ID E5FF36_HUMAN Unreviewed; 41 AA. AC E5FF36; DT 08-FEB-2011, integrated into UniProtKB/TrEMBL. DT 08-FEB-2011, sequence version 1. DT 08-JUN-2016, entry version 24. DE SubName: Full=PI3 kinase {ECO:0000313|EMBL:ADQ00185.1}; DE Flags: Fragment; GN Name=PI3CA {ECO:0000313|EMBL:ADQ00185.1}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606 {ECO:0000313|EMBL:ADQ00185.1}; RN [1] {ECO:0000313|EMBL:ADQ00185.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=20976159; DOI=10.1371/journal.pone.0013474; RA Herrmann I., Baeuerle P.A., Friedrich M., Murr A., Filusch S., RA Ruttinger D., Majdoub M.W., Sharma S., Kufer P., Raum T., Munz M.; RT "Highly efficient elimination of colorectal tumor-initiating cells by RT an EpCAM/CD3-bispecific antibody engaging human T cells."; RL PLoS ONE 5:E13474-E13474(2010). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; HM459602; ADQ00185.1; -; Genomic_DNA. DR UniGene; Hs.553498; -. DR UniGene; Hs.715194; -. DR STRING; 9606.ENSP00000263967; -. DR PaxDb; E5FF36; -. DR eggNOG; KOG0904; Eukaryota. DR eggNOG; COG5032; LUCA. DR GO; GO:0005622; C:intracellular; IEA:GOC. DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW. DR GO; GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. DR GO; GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro. DR Gene3D; 1.25.40.70; -; 1. DR InterPro; IPR015433; PI_Kinase. DR InterPro; IPR001263; PInositide-3_kin_accessory_dom. DR PANTHER; PTHR10048; PTHR10048; 1. PE 4: Predicted; KW Kinase {ECO:0000313|EMBL:ADQ00185.1}; KW Transferase {ECO:0000313|EMBL:ADQ00185.1}. FT NON_TER 1 1 {ECO:0000313|EMBL:ADQ00185.1}. FT NON_TER 41 41 {ECO:0000313|EMBL:ADQ00185.1}. SQ SEQUENCE 41 AA; 4920 MW; D44E7927B7F995FF CRC64; SNRLARDNEL RENDKEQLKA ISTRDPLSEI TXQEKDFLWX H //