ID   E7FFJ5_DANRE            Unreviewed;       591 AA.
AC   E7FFJ5;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   14-MAY-2014, sequence version 2.
DT   03-SEP-2014, entry version 22.
DE   SubName: Full=Uncharacterized protein;
DE   Flags: Fragment;
GN   Name=rpusd2;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   IDENTIFICATION.
RC   STRAIN=Tuebingen;
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen;
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C.,
RA   Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L.,
RA   McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C.,
RA   Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T.,
RA   Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T.,
RA   Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F.,
RA   Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H.,
RA   Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Eliott D., Threadgold G.,
RA   Harden G., Ware D., Mortimer B., Kerry G., Heath P., Phillimore B.,
RA   Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S.,
RA   Griffiths G., Smith M., Glithero R., Howden P., Barker N., Stevens C.,
RA   Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H.,
RA   Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C.,
RA   Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA   McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA   Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA   Humphries M., Sycamore N., Barker D., Saunders D., Wallis J.,
RA   Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S.,
RA   Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R.,
RA   Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R.,
RA   Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R.,
RA   Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A.,
RA   Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M.,
RA   Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M.,
RA   Rudolph-Geiger S., Teucke M., Osoegawa K., Zhu B., Rapp A., Widaa S.,
RA   Langford C., Yang F., Carter N.P., Harrow J., Ning Z., Herrero J.,
RA   Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C.,
RA   Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H.,
RA   Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J.,
RA   Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the
RT   human genome.";
RL   Nature 496:498-503(2013).
CC   -!- SIMILARITY: Belongs to the pseudouridine synthase rluA family.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data.
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DR   EMBL; BX571712; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSDART00000086511; ENSDARP00000080946; ENSDARG00000060992.
DR   KEGG; dre:565088; -.
DR   CTD; 27079; -.
DR   ZFIN; ZDB-GENE-120411-43; rpusd2.
DR   GeneTree; ENSGT00420000029802; -.
DR   OMA; KDCKTTF; -.
DR   OrthoDB; EOG7JDQX4; -.
DR   PhylomeDB; E7FFJ5; -.
DR   TreeFam; TF323255; -.
DR   Bgee; E7FFJ5; -.
DR   GO; GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
DR   InterPro; IPR020103; PsdUridine_synth_cat_dom.
DR   InterPro; IPR006225; PsdUridine_synth_RluC/D.
DR   InterPro; IPR006224; PsdUridine_synth_RluC/D_CS.
DR   InterPro; IPR006145; PsdUridine_synth_RsuA/RluD.
DR   InterPro; IPR002942; S4_RNA-bd.
DR   Pfam; PF00849; PseudoU_synth_2; 1.
DR   SMART; SM00363; S4; 1.
DR   SUPFAM; SSF55120; SSF55120; 2.
DR   TIGRFAMs; TIGR00005; rluA_subfam; 1.
DR   PROSITE; PS01129; PSI_RLU; 1.
DR   PROSITE; PS50889; S4; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Reference proteome.
FT   NON_TER       1      1
SQ   SEQUENCE   591 AA;  67058 MW;  D8C0E57C780BE098 CRC64;
     TRRKCIAKPL NSMVHVWKIT HIQALTLLRF GRRQNSEFIK RVYQNRNVSV ETQRTHCSVL
     NVRRNSTQVE SSKHPVNTHL SLYDMDNKGE EGGGDTDSTV KTSCGKRKNE ETDEAAGQCS
     GRKRKRGGGK QLRPGERYVP PPQKRNTGVS FNQEHFAETS YYFEGGLRKV HPYYFDFKSY
     CKGRWIGKTL LDVFKKEFRA ESLDYYNAAV KEGRIKLNET PVDDLNVVLK NNDLLRNTVH
     RHEPPVCGQP LKLLVDDGEV VVVDKPSSLP VHPCGRYRHN TVIFILGKEK GLVGLHTVHR
     LDRLTSGVLL FARTLEVSKK LDVMVRERQL EKEYVCRVEG EFPEAEVVCE EPILVVSFRV
     GLCRVDPKGK ESRTIFQRLS FNGRSSVVRC RPLTGRTHQI RVHLQFLGFP ILNDPIYGSS
     AWGPNRAKGG LVGMSDEELL EALIEEHRSK ESLHLLDLPD EEVSGKTKCK DGAQGRNEQI
     TAIESSSGSS EVSLDEVKAE SRQVVQQSTS ESVGEINGAR KDKDLASDDA SRTGRSKDFV
     RDHLCGECKI VRPDPTEKEL IMYLHALRYK GPDFEYSTQL PDWAKEDWIQ D
//