ID E9KMS1_9INFA Unreviewed; 759 AA. AC E9KMS1; DT 05-APR-2011, integrated into UniProtKB/TrEMBL. DT 05-APR-2011, sequence version 1. DT 31-MAY-2011, entry version 2. DE SubName: Full=Polymerase PB2; GN Name=PB2; OS Influenza A virus (A/Hong Kong/415742/2009(H1N1)). OC Viruses; ssRNA negative-strand viruses; Orthomyxoviridae; OC Influenzavirus A. OX NCBI_TaxID=735355; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=A/Hong Kong/415742/2009; RX PubMed=20660098; RA Zheng B., Chan K.H., Zhang A.J., Zhou J., Chan C.C., Poon V.K., RA Zhang K., Leung V.H., Jin D.Y., Woo P.C., Chan J.F., To K.K., Chen H., RA Yuen K.Y.; RT "D225G mutation in hemagglutinin of pandemic influenza H1N1 (2009) RT virus enhances virulence in mice."; RL Exp. Biol. Med. (Maywood) 235:981-988(2010). RN [2] RP NUCLEOTIDE SEQUENCE. RC STRAIN=A/Hong Kong/415742/2009; RA Zheng B.J., Chan K.H., Zhang A.J.X., Zhou J., Jin D.Y., Woo P.C.Y., RA Tse H., Chan J.F.W., To K.K.W., Chen H.L., Yuen K.Y.; RL Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases. CC -!- SUBUNIT: Influenza RNA polymerase is composed of three subunits: CC PB1, PB2 and PA (By similarity). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; GU931811; ADD21402.1; -; Viral_cRNA. DR GO; GO:0003723; F:RNA binding; IEA:InterPro. DR GO; GO:0003968; F:RNA-directed RNA polymerase activity; IEA:InterPro. DR InterPro; IPR001591; RNA_pol_PB2_orthomyxovir. DR Pfam; PF00604; Flu_PB2; 1. DR ProDom; PD001667; RNA_pol_PB2_orthomyxovir; 1. PE 3: Inferred from homology; KW mRNA capping; mRNA processing. SQ SEQUENCE 759 AA; 85879 MW; 37964DF830D4BD7A CRC64; MERIKELRDL MSQSRTREIL TKTTVDHMAI IKKYTSGRQE KNPALRMKWM MAMRYPITAD KRIMDMIPER NEQGQTLWSK TNDAGSDRVM VSPLAVTWWN RNGSTTSTVH YPKVYKTYFE KVERLKHGTF GPVHFRNQVK IRRRVDTNPG HADLSAKEAQ DVIMEVVFPN EVGARILTSE SQLAITKEKK EELQDCKIAP LMVAYMLERE LVRKTRFLPV AGGTGSVYIE VLHLTQGTCW EQMYTPGGEV RNDDVDQSLI IAARNIVRRA AVSADPLASL LEMCHSTQIG GVRMVDILRQ NPTEEQAVDI CKAAIGLRIS SSFSFGGFTF KRTSGSSVKK EEEVLTGNLQ TLKIRVHEGY EEFTMVGRRA TAILRKATRR LIQLIVSGRD EQSIAEAIIV AMVFSQEDCM IKAVRGDLNF VNRANQRLNP MHQLLRHFQK DAKVLFQNWG IESIDNVMGM IGILPDMTPS TEMSLRGIRV SKMGVDEYSS TERVVVSIDR FLRVRDQRGN VLLSPEEVSE TQGTERLTIT YSSSMMWEIN GPESVLVNTY QWIIRNWEIV KIQWSQDPTM LYNKMEFEPF QSLVPKATRS RYSGFVRTLF QQMRDVLGTF DTVQIIKLLP FAAAPPEQSR MQFSSLTVNV RGSGLRILVR GNSPVFNYNK ATKRLTVLGK DAGALTEDPD EGTSGVESAV LRGFLILGKE DKRYGPALSI NELSNLAKGE KANVLIGQGD VVLVMKRKRN SSILTDSQTA TKRIRMAIN //