ID   E3T1W4_PIG              Unreviewed;       459 AA.
AC   E3T1W4;
DT   11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT   11-JAN-2011, sequence version 1.
DT   11-NOV-2015, entry version 24.
DE   RecName: Full=NADH-ubiquinone oxidoreductase chain 4 {ECO:0000256|RuleBase:RU003297, ECO:0000256|SAAS:SAAS00248472};
DE            EC=1.6.5.3 {ECO:0000256|RuleBase:RU003297, ECO:0000256|SAAS:SAAS00248467};
GN   Name=ND4 {ECO:0000313|EMBL:ACZ44406.1};
OS   Sus scrofa taiwanensis.
OG   Mitochondrion {ECO:0000313|EMBL:ACZ44406.1}.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;
OC   Sus.
OX   NCBI_TaxID=310261 {ECO:0000313|EMBL:ACZ44406.1};
RN   [1] {ECO:0000313|EMBL:ACZ44406.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Ju Y.T., Wu C.Y., Jiang Y.N.;
RT   "Intra-population genetic structure of Lan-Yu pig (Sus scrofa) by
RT   analysis of mitochondrial genomic sequences.";
RL   Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: NADH + ubiquinone + 5 H(+)(In) = NAD(+) +
CC       ubiquinol + 4 H(+)(Out). {ECO:0000256|RuleBase:RU003297}.
CC   -!- SIMILARITY: Belongs to the complex I subunit 4 family.
CC       {ECO:0000256|RuleBase:RU003297}.
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DR   EMBL; GU147934; ACZ44406.1; -; Genomic_DNA.
DR   RefSeq; YP_004021584.1; NC_014692.1.
DR   GeneID; 9978381; -.
DR   CTD; 4538; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-KW.
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; IEA:InterPro.
DR   InterPro; IPR000260; NADH4_N.
DR   InterPro; IPR010227; NADH_Q_OxRdtase_chainM/4.
DR   InterPro; IPR003918; NADH_UbQ_OxRdtase.
DR   InterPro; IPR001750; ND/Mrp_mem.
DR   Pfam; PF01059; Oxidored_q5_N; 1.
DR   Pfam; PF00361; Proton_antipo_M; 1.
DR   PRINTS; PR01437; NUOXDRDTASE4.
DR   TIGRFAMs; TIGR01972; NDH_I_M; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAAS:SAAS00307124, ECO:0000256|SAM:Phobius};
KW   Mitochondrion {ECO:0000256|RuleBase:RU000318,
KW   ECO:0000313|EMBL:ACZ44406.1};
KW   NAD {ECO:0000256|RuleBase:RU000317, ECO:0000256|SAAS:SAAS00307154};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU000317,
KW   ECO:0000256|SAAS:SAAS00307100};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00307080,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00307085,
KW   ECO:0000256|SAM:Phobius};
KW   Ubiquinone {ECO:0000256|RuleBase:RU000318,
KW   ECO:0000256|SAAS:SAAS00292518}.
FT   TRANSMEM     21     41       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     61     80       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     92    110       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    116    133       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    145    167       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    193    216       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    223    244       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    256    277       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    284    303       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    309    330       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    351    369       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    389    414       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    435    455       Helical. {ECO:0000256|SAM:Phobius}.
SQ   SEQUENCE   459 AA;  51863 MW;  57ED6F89388E8935 CRC64;
     MLKIIIPTTM LLPMTWMSKH NMIWINATVH SLLISLISLS LLNQLGENSL NFSLTFFSDS
     LSAPLLVLTT WLLPLMLMAS QSHLSKETTT RKKLYITMLI LLQLFLIMTF TATELILFYI
     LFEATLVPTL IIITRWGNQT ERLNAGLYFL FYTLAGSLPL LVALVYIQNT TGSLNFLIIH
     YWSHPLSNSW SNIFMWLACI MAFMVKMPLY GLHLWLPKAH VEAPIAGSMV LAAVLLKLGG
     YGMMRITTIL NPLTNYMAYP FLMLSMWGMI MTSSICLRQT DLKSLIAYSS VSHMALVIVA
     IMIQTPWSFM GATALMIAHG LTSSMLFCLA NTNYERVHSR TMILARGLQT LLPLMATWWL
     MASLTNLALP PSINLIGELF IITASFSWSN ITIILMGMNM MITALYSLYM LIITQRGKYT
     HHINNIKPSF TRENALMALH ILPLLLLTLN PKMILGPLY
//