ID E6YB95_9MOLU Unreviewed; 339 AA. AC E6YB95; DT 08-MAR-2011, integrated into UniProtKB/TrEMBL. DT 08-MAR-2011, sequence version 1. DT 28-JUN-2023, entry version 32. DE RecName: Full=DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00012418}; DE EC=2.7.7.6 {ECO:0000256|ARBA:ARBA00012418}; DE Flags: Fragment; GN Name=rpoB {ECO:0000313|EMBL:ACZ34217.1}; OS Spiroplasma sp. GSU5400. OC Bacteria; Mycoplasmatota; Mollicutes; Entomoplasmatales; Spiroplasmataceae; OC Spiroplasma. OX NCBI_TaxID=692397 {ECO:0000313|EMBL:ACZ34217.1}; RN [1] {ECO:0000313|EMBL:ACZ34217.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=GSU5400 {ECO:0000313|EMBL:ACZ34217.1}; RA Jandhyam H.L., Bates C.R., Regassa L.B.; RT "Global biodiversity of tabanid-associated Spiroplasma sp."; RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA- CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395; CC EC=2.7.7.6; Evidence={ECO:0000256|ARBA:ARBA00024550}; CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; FJ845753; ACZ34217.1; -; Genomic_DNA. DR AlphaFoldDB; E6YB95; -. DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW. DR GO; GO:0003677; F:DNA binding; IEA:InterPro. DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC. DR GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro. DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro. DR Gene3D; 2.40.50.100; -; 1. DR Gene3D; 2.40.50.150; -; 1. DR Gene3D; 3.90.1100.10; -; 1. DR Gene3D; 2.30.150.10; DNA-directed RNA polymerase, beta subunit, external 1 domain; 1. DR Gene3D; 2.40.270.10; DNA-directed RNA polymerase, subunit 2, domain 6; 1. DR InterPro; IPR042107; DNA-dir_RNA_pol_bsu_ext_1_sf. DR InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1. DR InterPro; IPR015712; DNA-dir_RNA_pol_su2. DR InterPro; IPR007120; DNA-dir_RNAP_su2_dom. DR InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf. DR InterPro; IPR014724; RNA_pol_RPB2_OB-fold. DR PANTHER; PTHR20856; DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2; 1. DR PANTHER; PTHR20856:SF20; DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA; 1. DR Pfam; PF10385; RNA_pol_Rpb2_45; 1. DR Pfam; PF00562; RNA_pol_Rpb2_6; 1. DR SUPFAM; SSF64484; beta and beta-prime subunits of DNA dependent RNA-polymerase; 1. PE 4: Predicted; KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478}; KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695}; KW Transcription {ECO:0000256|ARBA:ARBA00023163}; KW Transferase {ECO:0000256|ARBA:ARBA00022679}. FT DOMAIN 14..80 FT /note="DNA-directed RNA polymerase beta subunit external 1" FT /evidence="ECO:0000259|Pfam:PF10385" FT DOMAIN 141..338 FT /note="DNA-directed RNA polymerase subunit 2 hybrid- FT binding" FT /evidence="ECO:0000259|Pfam:PF00562" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:ACZ34217.1" FT NON_TER 339 FT /evidence="ECO:0000313|EMBL:ACZ34217.1" SQ SEQUENCE 339 AA; 37389 MW; 86638A3817406F81 CRC64; YAKINKFGFI ETPYRKVVKG KVLNDEHVYL TADKEKDFIV AQANIQTSKD GKILDESVIA RYRGDDIMAD PMDVDFVDVS PKQIVSIATS CIPFLENDDA NRALMGANMQ RQAVPLINPE SPIVGTGVEF EAARDSGDAV VASEDGIVRY VDSKTITIEG KNGPRSYTLN DFYRSNNGTA ITHLPIVKVG DKVKANDILA DGPSMEKGEL ALGQNVVVAF TTWNGYNFED AVIVSERIVI EDRFTSIHID EYTLERRQTK QGPEEITRDI PNISESHKKH LDNDGIVAIG TEVKVGDILV GKVTPKSQTQ LSPEDKLLHA IFGEKSRNVK DNSLRVPNG //