ID E9L1F5_9ZZZZ Unreviewed; 447 AA. AC E9L1F5; DT 05-APR-2011, integrated into UniProtKB/TrEMBL. DT 05-APR-2011, sequence version 1. DT 19-JAN-2022, entry version 30. DE RecName: Full=UDP-MurNAc-pentapeptide synthetase {ECO:0000256|ARBA:ARBA00019300}; GN ORFNames=CA37-11 {ECO:0000313|EMBL:ADU56034.1}; OS uncultured organism CA37. OC unclassified sequences; environmental samples. OX NCBI_TaxID=941420 {ECO:0000313|EMBL:ADU56034.1}; RN [1] {ECO:0000313|EMBL:ADU56034.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=20945895; DOI=10.1021/ja105825a; RA Banik J.J., Craig J.W., Calle P.Y., Brady S.F.; RT "Tailoring enzyme-rich environmental DNA clones: a source of enzymes for RT generating libraries of unnatural natural products."; RL J. Am. Chem. Soc. 132:15661-15670(2010). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; HM486074; ADU56034.1; -; Genomic_DNA. DR GO; GO:0005524; F:ATP binding; IEA:InterPro. DR GO; GO:0047480; F:UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity; IEA:InterPro. DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro. DR GO; GO:0071555; P:cell wall organization; IEA:InterPro. DR Gene3D; 3.40.1190.10; -; 1. DR Gene3D; 3.90.190.20; -; 1. DR HAMAP; MF_02019; MurF; 1. DR InterPro; IPR036565; Mur-like_cat_sf. DR InterPro; IPR004101; Mur_ligase_C. DR InterPro; IPR036615; Mur_ligase_C_dom_sf. DR InterPro; IPR013221; Mur_ligase_cen. DR InterPro; IPR000713; Mur_ligase_N. DR InterPro; IPR035911; MurE/MurF_N. DR InterPro; IPR005863; UDP-N-AcMur_synth. DR Pfam; PF01225; Mur_ligase; 1. DR Pfam; PF02875; Mur_ligase_C; 1. DR Pfam; PF08245; Mur_ligase_M; 1. DR SUPFAM; SSF53244; SSF53244; 1. DR SUPFAM; SSF53623; SSF53623; 1. DR SUPFAM; SSF63418; SSF63418; 1. DR TIGRFAMs; TIGR01143; murF; 1. PE 3: Inferred from homology; FT DOMAIN 31..81 FT /note="Mur_ligase" FT /evidence="ECO:0000259|Pfam:PF01225" FT DOMAIN 108..293 FT /note="Mur_ligase_M" FT /evidence="ECO:0000259|Pfam:PF08245" FT DOMAIN 317..393 FT /note="Mur_ligase_C" FT /evidence="ECO:0000259|Pfam:PF02875" SQ SEQUENCE 447 AA; 45305 MW; 14C4C09420C74971 CRC64; MIPLSLDEIA AVVSGTVEGD GAVTVTAPAV LDGRQAEPGG LFVAFAGEHV DGHDYAGQAG RAGAVAVLGS RPTTLPTVVV EDARAALQAL AAHVVARLRD RLTVVGLTGS QGKTSTKDLL AAVLSHTGST VATIGSLNNE LGVPLTMLRT TPDTRFLVLE MGARGIGHIA ELTALVALDV AVVLNVGQAH IGEFGSREAI ATAKAELLQG LVPGGTAILN ADDPRVLVMR ALTDGPALTF GRAEHAHVRV LDLALDRLGR PAFTLRTADA SAPVALPLVG AHQALNASAA AAAGLAAGIP LDVTAATLAT ASLSKWRMEL RGLSGGVSLL NDSYNANPDS TRAALDALAA IEAGRRIAVL GEMRELGDDS EAEHRAIGEY AARAADLVVA VGEAAAPIAE GAGDRAVALA DNDAAVDWLR RALTAGDVVL VKASRLARLD EVAAALA //