEPWGALE RVRSRFHQLI SGLKKQRSQI LHDNTKLHGD QERFHERVCA LEREREREVT KISRLERDNH RLVGDISQLK KELDQYLQAI SDLEDCNGKS YCKILELEEE NETLKGNLGQ LQKATSESVR KSKDTMEQVT LENWKLQTLI SELGVSYKEL IKDIVLGIED MIRALSGENE HLLRRVHVLE REVTLQRSTD QGRLVRGREH LQGKAKMHAL DKEVQVTPLT GQLLSRACGP PLEEEMSLAA GQTGPSTGTG NSRRGADSPP PSLVWRNTGV ANALQGNVSG AEVKEAHLEK EEKRPRCSVA QGQALSSLSN GPMLRDSEAE VTEEDPRLRA QQLHHRVLTL QCQLRDQGAA HQASLDEATR LQEELQAKLE ELQKKQHEAK LAVTPLKAKI ASLVRKCRER NRLITHLLQE LHRHGLGNLL LSELAQNMLN DVALAEYTAT FLAPGVPETS HHLDVKSEMT AALRAQTYLL NPEMDSVLQS SLSSESWPIP EPEWPAQTAQ LDSLKLPLSL VSTLDPGTCL AAVTVEPGLP AQRLQEKGGM PCPALQVDNV PAPSELLSPA RILAFHQELR QSICSNSQVH KSPLELEM //