ID   E2RCJ5_CANLF            Unreviewed;      1214 AA.
AC   E2RCJ5;
DT   30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2010, sequence version 1.
DT   28-FEB-2018, entry version 50.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCAFP00000014536};
GN   Name=MMRN1 {ECO:0000313|Ensembl:ENSCAFP00000014536};
OS   Canis lupus familiaris (Dog) (Canis familiaris).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;
OC   Canis.
OX   NCBI_TaxID=9615 {ECO:0000313|Ensembl:ENSCAFP00000014536, ECO:0000313|Proteomes:UP000002254};
RN   [1] {ECO:0000313|Ensembl:ENSCAFP00000014536, ECO:0000313|Proteomes:UP000002254}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Boxer {ECO:0000313|Ensembl:ENSCAFP00000014536,
RC   ECO:0000313|Proteomes:UP000002254};
RX   PubMed=16341006; DOI=10.1038/nature04338;
RG   Broad Sequencing Platform;
RA   Lindblad-Toh K., Wade C.M., Mikkelsen T.S., Karlsson E.K., Jaffe D.B.,
RA   Kamal M., Clamp M., Chang J.L., Kulbokas E.J. III, Zody M.C.,
RA   Mauceli E., Xie X., Breen M., Wayne R.K., Ostrander E.A.,
RA   Ponting C.P., Galibert F., Smith D.R., deJong P.J., Kirkness E.F.,
RA   Alvarez P., Biagi T., Brockman W., Butler J., Chin C.-W., Cook A.,
RA   Cuff J., Daly M.J., DeCaprio D., Gnerre S., Grabherr M., Kellis M.,
RA   Kleber M., Bardeleben C., Goodstadt L., Heger A., Hitte C., Kim L.,
RA   Koepfli K.-P., Parker H.G., Pollinger J.P., Searle S.M.J.,
RA   Sutter N.B., Thomas R., Webber C., Baldwin J., Abebe A.,
RA   Abouelleil A., Aftuck L., Ait-Zahra M., Aldredge T., Allen N., An P.,
RA   Anderson S., Antoine C., Arachchi H., Aslam A., Ayotte L.,
RA   Bachantsang P., Barry A., Bayul T., Benamara M., Berlin A.,
RA   Bessette D., Blitshteyn B., Bloom T., Blye J., Boguslavskiy L.,
RA   Bonnet C., Boukhgalter B., Brown A., Cahill P., Calixte N.,
RA   Camarata J., Cheshatsang Y., Chu J., Citroen M., Collymore A.,
RA   Cooke P., Dawoe T., Daza R., Decktor K., DeGray S., Dhargay N.,
RA   Dooley K., Dooley K., Dorje P., Dorjee K., Dorris L., Duffey N.,
RA   Dupes A., Egbiremolen O., Elong R., Falk J., Farina A., Faro S.,
RA   Ferguson D., Ferreira P., Fisher S., FitzGerald M., Foley K.,
RA   Foley C., Franke A., Friedrich D., Gage D., Garber M., Gearin G.,
RA   Giannoukos G., Goode T., Goyette A., Graham J., Grandbois E.,
RA   Gyaltsen K., Hafez N., Hagopian D., Hagos B., Hall J., Healy C.,
RA   Hegarty R., Honan T., Horn A., Houde N., Hughes L., Hunnicutt L.,
RA   Husby M., Jester B., Jones C., Kamat A., Kanga B., Kells C.,
RA   Khazanovich D., Kieu A.C., Kisner P., Kumar M., Lance K., Landers T.,
RA   Lara M., Lee W., Leger J.-P., Lennon N., Leuper L., LeVine S., Liu J.,
RA   Liu X., Lokyitsang Y., Lokyitsang T., Lui A., Macdonald J., Major J.,
RA   Marabella R., Maru K., Matthews C., McDonough S., Mehta T.,
RA   Meldrim J., Melnikov A., Meneus L., Mihalev A., Mihova T., Miller K.,
RA   Mittelman R., Mlenga V., Mulrain L., Munson G., Navidi A., Naylor J.,
RA   Nguyen T., Nguyen N., Nguyen C., Nguyen T., Nicol R., Norbu N.,
RA   Norbu C., Novod N., Nyima T., Olandt P., O'Neill B., O'Neill K.,
RA   Osman S., Oyono L., Patti C., Perrin D., Phunkhang P., Pierre F.,
RA   Priest M., Rachupka A., Raghuraman S., Rameau R., Ray V., Raymond C.,
RA   Rege F., Rise C., Rogers J., Rogov P., Sahalie J., Settipalli S.,
RA   Sharpe T., Shea T., Sheehan M., Sherpa N., Shi J., Shih D., Sloan J.,
RA   Smith C., Sparrow T., Stalker J., Stange-Thomann N., Stavropoulos S.,
RA   Stone C., Stone S., Sykes S., Tchuinga P., Tenzing P., Tesfaye S.,
RA   Thoulutsang D., Thoulutsang Y., Topham K., Topping I., Tsamla T.,
RA   Vassiliev H., Venkataraman V., Vo A., Wangchuk T., Wangdi T.,
RA   Weiand M., Wilkinson J., Wilson A., Yadav S., Yang S., Yang X.,
RA   Young G., Yu Q., Zainoun J., Zembek L., Zimmer A., Lander E.S.;
RT   "Genome sequence, comparative analysis and haplotype structure of the
RT   domestic dog.";
RL   Nature 438:803-819(2005).
RN   [2] {ECO:0000313|Ensembl:ENSCAFP00000014536}
RP   IDENTIFICATION.
RC   STRAIN=Boxer {ECO:0000313|Ensembl:ENSCAFP00000014536};
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSCAFP00000014536}.
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DR   EMBL; AAEX03016760; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_005639245.1; XM_005639188.2.
DR   ProteinModelPortal; E2RCJ5; -.
DR   STRING; 9615.ENSCAFP00000014536; -.
DR   PaxDb; E2RCJ5; -.
DR   Ensembl; ENSCAFT00000015706; ENSCAFP00000014536; ENSCAFG00000009884.
DR   GeneID; 487858; -.
DR   KEGG; cfa:487858; -.
DR   CTD; 22915; -.
DR   eggNOG; ENOG410IEM1; Eukaryota.
DR   eggNOG; ENOG411182X; LUCA.
DR   GeneTree; ENSGT00660000095560; -.
DR   InParanoid; E2RCJ5; -.
DR   OMA; CACRHPF; -.
DR   OrthoDB; EOG091G00VO; -.
DR   TreeFam; TF336041; -.
DR   Reactome; R-CFA-114608; Platelet degranulation.
DR   Proteomes; UP000002254; Chromosome 32.
DR   Bgee; ENSCAFG00000009884; -.
DR   GO; GO:0031012; C:extracellular matrix; IBA:GO_Central.
DR   GO; GO:0007596; P:blood coagulation; IEA:InterPro.
DR   Gene3D; 2.60.120.40; -; 1.
DR   InterPro; IPR001073; C1q_dom.
DR   InterPro; IPR013032; EGF-like_CS.
DR   InterPro; IPR000742; EGF-like_dom.
DR   InterPro; IPR011489; EMI_domain.
DR   InterPro; IPR033188; MMRN1.
DR   InterPro; IPR008983; Tumour_necrosis_fac-like_dom.
DR   PANTHER; PTHR15427:SF3; PTHR15427:SF3; 1.
DR   Pfam; PF00386; C1q; 1.
DR   Pfam; PF00008; EGF; 1.
DR   Pfam; PF07546; EMI; 1.
DR   PRINTS; PR00007; COMPLEMNTC1Q.
DR   SMART; SM00110; C1Q; 1.
DR   SMART; SM00181; EGF; 1.
DR   SUPFAM; SSF49842; SSF49842; 1.
DR   PROSITE; PS50871; C1Q; 1.
DR   PROSITE; PS00022; EGF_1; 1.
DR   PROSITE; PS01186; EGF_2; 1.
DR   PROSITE; PS50026; EGF_3; 1.
DR   PROSITE; PS51041; EMI; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002254};
KW   Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00076};
KW   EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002254};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     19       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        20   1214       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003163549.
FT   DOMAIN      191    266       EMI. {ECO:0000259|PROSITE:PS51041}.
FT   DOMAIN     1027   1063       EGF-like. {ECO:0000259|PROSITE:PS50026}.
FT   DOMAIN     1082   1214       C1q. {ECO:0000259|PROSITE:PS50871}.
FT   COILED      397    417       {ECO:0000256|SAM:Coils}.
FT   COILED      584    604       {ECO:0000256|SAM:Coils}.
FT   COILED      662    689       {ECO:0000256|SAM:Coils}.
FT   DISULFID   1053   1062       {ECO:0000256|PROSITE-ProRule:PRU00076}.
SQ   SEQUENCE   1214 AA;  137393 MW;  3CB4B95837617DF2 CRC64;
     MKGAGLFILF FSLWNGGFGL IDTTDTWTTP EDASSQENIA SATVSQNKML PTPQITSAEI
     ATIPEARTSE ESLLKSTLPP SETGTPPEAM RSQTLTSTGK TEGLLKLQTP ALPVNPSLQL
     NPRAESVVLT NSTLKFLQTF IRKSNQQAIA PNSIEGSMGN RSPRETYLSR GDSSGSQKTN
     SQKSSFETTR GKNWCAYVHT RLSPTVILDN QVTYIPNGRG PCGWTSGSCP QRSQKISNPV
     YRMQHKIVTS LEWKCCPGFS GAKCQLKAQE EQHLIHSNQA ESHTAVGRET AEKQQQQDCG
     DPAVTQKMTE QMNYQAMKLT LLQKKIDNIS LAVSDVRNTY SSLEGKINED KDREFQSFLK
     GLKSKSINDL VKNIVREQFK IFQNDMQETV AQLFKTISSL SEDLENTRQI IRQVNESVVS
     IAVQQKSVLM QENRPTLTDI LDLKNHIVNI RQEMTFKCEK PIKELEAKQT HLEGALEQEH
     SWNILYYESL NKTLSKMKEV HEQLLSTEQV SDQKGVPTAE SVSRNVTEYM FALHENIKKQ
     GLMMLQMFDD LHIQDTKINN LTIALEMEKE SVRGECEDML SKCRNDFKFQ IKDTEENLQV
     LNQTLAEVLF PMDNKMDKMN EQLNDLTYDM EILQPLLEQG APFRETMVHE QPKEAIATRK
     KVENLTSSVN SLNILIKELS KKHNLLRNEV QSRSDALDRR INEYALEMED GLNNTMTIIN
     NAVDFIQDNY VLKETLSTIQ YNPEVHHQCT QNMETILTFI PQLRYLNDSI QMLVNDNQRY
     NFVLQVAKVL ADIPKDEKLS QSSFQKIYQM FNETTSQVIK YQQNMSYLEE KILSATKISK
     NFETKLQDIE TKITKTLIPY YMSLKKGGVA TNERDQALQM QVLTSRFKAL EAKSIHLSVH
     FTSLNKTLYE VLVMCHNAST RISELNTTIP KQIKSSLPDI QLLQKGLTEF VESITEIKTQ
     IAISNLTWYI NRTLSDSLAN VVRSQKQIKP LLKKPNSLKK PTVNLTTVLI GRNQRNTDNI
     LVPVTEEYSD CSSSPCQNGG TCINGRTSSV CACRHPFTGD NCTIKLVQEN ALAPDFSQGS
     YRYAPMVAFF ASHTYGMTIP GPILFNNLDV NYGASYTPRT GKFRIPYLGV YVFKYTIESF
     SAHISGFLVV DGIDKLAFES ENINSEIRCD RVLTGDALLE LNYGQEVWLR LVKGTIPAKF
     PPATTFSGYL LYRT
//