ID E9PFG6_HUMAN Unreviewed; 97 AA. AC E9PFG6; A1IMF2; DT 05-APR-2011, integrated into UniProtKB/TrEMBL. DT 28-JUN-2011, sequence version 2. DT 16-NOV-2011, entry version 8. DE SubName: Full=Heparanase; DE SubName: Full=Uncharacterized protein; GN Name=HPSE; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=15815621; DOI=10.1038/nature03466; RA Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., RA Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., RA Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., RA Kremitzki C., Oddy L., Du H., Sun H., Bradshaw-Cordum H., Ali J., RA Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., RA Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., RA Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., RA Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., RA Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., RA Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., RA McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., RA Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., RA Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., RA Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., RA Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., RA Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., RA Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., RA Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., RA Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., RA Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., RA McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., RA Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., RA Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., RA Waterston R.H., Wilson R.K.; RT "Generation and annotation of the DNA sequences of human chromosomes 2 RT and 4."; RL Nature 434:724-731(2005). RN [2] RP IDENTIFICATION. RG Ensembl; RL Submitted (JUL-2011) to UniProtKB. RN [3] RP NUCLEOTIDE SEQUENCE. RC TISSUE=Fetal kidney; RA Quiros L.M.; RT "Identification of a new heparanase spliced variant in human fetal RT kidney."; RL Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC114781; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AJ627581; CAF28887.1; -; mRNA. DR IPI; IPI01009943; -. DR ProteinModelPortal; E9PFG6; -. DR STRING; A1IMF2; -. DR Ensembl; ENST00000454730; ENSP00000409711; ENSG00000173083. DR KEGG; hsa:10855; -. DR HGNC; HGNC:5164; HPSE. DR Bgee; A1IMF2; -. DR GO; GO:0016020; C:membrane; IEA:InterPro. DR GO; GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:InterPro. DR InterPro; IPR005199; Glyco_hydro_79. DR InterPro; IPR017853; Glycoside_hydrolase_SF. DR PANTHER; PTHR14363; Glyco_hydro_79_N; 1. DR Pfam; PF03662; Glyco_hydro_79n; 1. DR SUPFAM; SSF51445; Glyco_hydro_cat; 1. PE 2: Evidence at transcript level; KW Complete proteome; Reference proteome. FT NON_TER 97 97 SQ SEQUENCE 97 AA; 10338 MW; F7CFAFE472BCF2BB CRC64; MLLLLGPLGP LSPGALPRPA QAQDVVDLDF FTQEPLHLVS PSFLSVTRPG KKVWLGETSS AYGGGAPLLS DTFAAGFMWL DKLGLSARMG IEVVMRQ //