ID E1BM22_BOVIN Unreviewed; 126 AA. AC E1BM22; DT 02-NOV-2010, integrated into UniProtKB/TrEMBL. DT 16-NOV-2011, sequence version 2. DT 29-MAY-2024, entry version 90. DE RecName: Full=Histone H2A/H2B/H3 domain-containing protein {ECO:0000259|Pfam:PF00125}; OS Bos taurus (Bovine). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; OC Bovinae; Bos. OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000046113.3, ECO:0000313|Proteomes:UP000009136}; RN [1] {ECO:0000313|Ensembl:ENSBTAP00000046113.3, ECO:0000313|Proteomes:UP000009136} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000046113.3, RC ECO:0000313|Proteomes:UP000009136}; RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A., RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C., RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.; RT "ARS-UCD1.2."; RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|Ensembl:ENSBTAP00000046113.3} RP IDENTIFICATION. RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000046113.3}; RG Ensembl; RL Submitted (FEB-2024) to UniProtKB. CC -!- SIMILARITY: Belongs to the histone H2B family. CC {ECO:0000256|ARBA:ARBA00006846}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR RefSeq; XP_010810615.1; XM_010812313.2. DR RefSeq; XP_010821041.1; XM_010822739.2. DR AlphaFoldDB; E1BM22; -. DR SMR; E1BM22; -. DR STRING; 9913.ENSBTAP00000046113; -. DR PaxDb; 9913-ENSBTAP00000046113; -. DR Ensembl; ENSBTAT00000049181.4; ENSBTAP00000046113.3; ENSBTAG00000054100.1. DR GeneID; 100300167; -. DR KEGG; bta:100300167; -. DR VEuPathDB; HostDB:ENSBTAG00000054100; -. DR eggNOG; KOG1744; Eukaryota. DR GeneTree; ENSGT01110000267246; -. DR HOGENOM; CLU_075666_2_1_1; -. DR InParanoid; E1BM22; -. DR OrthoDB; 4993770at2759; -. DR TreeFam; TF300212; -. DR Proteomes; UP000009136; Chromosome 15. DR Bgee; ENSBTAG00000054100; Expressed in gall bladder and 8 other cell types or tissues. DR GO; GO:0000786; C:nucleosome; IEA:InterPro. DR GO; GO:0003677; F:DNA binding; IEA:InterPro. DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro. DR GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro. DR Gene3D; 1.10.20.10; Histone, subunit A; 1. DR InterPro; IPR009072; Histone-fold. DR InterPro; IPR007125; Histone_H2A/H2B/H3. DR InterPro; IPR000558; Histone_H2B. DR PANTHER; PTHR23428; HISTONE H2B; 1. DR PANTHER; PTHR23428:SF190; HISTONE H2B TYPE 1-L; 1. DR Pfam; PF00125; Histone; 1. DR PRINTS; PR00621; HISTONEH2B. DR SMART; SM00427; H2B; 1. DR SUPFAM; SSF47113; Histone-fold; 1. PE 3: Inferred from homology; KW Reference proteome {ECO:0000313|Proteomes:UP000009136}. FT DOMAIN 9..101 FT /note="Histone H2A/H2B/H3" FT /evidence="ECO:0000259|Pfam:PF00125" FT REGION 1..35 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 17..31 FT /note="Basic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 126 AA; 13953 MW; BCBE6661FD781FC3 CRC64; MPELAKSSPA PKKGSKKSVT KAQKKDGKKC KHSRKESYSV YVYKVLKQVH PDTNISSKAI GIMNSFINDI FEHITGEALR LAHYNKRSTI TSREIQTAVR LLLPGELVKH TVSKGTKAVT KSTSSK //