ID E5FF36_HUMAN Unreviewed; 41 AA. AC E5FF36; DT 08-FEB-2011, integrated into UniProtKB/TrEMBL. DT 08-FEB-2011, sequence version 1. DT 24-JUL-2024, entry version 41. DE SubName: Full=PI3 kinase {ECO:0000313|EMBL:ADQ00185.1}; DE Flags: Fragment; GN Name=PI3CA {ECO:0000313|EMBL:ADQ00185.1}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. OX NCBI_TaxID=9606 {ECO:0000313|EMBL:ADQ00185.1}; RN [1] {ECO:0000313|EMBL:ADQ00185.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=20976159; DOI=10.1371/journal.pone.0013474; RA Herrmann I., Baeuerle P.A., Friedrich M., Murr A., Filusch S., RA Ruttinger D., Majdoub M.W., Sharma S., Kufer P., Raum T., Munz M.; RT "Highly efficient elimination of colorectal tumor-initiating cells by an RT EpCAM/CD3-bispecific antibody engaging human T cells."; RL PLoS ONE 5:E13474-E13474(2010). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; HM459602; ADQ00185.1; -; Genomic_DNA. DR PeptideAtlas; E5FF36; -. DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW. DR Gene3D; 1.25.40.70; Phosphatidylinositol 3-kinase, accessory domain (PIK); 1. DR InterPro; IPR042236; PI3K_accessory_sf. PE 4: Predicted; KW Kinase {ECO:0000313|EMBL:ADQ00185.1}; KW Transferase {ECO:0000313|EMBL:ADQ00185.1}. FT REGION 1..27 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 1..22 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:ADQ00185.1" FT NON_TER 41 FT /evidence="ECO:0000313|EMBL:ADQ00185.1" SQ SEQUENCE 41 AA; 4920 MW; D44E7927B7F995FF CRC64; SNRLARDNEL RENDKEQLKA ISTRDPLSEI TXQEKDFLWX H //