ID   E1BM22_BOVIN            Unreviewed;       126 AA.
AC   E1BM22;
DT   02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 2.
DT   05-SEP-2012, entry version 13.
DE   SubName: Full=Uncharacterized protein;
GN   Name=LOC100300167;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
OC   Pecora; Bovidae; Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hereford;
RX   PubMed=19393038; DOI=10.1186/gb-2009-10-4-r42;
RA   Zimin A.V., Delcher A.L., Florea L., Kelley D.R., Schatz M.C.,
RA   Puiu D., Hanrahan F., Pertea G., Van Tassell C.P., Sonstegard T.S.,
RA   Marcais G., Roberts M., Subramanian P., Yorke J.A., Salzberg S.L.;
RT   "A whole-genome assembly of the domestic cow, Bos taurus.";
RL   Genome Biol. 10:R42-R42(2009).
RN   [2]
RP   IDENTIFICATION.
RC   STRAIN=Hereford;
RG   Ensembl;
RL   Submitted (MAY-2011) to UniProtKB.
CC   -!- FUNCTION: Core component of nucleosome. Nucleosomes wrap and
CC       compact DNA into chromatin, limiting DNA accessibility to the
CC       cellular machineries which require DNA as a template. Histones
CC       thereby play a central role in transcription regulation, DNA
CC       repair, DNA replication and chromosomal stability. DNA
CC       accessibility is regulated via a complex set of post-translational
CC       modifications of histones, also called histone code, and
CC       nucleosome remodeling (By similarity).
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data.
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DR   EMBL; DAAA02040087; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   IPI; IPI00705006; -.
DR   RefSeq; XP_002692992.1; XM_002692946.1.
DR   RefSeq; XP_002701340.1; XM_002701294.1.
DR   PRIDE; E1BM22; -.
DR   Ensembl; ENSBTAT00000049181; ENSBTAP00000046113; ENSBTAG00000034724.
DR   GeneID; 100300167; -.
DR   KEGG; bta:100300167; -.
DR   GeneTree; ENSGT00670000098726; -.
DR   GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR   Gene3D; G3DSA:1.10.20.10; Histone-fold; 1.
DR   InterPro; IPR009072; Histone-fold.
DR   InterPro; IPR007125; Histone_core_D.
DR   InterPro; IPR000558; Histone_H2B.
DR   PANTHER; PTHR23428; Histone_H2B; 1.
DR   Pfam; PF00125; Histone; 1.
DR   PRINTS; PR00621; HISTONEH2B.
DR   SMART; SM00427; H2B; 1.
DR   SUPFAM; SSF47113; Histone-fold; 1.
PE   3: Inferred from homology;
KW   Chromosome; Complete proteome; DNA-binding; Isopeptide bond;
KW   Nucleosome core; Nucleus; Reference proteome.
SQ   SEQUENCE   126 AA;  13953 MW;  BCBE6661FD781FC3 CRC64;
     MPELAKSSPA PKKGSKKSVT KAQKKDGKKC KHSRKESYSV YVYKVLKQVH PDTNISSKAI
     GIMNSFINDI FEHITGEALR LAHYNKRSTI TSREIQTAVR LLLPGELVKH TVSKGTKAVT
     KSTSSK
//