ID E1JIN6_DROME Unreviewed; 2716 AA. AC E1JIN6; DT 30-NOV-2010, integrated into UniProtKB/TrEMBL. DT 30-NOV-2010, sequence version 1. DT 28-MAR-2018, entry version 72. DE SubName: Full=Osa, isoform D {ECO:0000313|EMBL:ACZ94935.1}; GN Name=osa {ECO:0000313|EMBL:ACZ94935.1, GN ECO:0000313|FlyBase:FBgn0261885}; GN Synonyms=4H {ECO:0000313|EMBL:ACZ94935.1}, anon-WO0118547.314 GN {ECO:0000313|EMBL:ACZ94935.1}, anon-WO0172774.126 GN {ECO:0000313|EMBL:ACZ94935.1}, C819 {ECO:0000313|EMBL:ACZ94935.1}, GN Dmel\CG7467 {ECO:0000313|EMBL:ACZ94935.1}, E(E2F)3C GN {ECO:0000313|EMBL:ACZ94935.1}, eld {ECO:0000313|EMBL:ACZ94935.1}, GN en(lz)4F {ECO:0000313|EMBL:ACZ94935.1}, eyelid GN {ECO:0000313|EMBL:ACZ94935.1}, l(3)00090 GN {ECO:0000313|EMBL:ACZ94935.1}, l(3)04539 GN {ECO:0000313|EMBL:ACZ94935.1}, l(3)j9C3 {ECO:0000313|EMBL:ACZ94935.1}, GN OSA {ECO:0000313|EMBL:ACZ94935.1}, Osa {ECO:0000313|EMBL:ACZ94935.1}, GN p300 {ECO:0000313|EMBL:ACZ94935.1}; GN ORFNames=CG7467 {ECO:0000313|EMBL:ACZ94935.1, GN ECO:0000313|FlyBase:FBgn0261885}, Dmel_CG7467 GN {ECO:0000313|EMBL:ACZ94935.1}; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227 {ECO:0000313|EMBL:ACZ94935.1, ECO:0000313|Proteomes:UP000000803}; RN [1] {ECO:0000313|EMBL:ACZ94935.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=10731132; DOI=10.1126/science.287.5461.2185; RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., RA Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., RA Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., RA Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., RA Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., RA Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., RA Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., RA Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., RA Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., RA de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., RA Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., RA Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., RA Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., RA Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., RA Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., RA Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., RA Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., RA Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., RA Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., RA Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., RA Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., RA Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., RA Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., RA Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., RA Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., RA Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., RA Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., RA Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., RA Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., RA Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., RA Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., RA Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.; RT "The genome sequence of Drosophila melanogaster."; RL Science 287:2185-2195(2000). RN [2] {ECO:0000313|EMBL:ACZ94935.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537568; RA Celniker S.E., Wheeler D.A., Kronmiller B., Carlson J.W., Halpern A., RA Patel S., Adams M., Champe M., Dugan S.P., Frise E., Hodgson A., RA George R.A., Hoskins R.A., Laverty T., Muzny D.M., Nelson C.R., RA Pacleb J.M., Park S., Pfeiffer B.D., Richards S., Sodergren E.J., RA Svirskas R., Tabor P.E., Wan K., Stapleton M., Sutton G.G., Venter C., RA Weinstock G., Scherer S.E., Myers E.W., Gibbs R.A., Rubin G.M.; RT "Finishing a whole-genome shotgun: release 3 of the Drosophila RT melanogaster euchromatic genome sequence."; RL Genome Biol. 3:RESEARCH0079-RESEARCH0079(2002). RN [3] {ECO:0000313|EMBL:ACZ94935.1, ECO:0000313|Proteomes:UP000000803} RP GENOME REANNOTATION. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083; RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., RA Smith C.D., Tupy J.L., Whitfied E.J., Bayraktaroglu L., Berman B.P., RA Bettencourt B.R., Celniker S.E., de Grey A.D., Drysdale R.A., RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., RA Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., RA Lewis S.E.; RT "Annotation of the Drosophila melanogaster euchromatic genome: a RT systematic review."; RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002). RN [4] {ECO:0000313|EMBL:ACZ94935.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537573; RA Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R., RA Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., RA Ashburner M., Celniker S.E.; RT "The transposable elements of the Drosophila melanogaster euchromatin: RT a genomics perspective."; RL Genome Biol. 3:RESEARCH0084.1-RESEARCH0084.20(2002). RN [5] {ECO:0000313|EMBL:ACZ94935.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537574; RA Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A., RA Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G., RA Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M., RA Karpen G.H.; RT "Heterochromatic sequences in a Drosophila whole-genome shotgun RT assembly."; RL Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002). RN [6] {ECO:0000313|EMBL:ACZ94935.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=16110336; DOI=10.1371/journal.pcbi.0010022; RA Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D., RA Ashburner M., Anxolabehere D.; RT "Combined evidence annotation of transposable elements in genome RT sequences."; RL PLoS Comput. Biol. 1:166-175(2005). RN [7] {ECO:0000313|EMBL:ACZ94935.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=17569856; DOI=10.1126/science.1139815; RA Smith C.D., Shu S., Mungall C.J., Karpen G.H.; RT "The Release 5.1 annotation of Drosophila melanogaster RT heterochromatin."; RL Science 316:1586-1591(2007). RN [8] {ECO:0000313|EMBL:ACZ94935.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=17569867; DOI=10.1126/science.1139816; RA Hoskins R.A., Carlson J.W., Kennedy C., Acevedo D., Evans-Holm M., RA Frise E., Wan K.H., Park S., Mendez-Lago M., Rossi F., Villasante A., RA Dimitri P., Karpen G.H., Celniker S.E.; RT "Sequence finishing and mapping of Drosophila melanogaster RT heterochromatin."; RL Science 316:1625-1628(2007). CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|SAAS:SAAS00704572}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AE014297; ACZ94935.1; -; Genomic_DNA. DR RefSeq; NP_001163639.1; NM_001170168.2. DR RefSeq; NP_524392.2; NM_079668.3. DR UniGene; Dm.2989; -. DR ProteinModelPortal; E1JIN6; -. DR SMR; E1JIN6; -. DR PRIDE; E1JIN6; -. DR EnsemblMetazoa; FBtr0089581; FBpp0088543; FBgn0261885. DR EnsemblMetazoa; FBtr0089582; FBpp0088544; FBgn0261885. DR EnsemblMetazoa; FBtr0301487; FBpp0290702; FBgn0261885. DR EnsemblMetazoa; FBtr0335024; FBpp0307030; FBgn0261885. DR EnsemblMetazoa; FBtr0335025; FBpp0307031; FBgn0261885. DR GeneID; 42130; -. DR KEGG; dme:Dmel_CG7467; -. DR CTD; 42130; -. DR FlyBase; FBgn0261885; osa. DR eggNOG; KOG2510; Eukaryota. DR eggNOG; ENOG410Y034; LUCA. DR KO; K11653; -. DR OMA; YSTMVRF; -. DR OrthoDB; EOG091G00GP; -. DR PhylomeDB; E1JIN6; -. DR ChiTaRS; osa; fly. DR GenomeRNAi; 42130; -. DR Proteomes; UP000000803; Chromosome 3R. DR Bgee; FBgn0261885; -. DR ExpressionAtlas; E1JIN6; differential. DR GO; GO:0070603; C:SWI/SNF superfamily-type complex; IEA:InterPro. DR GO; GO:0003677; F:DNA binding; IEA:InterPro. DR GO; GO:0006338; P:chromatin remodeling; IEA:InterPro. DR Gene3D; 1.10.150.60; -; 1. DR InterPro; IPR001606; ARID_dom. DR InterPro; IPR036431; ARID_dom_sf. DR InterPro; IPR016024; ARM-type_fold. DR InterPro; IPR021906; BAF250/Osa. DR InterPro; IPR033388; BAF250_C. DR PANTHER; PTHR12656; PTHR12656; 7. DR Pfam; PF01388; ARID; 1. DR Pfam; PF12031; BAF250_C; 1. DR SMART; SM00501; BRIGHT; 1. DR SUPFAM; SSF46774; SSF46774; 1. DR SUPFAM; SSF48371; SSF48371; 1. DR PROSITE; PS51011; ARID; 1. PE 1: Evidence at protein level; KW Coiled coil {ECO:0000256|SAM:Coils}; KW Complete proteome {ECO:0000313|Proteomes:UP000000803}; KW Nucleus {ECO:0000256|SAAS:SAAS00704574}; KW Proteomics identification {ECO:0000213|PeptideAtlas:E1JIN6}; KW Reference proteome {ECO:0000313|Proteomes:UP000000803}. FT DOMAIN 1000 1091 ARID. {ECO:0000259|PROSITE:PS51011}. FT COILED 1852 1872 {ECO:0000256|SAM:Coils}. SQ SEQUENCE 2716 AA; 284064 MW; EFAE76CB51C7C675 CRC64; MNEKIKSPQT QQQQQGGAPA PAATPPSAGA APGAATPPTS GPPTPNNNSN NGSDPSIQQQ QQNVAPHPYG APPPPGSGPG GPPGPDPAAV MHYHHLHQQQ QQHPPPPHMQ QQQHHGGPAP PPPGGAPEHA PGVKEEYTHL PPPHPHPAYG RYHADPNMDP YRYGQPLPGG KPPQQQQPHP QQQPPQQPGP GGSPNRPPQQ RYIPGQPPQG PTPTLNSLLQ SSNPPPPPQH RYANTYDPQQ AAASAAAAAA AQQQQAGGPP PPGHGPPPPQ HQPSPYGGQQ GGWAPPPRPY SPQLGPSQQY RTPPPTNTSR GQSPYPPAHG QNSGSYPSSP QQQQQQQQQQ QQQAGQQPGG PVPGGPPPGT GQQPPQQNTP PTSQYSPYPQ RYPTPPGLPA GGSNHRTAYS THQYPEPNRP WPGGSSPSPG SGHPLPPASP HHVPPLQQQP PPPPHVSAGG PPPSSSPGHA PSPSPQPSQA SPSPHQELIG QNSNDSSSGG AHSGMGSGPP GTPNPQQVMR PTPSPTGSSG SRSMSPAVAQ NHPISRPASN QSSSGGPMQQ PPVGAGGPPP MPPHPGMPGG PPQQQQSQQQ QASNSASSAS NSPQQTPPPA PPPNQGMNNM ATPPPPPQGA AGGGYPMPPH MHGGYKMGGP GQSPGAQGYP PQQPQQYPPG NYPPRPQYPP GAYATGPPPP PTSQAGAGGA NSMPSGAQAG GYPGRGMPNH TGQYPPYQWV PPSPQQTVPG GAPGGAMVGN HVQGKGTPPP PVVGGPPPPQ GSGSPRPLNY LKQHLQHKGG YGGSPTPPQG PQGYGNGPTG MHPGMPMGPP HHMGPPHGPT NMGPPTSTPP QSQMLQGGQP QGQGASGGPE SGGPEHISQD NGISSSGPTG AAGMHAVTSV VTTGPDGTSM DEVSQQSTLS NASAASGEDP QCTTPKSRKN DPYSQSHLAP PSTSPHPVVM HPGGGPGEEY DMSSPPNWPR PAGSPQVFNH VPVPQEPFRS TITTTKKSDS LCKLYEMDDN PDRRGWLDKL RAFMEERRTP ITACPTISKQ PLDLYRLYIY VKERGGFVEV TKSKTWKDIA GLLGIGASSS AAYTLRKHYT KNLLTFECHF DRGDIDPLPI IQQVEAGSKK KTAKAASVPS PGGGHLDAGT TNSTGSSNSQ DSFPAPPGSA PNAAIDGYPG YPGGSPYPVA SGPQPDYATA GQMQRPPSQN NPQTPHPGAA AAVAAGDNIS VSNPFEDPIA AGGGPGSGTG PGPGQGPGPG AASGGAGAVG AVGGGPQPHP PPPHSPHTAA QQAAGQHQQQ HPQHQHPGLP GPPPPQQQQG QQGQQPPPSV GGGPPPAPQQ HGPGQVPPSP QQHVRPAAGA PYPPGGSGYP TPVSRTPGSP YPSQPGAYGQ YGSSDQYNAT GPPGQPFGQG PGQYPPQNRN MYPPYGPEGE APPTGANQYG PYGSRPYSQP PPGGPQPPTQ TVAGGPPAGG APGAPPSSAY PTGRPSQQDY YQPPPDQSPQ PRRHPDFIKD SQPYPGYNAR PQIYGAWQSG TQQYRPQYPS SPAPQNWGGA PPRGAAPPPG APHGPPIQQP AGVAQWDQHR YPPQQGPPPP PQQQQQPQQQ QQQPPYQQVA GPPGQQPPQA PPQWAQMNPG QTAQSGIAPP GSPLRPPSGP GQQNRMPGMP AQQQQSQQQG GVPQPPPQQA SHGGVPSPGL PQVGPGGMVK PPYAMPPPPS QGVGQQVGQG PPGGMMSQKP PPMPGQAMQQ QPLQQQPPSH QHPHPHQHPQ HQHPHQMPPN QTAPGGYGPP GMPGGGAQLV KKELIFPHDS VESTTPVLYR RKRLMKADVC PVDPWRIFMA MRSGLLTECT WALDVLNVLL FDDSTVQFFG ISNLPGLLTL LLEHFQKNLA EMFDERENEE QSALLAEDAD DDADSGTVMC EKLRTSGRQP RCVRSISSYN RRRHYENMDR SGKDGAGNGS DSEDADEGID LGQVRVQPNP EERSLLLSFT PNYTMVTRKG VPVRIQPAEN DIFVDERQKA WDIDTNRLYE QLEPVGSDAW TYGFTEPDPL DGIIDVFKSE IVNIPFARYI RSDKKGRKRT ELASSSRKPE IKTEENSTEE QTFNKKRRLV SGGSSSSGAH AEGKKSKLTS EEFAQPNAEV KKEPGTADSD CRPVDMDIEA PQQRLTNGVA PCSSTPAIFD PRTTAKDEAR VLQRRRDSSF EDECYTRDEA SLHLVSESQD SLARRCIALS NIFRNLTFVP GNETVLAKST RFLAVLGRLL LLNHEHLRRT PKTRNYDREE DTDFSDSCSS LQGEREWWWD YLITIRENML VAMANIAGHL ELSRYDELIA RPLIDGLLHW AVCPSAHGQD PFPSCGPNSV LSPQRLALEA LCKLCVTDAN VDLVIATPPF SRLEKLCAVL TRHLCRNEDQ VLREFSVNLL HYLAAADSAM ARTVALQSPC ISYLVAFIEQ AEQTALGVAN QHGINYLREN PDSMGTSLDM LRRAAGTLLH LAKHPDNRSL FMQQEQRLLG LVMSHILDQQ VALIISRVLY QVSRGTGPIH SVEFRLLQQR QQQQLRPGPA GKQAASAGGS ATVKAETAST ETSSTEAKPA PAATTAVVND ENSNSSQQLP PAATFNDVSN SSTNSNSCGT ASSNQTNNST TNSSHSSSAI SSQSAITVAA PSAAATGAGS ATAAAIASDQ QQVSKVAAAA AAAAALSNAS AAAAAAAAAA AASVGPPTSS SVSAGAAVAQ PAAPPPTNAG TTTAVA //