ID E1BM22_BOVIN Unreviewed; 126 AA. AC E1BM22; DT 02-NOV-2010, integrated into UniProtKB/TrEMBL. DT 16-NOV-2011, sequence version 2. DT 05-DEC-2018, entry version 60. DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSBTAP00000046113}; OS Bos taurus (Bovine). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; OC Pecora; Bovidae; Bovinae; Bos. OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000046113, ECO:0000313|Proteomes:UP000009136}; RN [1] {ECO:0000313|Ensembl:ENSBTAP00000046113, ECO:0000313|Proteomes:UP000009136} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000046113, RC ECO:0000313|Proteomes:UP000009136}; RX PubMed=19393038; DOI=10.1186/gb-2009-10-4-r42; RA Zimin A.V., Delcher A.L., Florea L., Kelley D.R., Schatz M.C., RA Puiu D., Hanrahan F., Pertea G., Van Tassell C.P., Sonstegard T.S., RA Marcais G., Roberts M., Subramanian P., Yorke J.A., Salzberg S.L.; RT "A whole-genome assembly of the domestic cow, Bos taurus."; RL Genome Biol. 10:R42.01-R42.10(2009). RN [2] {ECO:0000313|Ensembl:ENSBTAP00000046113} RP IDENTIFICATION. RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000046113}; RG Ensembl; RL Submitted (MAR-2016) to UniProtKB. CC -!- SUBUNIT: The nucleosome is a histone octamer containing two CC molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 CC heterotetramer and two H2A-H2B heterodimers. CC {ECO:0000256|SAAS:SAAS00566009}. CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|SAAS:SAAS00680978}. CC Nucleus {ECO:0000256|SAAS:SAAS00593244}. CC -!- SIMILARITY: Belongs to the histone H2B family. CC {ECO:0000256|SAAS:SAAS00689654}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; DAAA02040087; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR RefSeq; XP_010810615.1; XM_010812313.2. DR RefSeq; XP_010821041.1; XM_010822739.2. DR SMR; E1BM22; -. DR STRING; 9913.ENSBTAP00000046113; -. DR PaxDb; E1BM22; -. DR Ensembl; ENSBTAT00000049181; ENSBTAP00000046113; ENSBTAG00000034724. DR GeneID; 100300167; -. DR KEGG; bta:100300167; -. DR eggNOG; KOG1744; Eukaryota. DR eggNOG; ENOG4111NV5; LUCA. DR GeneTree; ENSGT00940000153051; -. DR InParanoid; E1BM22; -. DR KO; K11252; -. DR OrthoDB; EOG091G0XGD; -. DR TreeFam; TF300212; -. DR Proteomes; UP000009136; Chromosome 15. DR GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0003677; F:DNA binding; IBA:GO_Central. DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro. DR GO; GO:0006334; P:nucleosome assembly; IBA:GO_Central. DR Gene3D; 1.10.20.10; -; 1. DR InterPro; IPR009072; Histone-fold. DR InterPro; IPR007125; Histone_H2A/H2B/H3. DR InterPro; IPR000558; Histone_H2B. DR PANTHER; PTHR23428; PTHR23428; 1. DR Pfam; PF00125; Histone; 1. DR PRINTS; PR00621; HISTONEH2B. DR SMART; SM00427; H2B; 1. DR SUPFAM; SSF47113; SSF47113; 1. PE 3: Inferred from homology; KW Chromosome {ECO:0000256|SAAS:SAAS00454759}; KW Complete proteome {ECO:0000313|Proteomes:UP000009136}; KW DNA-binding {ECO:0000256|SAAS:SAAS00486865}; KW Nucleosome core {ECO:0000256|SAAS:SAAS00486863}; KW Nucleus {ECO:0000256|SAAS:SAAS00486878}; KW Reference proteome {ECO:0000313|Proteomes:UP000009136}. FT DOMAIN 7 101 Histone. {ECO:0000259|Pfam:PF00125}. SQ SEQUENCE 126 AA; 13953 MW; BCBE6661FD781FC3 CRC64; MPELAKSSPA PKKGSKKSVT KAQKKDGKKC KHSRKESYSV YVYKVLKQVH PDTNISSKAI GIMNSFINDI FEHITGEALR LAHYNKRSTI TSREIQTAVR LLLPGELVKH TVSKGTKAVT KSTSSK //