ID E2IK92_9HIV1 Unreviewed; 210 AA. AC E2IK92; DT 30-NOV-2010, integrated into UniProtKB/TrEMBL. DT 30-NOV-2010, sequence version 1. DT 29-SEP-2021, entry version 23. DE SubName: Full=Pol protein {ECO:0000313|EMBL:ADN95417.1}; DE Flags: Fragment; GN Name=pol {ECO:0000313|EMBL:ADN95417.1}; OS Human immunodeficiency virus 1. OC Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes; OC Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus. OX NCBI_TaxID=11676 {ECO:0000313|EMBL:ADN95417.1}; OH NCBI_TaxID=9606; Homo sapiens (Human). RN [1] {ECO:0000313|EMBL:ADN95417.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=A 14888 M6 {ECO:0000313|EMBL:ADN95417.1}; RX PubMed=20854169; DOI=10.1089/aid.2010.0037; RA Zolfo M., Schapiro J.M., Phan V., Koole O., Thai S., Vekemans M., RA Fransen K., Lynen L.; RT "Genotypic Impact of Prolonged Detectable HIV Type 1 RNA Viral Load after RT HAART Failure in a CRF01_AE-Infected Cohort."; RL AIDS Res. Hum. Retroviruses 27:727-735(2011). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; HM565577; ADN95417.1; -; Genomic_RNA. DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW. DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW. DR Gene3D; 3.30.70.270; -; 1. DR InterPro; IPR043502; DNA/RNA_pol_sf. DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase. DR InterPro; IPR000477; RT_dom. DR Pfam; PF00078; RVT_1; 1. DR SUPFAM; SSF56672; SSF56672; 1. DR PROSITE; PS50878; RT_POL; 1. PE 4: Predicted; KW Endonuclease {ECO:0000256|ARBA:ARBA00022759}; KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}; KW Nuclease {ECO:0000256|ARBA:ARBA00022722}; KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695}; KW RNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022918}; KW Transferase {ECO:0000256|ARBA:ARBA00022679}. FT DOMAIN 7..197 FT /note="Reverse transcriptase" FT /evidence="ECO:0000259|PROSITE:PS50878" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:ADN95417.1" FT NON_TER 210 FT /evidence="ECO:0000313|EMBL:ADN95417.1" SQ SEQUENCE 210 AA; 24581 MW; CB416A99E11BC75F CRC64; CEEMEKEGKI SKIGPENPYN TPVFAIKKKD STKWRKLVDF RELNKRTQDF WEVQLGIPHP AGLKKKKSIT VLDVGDAYFS XPLDESFRKY TAFTIPSINN ETPGIRYQYN VLPQGWKGSP AIFQCSMTKI LEPFRIKNPE IVIYQYMDDL YVGSDLEIGQ HRXKIEELRA HLLSWGFTTP DKKHQKEPPF LWMGYELHPD RWTVQPIELP //