ID   E2LY62_MONPE            Unreviewed;       325 AA.
AC   E2LY62;
DT   30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2010, sequence version 1.
DT   12-AUG-2020, entry version 43.
DE   RecName: Full=Adenosine kinase {ECO:0000256|ARBA:ARBA00012119};
DE            EC=2.7.1.20 {ECO:0000256|ARBA:ARBA00012119};
DE   Flags: Fragment;
GN   ORFNames=MPER_12242 {ECO:0000313|EMBL:EEB89639.1};
OS   Moniliophthora perniciosa (strain FA553 / isolate CP02) (Witches'-broom
OS   disease fungus) (Marasmius perniciosus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Marasmiaceae; Moniliophthora.
OX   NCBI_TaxID=554373 {ECO:0000313|EMBL:EEB89639.1, ECO:0000313|Proteomes:UP000000741};
RN   [1] {ECO:0000313|EMBL:EEB89639.1, ECO:0000313|Proteomes:UP000000741}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FA553 / isolate CP02 {ECO:0000313|Proteomes:UP000000741};
RX   PubMed=19019209; DOI=10.1186/1471-2164-9-548;
RA   Mondego J.M., Carazzolle M.F., Costa G.G., Formighieri E.F., Parizzi L.P.,
RA   Rincones J., Cotomacci C., Carraro D.M., Cunha A.F., Carrer H., Vidal R.O.,
RA   Estrela R.C., Garcia O., Thomazella D.P., de Oliveira B.V., Pires A.B.,
RA   Rio M.C., Araujo M.R., de Moraes M.H., Castro L.A., Gramacho K.P.,
RA   Goncalves M.S., Neto J.P., Neto A.G., Barbosa L.V., Guiltinan M.J.,
RA   Bailey B.A., Meinhardt L.W., Cascardo J.C., Pereira G.A.;
RT   "A genome survey of Moniliophthora perniciosa gives new insights into
RT   Witches' broom disease of cacao.";
RL   BMC Genomics 9:548-548(2008).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=adenosine + ATP = ADP + AMP + H(+); Xref=Rhea:RHEA:20824,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:16335, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:456215, ChEBI:CHEBI:456216; EC=2.7.1.20;
CC         Evidence={ECO:0000256|ARBA:ARBA00000130};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   -!- PATHWAY: Purine metabolism; AMP biosynthesis via salvage pathway; AMP
CC       from adenosine: step 1/1. {ECO:0000256|ARBA:ARBA00004801}.
CC   -!- SIMILARITY: Belongs to the carbohydrate kinase PfkB family.
CC       {ECO:0000256|ARBA:ARBA00010688}.
CC   -!- SIMILARITY: Belongs to the carbohydrate kinase pfkB family.
CC       {ECO:0000256|ARBA:ARBA00005380}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EEB89639.1}.
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DR   EMBL; ABRE01017251; EEB89639.1; -; Genomic_DNA.
DR   EnsemblFungi; EEB89639; EEB89639; MPER_12242.
DR   KEGG; mpr:MPER_12242; -.
DR   HOGENOM; CLU_045832_1_0_1; -.
DR   InParanoid; E2LY62; -.
DR   KO; K00856; -.
DR   OMA; APFIAQF; -.
DR   UniPathway; UPA00588; UER00659.
DR   Proteomes; UP000000741; Unassembled WGS sequence.
DR   GO; GO:0004001; F:adenosine kinase activity; IEA:EnsemblFungi.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; IEA:EnsemblFungi.
DR   GO; GO:0006166; P:purine ribonucleoside salvage; IEA:InterPro.
DR   Gene3D; 3.40.1190.20; -; 1.
DR   InterPro; IPR001805; Adenokinase.
DR   InterPro; IPR002173; Carboh/pur_kinase_PfkB_CS.
DR   InterPro; IPR011611; PfkB_dom.
DR   InterPro; IPR029056; Ribokinase-like.
DR   Pfam; PF00294; PfkB; 1.
DR   PRINTS; PR00989; ADENOKINASE.
DR   SUPFAM; SSF53613; SSF53613; 1.
DR   PROSITE; PS00584; PFKB_KINASES_2; 1.
PE   3: Inferred from homology;
KW   Kinase {ECO:0000256|ARBA:ARBA00022777};
KW   Purine salvage {ECO:0000256|ARBA:ARBA00022726};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000741};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          23..325
FT                   /note="PfkB"
FT                   /evidence="ECO:0000259|Pfam:PF00294"
FT   NON_TER         325
FT                   /evidence="ECO:0000313|EMBL:EEB89639.1"
SQ   SEQUENCE   325 AA;  34215 MW;  55A6CCFF90A3DB20 CRC64;
     MSYSLFCIGN PLLDIQVTNG EKLLEKYGLK ANDAILAEEK HTPIYDEIVR EHKVTYVAGG
     AAQNAARGAA YILPPDSVVY TGCVGDDDLA EQLKAANKRE GLHQVYQVKK GEKTGACAVV
     ITGHNRSLVT TLRAAEKFEK SHLSSPEVAP LIDGAKAFYV EGYFLTHGTE AIVEVGQKAS
     AAGKVFALNF SAPFIPPLFG AQLQQVLPYT DIAICNESEA EAWASATGHA DPKDLAAVAK
     SIALLPKSNP SRPRIAVITH GAESTILVSS AEPDAPKVIP VHALKDSEIV DTNGAGDAFA
     GGFMGAFVAG KSLDECVEGG HKMGS
//