ID E2LWQ3_MONPE Unreviewed; 380 AA. AC E2LWQ3; DT 30-NOV-2010, integrated into UniProtKB/TrEMBL. DT 30-NOV-2010, sequence version 1. DT 29-MAY-2013, entry version 15. DE RecName: Full=UDP-glucose 6-dehydrogenase; DE EC=1.1.1.22; DE Flags: Fragment; GN ORFNames=MPER_11684; OS Moniliophthora perniciosa (strain FA553 / isolate CP02) OS (Witches'-broom disease fungus) (Marasmius perniciosus). OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; OC Agaricomycetes; Agaricomycetidae; Agaricales; Marasmiaceae; OC mitosporic Marasmiaceae; Moniliophthora. OX NCBI_TaxID=554373; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=FA553 / isolate CP02; RX PubMed=19019209; DOI=10.1186/1471-2164-9-548; RA Mondego J.M., Carazzolle M.F., Costa G.G., Formighieri E.F., RA Parizzi L.P., Rincones J., Cotomacci C., Carraro D.M., Cunha A.F., RA Carrer H., Vidal R.O., Estrela R.C., Garcia O., Thomazella D.P., RA de Oliveira B.V., Pires A.B., Rio M.C., Araujo M.R., de Moraes M.H., RA Castro L.A., Gramacho K.P., Goncalves M.S., Moura Neto J.P., RA Goes Neto A., Barbosa L.V., Guiltinan M.J., Bailey B.A., RA Meinhardt L.W., Cascardo J.C., Pereira G.A.; RT "A genome survey of Moniliophthora perniciosa gives new insights into RT Witches' Broom Disease of cacao."; RL BMC Genomics 9:548-548(2008). CC -!- CATALYTIC ACTIVITY: UDP-glucose + 2 NAD(+) + H(2)O = UDP- CC glucuronate + 2 NADH. CC -!- SIMILARITY: Belongs to the UDP-glucose/GDP-mannose dehydrogenase CC family. CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; ABRE01016750; EEB90148.1; -; Genomic_DNA. DR RefSeq; XP_002389218.1; XM_002389177.1. DR ProteinModelPortal; E2LWQ3; -. DR GeneID; 7924416; -. DR KEGG; mpr:MPER_11684; -. DR KO; K00012; -. DR GO; GO:0051287; F:NAD binding; IEA:InterPro. DR GO; GO:0003979; F:UDP-glucose 6-dehydrogenase activity; IEA:EC. DR Gene3D; 3.40.50.720; -; 2. DR InterPro; IPR008927; 6-PGluconate_DH_C-like. DR InterPro; IPR016040; NAD(P)-bd_dom. DR InterPro; IPR017476; Nucleotide_sugar_DH. DR InterPro; IPR014027; UDP-Glc/GDP-Man_DH_C. DR InterPro; IPR014026; UDP-Glc/GDP-Man_DH_dimer. DR InterPro; IPR001732; UDP-Glc/GDP-Man_DH_N. DR Pfam; PF00984; UDPG_MGDP_dh; 1. DR Pfam; PF03720; UDPG_MGDP_dh_C; 1. DR Pfam; PF03721; UDPG_MGDP_dh_N; 1. DR PIRSF; PIRSF000124; UDPglc_GDPman_dh; 1. DR SMART; SM00984; UDPG_MGDP_dh_C; 1. DR SUPFAM; SSF48179; 6DGDH_C_like; 1. DR SUPFAM; SSF52413; UDP-Glc/GDP-Man_DH_C; 1. DR TIGRFAMs; TIGR03026; NDP-sugDHase; 1. PE 3: Inferred from homology; KW Complete proteome; NAD; Oxidoreductase. FT NON_TER 380 380 SQ SEQUENCE 380 AA; 41957 MW; 0D571A13D99D787F CRC64; MYTRGRLIFV SVNTPTKKTG VGAGFAADLN YVELATRRIA AVANTSKIVV EKSTVPCRTA ESMRTILEAN SKPNCRFDIL SNPEFLAEGT AIQDLFKPDR VLIGSLQTPE GIAACKSLSE IYANWVSEDR ILAVGLWSSE LTKLAANAML AQRISSVNAL SAICEATGAN IDEVAHAVGY DSRIGPKFLK ASVGFGGSCF QKDILNLVYL SESCHLPEVA AYWRQVVELN EYQKRRFSKR VVDTLFNTIT GKRIAVLGFA FKADTGDTRE SAAITLIKDF QNERALVNIY DPQVPHDQIW TDLSEASPHL PLETIRKQVT ICGSALEACK NAEAVVISTE WKEFKAIDWE MVYQNMNKPA FVFDGRLLVD AEKLTKIGFK //