ID E1CJT4_HUMAN Unreviewed; 143 AA. AC E1CJT4; DT 30-NOV-2010, integrated into UniProtKB/TrEMBL. DT 30-NOV-2010, sequence version 1. DT 24-JUL-2024, entry version 72. DE SubName: Full=RNA-binding protein 5 variant {ECO:0000313|EMBL:BAJ19019.1}; GN Name=RBM5 variant {ECO:0000313|EMBL:BAJ19019.1}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. OX NCBI_TaxID=9606 {ECO:0000313|EMBL:BAJ19019.1}; RN [1] {ECO:0000313|EMBL:BAJ19019.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=11282995; DOI=10.1093/intimm/13.4.559; RA Takei M., Ishiwata T., Mitamura K., Fujiwara S., Sasaki K., Nishi T., RA Kuga T., Ookubo T., Horie T., Ryu J., Ohi H., Sawada S.; RT "Decreased expression of signaling lymphocytic-activation molecule- RT associated protein (SAP) transcripts in T cells from patients with RT rheumatoid arthritis."; RL Int. Immunol. 13:559-565(2001). RN [2] {ECO:0000313|EMBL:BAJ19019.1} RP NUCLEOTIDE SEQUENCE. RA Sawada S., Takei M.; RT "Possible involvement of Epstein-Barr virus and its regulatory gene in RT rheumatoid synovitis."; RL Autoimmun Rev 0:S69-S71(2004). RN [3] {ECO:0000313|EMBL:BAJ19019.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=15722257; DOI=10.1016/j.autrev.2004.08.034; RA Sawada S., Takei M.; RT "Epstein-Barr virus etiology in rheumatoid synovitis."; RL Autoimmun Rev 4:106-110(2005). RN [4] {ECO:0000313|EMBL:BAJ19019.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=17785286; DOI=10.1196/annals.1398.003; RA Sawada S., Takei M., Ishiwata T., Shiraiwa H., Inomata H., Nozaki T.; RT "SLAM-associated protein solves a mystery of autoimmunity."; RL Ann. N. Y. Acad. Sci. 1109:19-30(2007). RN [5] {ECO:0000313|EMBL:BAJ19019.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=17289546; DOI=10.1016/j.autrev.2006.08.014; RA Sawada S., Takei M., Inomata H., Nozaki T., Shiraiwa H.; RT "What is after cytokine-blocking therapy, a novel therapeutic RT target--synovial Epstein-Barr virus for rheumatoid arthritis."; RL Autoimmun Rev 6:126-130(2007). RN [6] {ECO:0000313|EMBL:BAJ19019.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=17643931; DOI=10.1016/j.autrev.2007.01.015; RA Sawada S., Takei M., Ishiwata T.; RT "SAP discovery: the sword edges--beneficial and harmful."; RL Autoimmun Rev 6:444-449(2007). RN [7] {ECO:0000313|EMBL:BAJ19019.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=18587224; DOI=10.2177/jsci.31.141; RA Takei M., Kitamura N., Shiraiwa H., Inomata H., Nozaki T., Kuwata Y., RA Shiozaki M., Sawada S., Ishiwata T.; RT "The possible curative therapy for rheumatoid arthritis--EBV infection RT control gene SAP and its application."; RL Nihon Rinsho Meneki Gakkai Kaishi 31:141-151(2008). RN [8] {ECO:0000313|EMBL:BAJ19019.1} RP NUCLEOTIDE SEQUENCE. RA Ishiwata T., Sakurada M., Kawabata A., Nakagawa S., Nishi T., Kuga T., RA Sawada S., Takei M., Shibata K., Furuya A.; RT "IgA nephropathy-related DNA ated DNA Patent: CA 2329683."; RL Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases. RN [9] {ECO:0000313|EMBL:BAJ19019.1} RP NUCLEOTIDE SEQUENCE. RA Ishiwata T., Sakurada M., Kawabata A., Nakagawa S., Nishi T., Kuga T., RA Sawada S., Takei M., Shibata K., Furuya A.; RT "IgA nephropathy-related DNA."; RL Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases. RN [10] {ECO:0000313|EMBL:BAJ19019.1} RP NUCLEOTIDE SEQUENCE. RA Furuya A., Ishiwata T., Kawabata A., Kuga T., Nakagawa S., Nishi T., RA Sakurada M., Sawada S., Shibata K., Takei M.; RT "IgA nephropathy-related DNA."; RL Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases. RN [11] {ECO:0000313|EMBL:BAJ19019.1} RP NUCLEOTIDE SEQUENCE. RA Ishiwata T., Sakurada M., Nishimura A., Nakagawa S., Nishi T., Kuga T., RA Sawada S., Takei M., Shibata K., Furuya A.; RT "IgA nephropathy-related gene."; RL Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases. RN [12] {ECO:0000313|EMBL:BAJ19019.1} RP NUCLEOTIDE SEQUENCE. RA Ishiwata T., Sakurada M., Nishimura A., Nakagawa S., Nishi T., Kuga T., RA Sawada S., Takei M.; RT "IgA nephropathy-related gene."; RL Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AB586690; BAJ19019.1; -; mRNA. DR AlphaFoldDB; E1CJT4; -. DR SMR; E1CJT4; -. DR Antibodypedia; 1962; 264 antibodies from 30 providers. DR VEuPathDB; HostDB:ENSG00000003756; -. DR ChiTaRS; RBM5; human. DR ExpressionAtlas; E1CJT4; baseline and differential. DR GO; GO:0005654; C:nucleoplasm; IDA:HPA. DR GO; GO:0003723; F:RNA binding; IEA:TreeGrafter. DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:TreeGrafter. DR Gene3D; 3.30.70.330; -; 1. DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf. DR InterPro; IPR035979; RBD_domain_sf. DR PANTHER; PTHR13948; RNA-BINDING PROTEIN; 1. DR PANTHER; PTHR13948:SF21; RNA-BINDING PROTEIN 5; 1. DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1. PE 2: Evidence at transcript level; KW Nucleus {ECO:0000256|ARBA:ARBA00023242}. FT REGION 1..96 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 120..143 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 143 AA; 17055 MW; 9D5FC205E7B15147 CRC64; MGSDKRVSRT ERSGRYGSII DRDDRDERES RSRRRDSDYK RSSDDRRGDR YDDYRDYDSP ERERERRNSD RSEDGYHSDG DYGEHDYRHD ISDERESKTI MLRGLPITIT ESDIREMMES FEGPQPADVR LMKRKTGESL LSS //