ID   E3T1W4_PIG              Unreviewed;       459 AA.
AC   E3T1W4;
DT   11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT   11-JAN-2011, sequence version 1.
DT   05-APR-2011, entry version 4.
DE   RecName: Full=NADH-ubiquinone oxidoreductase chain 4;
DE            EC=1.6.5.3;
GN   Name=ND4;
OS   Sus scrofa taiwanensis.
OG   Mitochondrion.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;
OC   Sus.
OX   NCBI_TaxID=310261;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RA   Ju Y.T., Wu C.Y., Jiang Y.N.;
RT   "Intra-population genetic structure of Lan-Yu pig (Sus scrofa) by
RT   analysis of mitochondrial genomic sequences.";
RL   Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Core subunit of the mitochondrial membrane respiratory
CC       chain NADH dehydrogenase (Complex I) that is believed to belong to
CC       the minimal assembly required for catalysis. Complex I functions
CC       in the transfer of electrons from NADH to the respiratory chain.
CC       The immediate electron acceptor for the enzyme is believed to be
CC       ubiquinone (By similarity).
CC   -!- CATALYTIC ACTIVITY: NADH + ubiquinone = NAD(+) + ubiquinol.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion membrane; Multi-pass membrane
CC       protein (By similarity).
CC   -!- SIMILARITY: Belongs to the complex I subunit 4 family.
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DR   EMBL; GU147934; ACZ44406.1; -; Genomic_DNA.
DR   RefSeq; YP_004021584.1; NC_014692.1.
DR   GeneID; 9978381; -.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0070469; C:respiratory chain; IEA:UniProtKB-KW.
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:EC.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; IEA:InterPro.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
DR   InterPro; IPR010227; NADH_Q_OxRdtase_chainM/4.
DR   InterPro; IPR001750; NADH_UbQ/plastoQ_OxRdtase.
DR   InterPro; IPR003918; NADH_UbQ_OxRdtase.
DR   InterPro; IPR000260; NADH_UbQ_OxRdtase_chain4_N.
DR   Pfam; PF00361; Oxidored_q1; 1.
DR   Pfam; PF01059; Oxidored_q5_N; 1.
DR   PRINTS; PR01437; NUOXDRDTASE4.
DR   TIGRFAMs; TIGR01972; NDH_I_M; 1.
PE   3: Inferred from homology;
KW   Electron transport; Membrane; Mitochondrion; NAD; Oxidoreductase;
KW   Respiratory chain; Transmembrane; Transmembrane helix; Transport;
KW   Ubiquinone.
SQ   SEQUENCE   459 AA;  51863 MW;  57ED6F89388E8935 CRC64;
     MLKIIIPTTM LLPMTWMSKH NMIWINATVH SLLISLISLS LLNQLGENSL NFSLTFFSDS
     LSAPLLVLTT WLLPLMLMAS QSHLSKETTT RKKLYITMLI LLQLFLIMTF TATELILFYI
     LFEATLVPTL IIITRWGNQT ERLNAGLYFL FYTLAGSLPL LVALVYIQNT TGSLNFLIIH
     YWSHPLSNSW SNIFMWLACI MAFMVKMPLY GLHLWLPKAH VEAPIAGSMV LAAVLLKLGG
     YGMMRITTIL NPLTNYMAYP FLMLSMWGMI MTSSICLRQT DLKSLIAYSS VSHMALVIVA
     IMIQTPWSFM GATALMIAHG LTSSMLFCLA NTNYERVHSR TMILARGLQT LLPLMATWWL
     MASLTNLALP PSINLIGELF IITASFSWSN ITIILMGMNM MITALYSLYM LIITQRGKYT
     HHINNIKPSF TRENALMALH ILPLLLLTLN PKMILGPLY
//