ID E1BM22_BOVIN Unreviewed; 126 AA. AC E1BM22; DT 02-NOV-2010, integrated into UniProtKB/TrEMBL. DT 16-NOV-2011, sequence version 2. DT 30-AUG-2017, entry version 50. DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSBTAP00000046113}; GN Name=LOC100300167 {ECO:0000313|Ensembl:ENSBTAP00000046113}; OS Bos taurus (Bovine). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; OC Pecora; Bovidae; Bovinae; Bos. OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000046113, ECO:0000313|Proteomes:UP000009136}; RN [1] {ECO:0000313|Ensembl:ENSBTAP00000046113, ECO:0000313|Proteomes:UP000009136} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000046113, RC ECO:0000313|Proteomes:UP000009136}; RX PubMed=19393038; DOI=10.1186/gb-2009-10-4-r42; RA Zimin A.V., Delcher A.L., Florea L., Kelley D.R., Schatz M.C., RA Puiu D., Hanrahan F., Pertea G., Van Tassell C.P., Sonstegard T.S., RA Marcais G., Roberts M., Subramanian P., Yorke J.A., Salzberg S.L.; RT "A whole-genome assembly of the domestic cow, Bos taurus."; RL Genome Biol. 10:R42.01-R42.10(2009). RN [2] {ECO:0000313|Ensembl:ENSBTAP00000046113} RP IDENTIFICATION. RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000046113}; RG Ensembl; RL Submitted (MAR-2016) to UniProtKB. CC -!- SUBUNIT: The nucleosome is a histone octamer containing two CC molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 CC heterotetramer and two H2A-H2B heterodimers. CC {ECO:0000256|SAAS:SAAS00566009}. CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|SAAS:SAAS00680978}. CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|SAAS:SAAS00593244}. CC -!- SIMILARITY: Belongs to the histone H2B family. CC {ECO:0000256|SAAS:SAAS00689654}. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. {ECO:0000313|Ensembl:ENSBTAP00000046113}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; DAAA02040087; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR RefSeq; XP_010810615.1; XM_010812313.2. DR RefSeq; XP_010821041.1; XM_010822739.2. DR STRING; 9913.ENSBTAP00000046113; -. DR PaxDb; E1BM22; -. DR Ensembl; ENSBTAT00000049181; ENSBTAP00000046113; ENSBTAG00000034724. DR GeneID; 100300167; -. DR KEGG; bta:100300167; -. DR eggNOG; KOG1744; Eukaryota. DR eggNOG; ENOG4111NV5; LUCA. DR GeneTree; ENSGT00890000139368; -. DR InParanoid; E1BM22; -. DR KO; K11252; -. DR OrthoDB; EOG091G0XGD; -. DR TreeFam; TF300212; -. DR Reactome; R-BTA-3214847; HATs acetylate histones. DR Reactome; R-BTA-8866654; E3 ubiquitin ligases ubiquitinate target proteins. DR Proteomes; UP000009136; Chromosome 15. DR GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0003677; F:DNA binding; IBA:GO_Central. DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro. DR GO; GO:0006334; P:nucleosome assembly; IBA:GO_Central. DR InterPro; IPR009072; Histone-fold. DR InterPro; IPR007125; Histone_H2A/H2B/H3. DR InterPro; IPR000558; Histone_H2B. DR PANTHER; PTHR23428; PTHR23428; 1. DR Pfam; PF00125; Histone; 1. DR PRINTS; PR00621; HISTONEH2B. DR SMART; SM00427; H2B; 1. DR SUPFAM; SSF47113; SSF47113; 1. PE 3: Inferred from homology; KW Chromosome {ECO:0000256|SAAS:SAAS00454759}; KW Complete proteome {ECO:0000313|Proteomes:UP000009136}; KW DNA-binding {ECO:0000256|SAAS:SAAS00486865}; KW Nucleosome core {ECO:0000256|SAAS:SAAS00454795}; KW Nucleus {ECO:0000256|SAAS:SAAS00486878}; KW Reference proteome {ECO:0000313|Proteomes:UP000009136}. FT DOMAIN 7 101 Histone. {ECO:0000259|Pfam:PF00125}. SQ SEQUENCE 126 AA; 13953 MW; BCBE6661FD781FC3 CRC64; MPELAKSSPA PKKGSKKSVT KAQKKDGKKC KHSRKESYSV YVYKVLKQVH PDTNISSKAI GIMNSFINDI FEHITGEALR LAHYNKRSTI TSREIQTAVR LLLPGELVKH TVSKGTKAVT KSTSSK //