ID E9PC45_HUMAN Unreviewed; 93 AA. AC E9PC45; DT 05-APR-2011, integrated into UniProtKB/TrEMBL. DT 05-APR-2011, sequence version 1. DT 29-OCT-2014, entry version 30. DE SubName: Full=Platelet glycoprotein 4 {ECO:0000313|Ensembl:ENSP00000409762}; DE Flags: Fragment; GN Name=CD36 {ECO:0000313|Ensembl:ENSP00000409762}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000409762, ECO:0000313|Proteomes:UP000005640}; RN [1] {ECO:0000313|Ensembl:ENSP00000409762, ECO:0000313|Proteomes:UP000005640} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=12853948; DOI=10.1038/nature01782; RA Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., RA Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., RA Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., RA Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H., RA Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., RA Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., RA Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., RA Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., RA Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., RA Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., RA Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., RA Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., RA Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., RA Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., RA Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., RA Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., RA Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., RA Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., RA Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., RA Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., RA Waterston R.H., Wilson R.K.; RT "The DNA sequence of human chromosome 7."; RL Nature 424:157-164(2003). RN [2] {ECO:0000313|Ensembl:ENSP00000409762} RP IDENTIFICATION. RG Ensembl; RL Submitted (JUL-2011) to UniProtKB. RN [3] {ECO:0000313|Ensembl:ENSP00000398760} RP IDENTIFICATION. RG Ensembl; RL Submitted (FEB-2012) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. {ECO:0000313|Ensembl:ENSP00000409762}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC004862; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC073182; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC073850; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC092108; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC124834; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; KF458491; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; KF458494; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR ProteinModelPortal; E9PC45; -. DR Ensembl; ENST00000428497; ENSP00000409762; ENSG00000135218. DR Ensembl; ENST00000436384; ENSP00000398760; ENSG00000135218. DR HGNC; HGNC:1663; CD36. DR GeneTree; ENSGT00530000062927; -. DR NextBio; 35501488; -. DR ExpressionAtlas; E9PC45; baseline and differential. DR GO; GO:0009897; C:external side of plasma membrane; IEA:Ensembl. DR GO; GO:0005794; C:Golgi apparatus; IEA:Ensembl. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0045121; C:membrane raft; IEA:Ensembl. DR GO; GO:0008035; F:high-density lipoprotein particle binding; IEA:Ensembl. DR GO; GO:0070892; F:lipoteichoic acid receptor activity; IEA:Ensembl. DR GO; GO:0030169; F:low-density lipoprotein particle binding; IEA:Ensembl. DR GO; GO:0005041; F:low-density lipoprotein receptor activity; IEA:Ensembl. DR GO; GO:0043277; P:apoptotic cell clearance; IEA:Ensembl. DR GO; GO:0007155; P:cell adhesion; IEA:InterPro. DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:Ensembl. DR GO; GO:0071221; P:cellular response to bacterial lipopeptide; IEA:Ensembl. DR GO; GO:0071447; P:cellular response to hydroperoxide; IEA:Ensembl. DR GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl. DR GO; GO:0071223; P:cellular response to lipoteichoic acid; IEA:Ensembl. DR GO; GO:0030301; P:cholesterol transport; IEA:Ensembl. DR GO; GO:0050830; P:defense response to Gram-positive bacterium; IEA:Ensembl. DR GO; GO:0019915; P:lipid storage; IEA:Ensembl. DR GO; GO:0042953; P:lipoprotein transport; IEA:Ensembl. DR GO; GO:0034383; P:low-density lipoprotein particle clearance; IEA:Ensembl. DR GO; GO:0055096; P:low-density lipoprotein particle mediated signaling; IEA:Ensembl. DR GO; GO:0044130; P:negative regulation of growth of symbiont in host; IEA:Ensembl. DR GO; GO:0042992; P:negative regulation of transcription factor import into nucleus; IEA:Ensembl. DR GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl. DR GO; GO:0006910; P:phagocytosis, recognition; IEA:Ensembl. DR GO; GO:0030194; P:positive regulation of blood coagulation; IEA:Ensembl. DR GO; GO:2000334; P:positive regulation of blood microparticle formation; IEA:Ensembl. DR GO; GO:0010886; P:positive regulation of cholesterol storage; IEA:Ensembl. DR GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEA:Ensembl. DR GO; GO:0032735; P:positive regulation of interleukin-12 production; IEA:Ensembl. DR GO; GO:0032755; P:positive regulation of interleukin-6 production; IEA:Ensembl. DR GO; GO:0060907; P:positive regulation of macrophage cytokine production; IEA:Ensembl. DR GO; GO:0010744; P:positive regulation of macrophage derived foam cell differentiation; IEA:Ensembl. DR GO; GO:0043410; P:positive regulation of MAPK cascade; IEA:Ensembl. DR GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IEA:Ensembl. DR GO; GO:0060100; P:positive regulation of phagocytosis, engulfment; IEA:Ensembl. DR GO; GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IEA:Ensembl. DR GO; GO:0032760; P:positive regulation of tumor necrosis factor production; IEA:Ensembl. DR GO; GO:2000121; P:regulation of removal of superoxide radicals; IEA:Ensembl. DR GO; GO:0035634; P:response to stilbenoid; IEA:Ensembl. DR InterPro; IPR002159; CD36. DR InterPro; IPR005428; CD36_antigen. DR PANTHER; PTHR11923; PTHR11923; 1. DR Pfam; PF01130; CD36; 1. DR PRINTS; PR01610; CD36ANTIGEN. DR PRINTS; PR01609; CD36FAMILY. PE 4: Predicted; KW Complete proteome {ECO:0000313|Proteomes:UP000005640}; KW Membrane {ECO:0000256|SAAS:SAAS00106188}; KW Reference proteome {ECO:0000313|Proteomes:UP000005640}; KW Transmembrane {ECO:0000256|SAAS:SAAS00106195}; KW Transmembrane helix {ECO:0000256|SAAS:SAAS00106193}. FT NON_TER 93 93 {ECO:0000313|Ensembl:ENSP00000409762}. SQ SEQUENCE 93 AA; 10338 MW; F598F88009B62E81 CRC64; MGCDRNCGLI AGAVIGAVLA VFGGILMPVG DLLIQKTIKK QVVLEEGTIA FKNWVKTGTE VYRQFWIFDV QNPQEVMMNS SNIQVKQRGP YTY //