ID E5FF36_HUMAN Unreviewed; 41 AA. AC E5FF36; DT 08-FEB-2011, integrated into UniProtKB/TrEMBL. DT 08-FEB-2011, sequence version 1. DT 05-SEP-2012, entry version 8. DE SubName: Full=PI3 kinase; DE Flags: Fragment; GN Name=PI3CA; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE. RX PubMed=20976159; DOI=10.1371/journal.pone.0013474; RA Herrmann I., Baeuerle P.A., Friedrich M., Murr A., Filusch S., RA Ruttinger D., Majdoub M.W., Sharma S., Kufer P., Raum T., Munz M.; RT "Highly efficient elimination of colorectal tumor-initiating cells by RT an EpCAM/CD3-bispecific antibody engaging human T cells."; RL PLoS ONE 5:E13474-E13474(2010). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; HM459602; ADQ00185.1; -; Genomic_DNA. DR IPI; IPI00946104; -. DR GO; GO:0030027; C:lamellipodium; IEA:Compara. DR GO; GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:Compara. DR GO; GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IEA:Compara. DR GO; GO:0030295; F:protein kinase activator activity; IEA:Compara. DR GO; GO:0006916; P:anti-apoptosis; IEA:Compara. DR GO; GO:0006006; P:glucose metabolic process; IEA:Compara. DR GO; GO:0044029; P:hypomethylation of CpG island; IEA:Compara. DR GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IEA:Compara. DR GO; GO:0045860; P:positive regulation of protein kinase activity; IEA:GOC. DR GO; GO:0043491; P:protein kinase B signaling cascade; IEA:Compara. DR GO; GO:0006468; P:protein phosphorylation; IEA:Compara. DR GO; GO:2000653; P:regulation of genetic imprinting; IEA:Compara. DR GO; GO:0040014; P:regulation of multicellular organism growth; IEA:Compara. DR Gene3D; G3DSA:1.25.40.70; PI3Ka; 1. DR InterPro; IPR015433; PI_Kinase. DR InterPro; IPR001263; PInositide-3_kin_accessory_dom. DR PANTHER; PTHR10048; PI_Kinase; 1. PE 4: Predicted; KW Kinase. FT NON_TER 1 1 FT NON_TER 41 41 SQ SEQUENCE 41 AA; 4920 MW; D44E7927B7F995FF CRC64; SNRLARDNEL RENDKEQLKA ISTRDPLSEI TXQEKDFLWX H //