ID   E2R729_CANFA            Unreviewed;       966 AA.
AC   E2R729;
DT   30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2010, sequence version 1.
DT   22-JUL-2015, entry version 35.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCAFP00000023209};
GN   Name=GANAB {ECO:0000313|Ensembl:ENSCAFP00000023209};
OS   Canis familiaris (Dog) (Canis lupus familiaris).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;
OC   Canis.
OX   NCBI_TaxID=9615 {ECO:0000313|Ensembl:ENSCAFP00000023209, ECO:0000313|Proteomes:UP000002254};
RN   [1] {ECO:0000313|Ensembl:ENSCAFP00000023209, ECO:0000313|Proteomes:UP000002254}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Boxer {ECO:0000313|Ensembl:ENSCAFP00000023209,
RC   ECO:0000313|Proteomes:UP000002254};
RX   PubMed=16341006; DOI=10.1038/nature04338;
RG   Broad Sequencing Platform;
RA   Lindblad-Toh K., Wade C.M., Mikkelsen T.S., Karlsson E.K., Jaffe D.B.,
RA   Kamal M., Clamp M., Chang J.L., Kulbokas E.J. III, Zody M.C.,
RA   Mauceli E., Xie X., Breen M., Wayne R.K., Ostrander E.A.,
RA   Ponting C.P., Galibert F., Smith D.R., deJong P.J., Kirkness E.F.,
RA   Alvarez P., Biagi T., Brockman W., Butler J., Chin C.-W., Cook A.,
RA   Cuff J., Daly M.J., DeCaprio D., Gnerre S., Grabherr M., Kellis M.,
RA   Kleber M., Bardeleben C., Goodstadt L., Heger A., Hitte C., Kim L.,
RA   Koepfli K.-P., Parker H.G., Pollinger J.P., Searle S.M.J.,
RA   Sutter N.B., Thomas R., Webber C., Baldwin J., Abebe A.,
RA   Abouelleil A., Aftuck L., Ait-Zahra M., Aldredge T., Allen N., An P.,
RA   Anderson S., Antoine C., Arachchi H., Aslam A., Ayotte L.,
RA   Bachantsang P., Barry A., Bayul T., Benamara M., Berlin A.,
RA   Bessette D., Blitshteyn B., Bloom T., Blye J., Boguslavskiy L.,
RA   Bonnet C., Boukhgalter B., Brown A., Cahill P., Calixte N.,
RA   Camarata J., Cheshatsang Y., Chu J., Citroen M., Collymore A.,
RA   Cooke P., Dawoe T., Daza R., Decktor K., DeGray S., Dhargay N.,
RA   Dooley K., Dooley K., Dorje P., Dorjee K., Dorris L., Duffey N.,
RA   Dupes A., Egbiremolen O., Elong R., Falk J., Farina A., Faro S.,
RA   Ferguson D., Ferreira P., Fisher S., FitzGerald M., Foley K.,
RA   Foley C., Franke A., Friedrich D., Gage D., Garber M., Gearin G.,
RA   Giannoukos G., Goode T., Goyette A., Graham J., Grandbois E.,
RA   Gyaltsen K., Hafez N., Hagopian D., Hagos B., Hall J., Healy C.,
RA   Hegarty R., Honan T., Horn A., Houde N., Hughes L., Hunnicutt L.,
RA   Husby M., Jester B., Jones C., Kamat A., Kanga B., Kells C.,
RA   Khazanovich D., Kieu A.C., Kisner P., Kumar M., Lance K., Landers T.,
RA   Lara M., Lee W., Leger J.-P., Lennon N., Leuper L., LeVine S., Liu J.,
RA   Liu X., Lokyitsang Y., Lokyitsang T., Lui A., Macdonald J., Major J.,
RA   Marabella R., Maru K., Matthews C., McDonough S., Mehta T.,
RA   Meldrim J., Melnikov A., Meneus L., Mihalev A., Mihova T., Miller K.,
RA   Mittelman R., Mlenga V., Mulrain L., Munson G., Navidi A., Naylor J.,
RA   Nguyen T., Nguyen N., Nguyen C., Nguyen T., Nicol R., Norbu N.,
RA   Norbu C., Novod N., Nyima T., Olandt P., O'Neill B., O'Neill K.,
RA   Osman S., Oyono L., Patti C., Perrin D., Phunkhang P., Pierre F.,
RA   Priest M., Rachupka A., Raghuraman S., Rameau R., Ray V., Raymond C.,
RA   Rege F., Rise C., Rogers J., Rogov P., Sahalie J., Settipalli S.,
RA   Sharpe T., Shea T., Sheehan M., Sherpa N., Shi J., Shih D., Sloan J.,
RA   Smith C., Sparrow T., Stalker J., Stange-Thomann N., Stavropoulos S.,
RA   Stone C., Stone S., Sykes S., Tchuinga P., Tenzing P., Tesfaye S.,
RA   Thoulutsang D., Thoulutsang Y., Topham K., Topping I., Tsamla T.,
RA   Vassiliev H., Venkataraman V., Vo A., Wangchuk T., Wangdi T.,
RA   Weiand M., Wilkinson J., Wilson A., Yadav S., Yang S., Yang X.,
RA   Young G., Yu Q., Zainoun J., Zembek L., Zimmer A., Lander E.S.;
RT   "Genome sequence, comparative analysis and haplotype structure of the
RT   domestic dog.";
RL   Nature 438:803-819(2005).
RN   [2] {ECO:0000313|Ensembl:ENSCAFP00000023209}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (APR-2011) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 31 family.
CC       {ECO:0000256|RuleBase:RU361185}.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSCAFP00000023209}.
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DR   RefSeq; XP_540905.2; XM_540905.4.
DR   STRING; 9615.ENSCAFP00000023209; -.
DR   Ensembl; ENSCAFT00000025009; ENSCAFP00000023209; ENSCAFG00000015767.
DR   GeneID; 483784; -.
DR   CTD; 23193; -.
DR   GeneTree; ENSGT00760000119229; -.
DR   InParanoid; E2R729; -.
DR   OMA; VAWWQEN; -.
DR   TreeFam; TF300337; -.
DR   Reactome; REACT_301256; Calnexin/calreticulin cycle.
DR   Reactome; REACT_346016; N-glycan trimming in the ER and Calnexin/Calreticulin cycle.
DR   NextBio; 20858137; -.
DR   Proteomes; UP000002254; Chromosome 18.
DR   GO; GO:0070062; C:extracellular exosome; IEA:Ensembl.
DR   GO; GO:0017177; C:glucosidase II complex; IEA:Ensembl.
DR   GO; GO:0016020; C:membrane; IEA:Ensembl.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IEA:Ensembl.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   InterPro; IPR011013; Gal_mutarotase_SF_dom.
DR   InterPro; IPR000322; Glyco_hydro_31.
DR   InterPro; IPR030458; Glyco_hydro_31_AS.
DR   InterPro; IPR030459; Glyco_hydro_31_CS.
DR   InterPro; IPR025887; Glyco_hydro_31_N_dom.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   Pfam; PF13802; Gal_mutarotas_2; 1.
DR   Pfam; PF01055; Glyco_hydro_31; 1.
DR   SUPFAM; SSF51445; SSF51445; 1.
DR   SUPFAM; SSF74650; SSF74650; 2.
DR   PROSITE; PS00129; GLYCOSYL_HYDROL_F31_1; 1.
DR   PROSITE; PS00707; GLYCOSYL_HYDROL_F31_2; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002254};
KW   Glycosidase {ECO:0000256|RuleBase:RU361185};
KW   Hydrolase {ECO:0000256|RuleBase:RU361185};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002254}.
SQ   SEQUENCE   966 AA;  108915 MW;  37AA7961488CD22C CRC64;
     MAAVAAVAAR RRRSGTGLVF TCLGVFLGVT LAVDRSNFKT CEESSFCKRQ RSLRPGLSPY
     RALLDSLQLG PDALTVHLIN EITKVVLVLE LQGLQKNMTR IRIDELEPRR PRYRVPDVLV
     ADPPTSRLSV SGRDDNSVEL TVAEGPYKII LTAQPFRLDL LEDRSLLLSV NARGLLDFEH
     QRAPRVPFSD KVSLTLGSIW DKIKNLFSRQ GSKDPAEGGG AQPEEAPGDG DKPEETQGKA
     EKDEPGAWEE TFKTHSDSKP YGPTSVGLDF SLPGMEHVYG IPEHADNLRL KVTEGGEPYR
     LYNLDVFQYE LYNPMALYGS VPVLLAHSPH RDLGIFWLNA AETWVDISSN TAGKTLFGKM
     LDYLQGSGET PQTDVRWMSE SGIIDVFLLL GPSVSDVFRQ YASLTGTQAL PPLFSLGYHQ
     SRWNYRDEAD VLEVDQGFDD HNLPCDVIWL DIEHADGKRY FTWDPSRFPQ PLTMLQHLAS
     KRRKLVTIVD PHIKVDSGYR VHEELQSRGL YVKTRDGSDY EGWCWPGAAG YPDFTNPTMR
     AWWANMFSFD NYEGSAPNLY VWNDMNEPSV FNGPEVTMLK DAQHYGSWEH RDVHNIYGFY
     VHMATADGLV LRSGGLERPF VLSRAFFAGS QRFGAVWTGD NTAEWDHLKI SIPMCLSLGL
     VGLSFCGADV GGFFKNPEPE LLVRWYQMGA YQPFFRAHAH LDTGRREPWL LPTQYHDIIR
     DALGQRYSLL PFWYTLFYQA HREGIPVMRP LWVHYPQDVT TFSIDDQFLL GDALLVHPVS
     DSGAHGVQVY LPGQGEVWYD SQSYQKHYGP QTLYLPVTLS SIPVFQRGGT IIPRWMRVRR
     SSDCMKDDPI TLFVALSPQG TAQGELFLDD GHTFNYQTHH EFLLRRFSFS GNTLVSSSAD
     PKGYFETPVW IERVVIIGAG KPAAVILQTK GSPETRLSFQ HDPETSVLIL RKPGVNVASD
     WSIHLR
//