ID E1BDK7_BOVIN Unreviewed; 777 AA. AC E1BDK7; DT 02-NOV-2010, integrated into UniProtKB/TrEMBL. DT 16-NOV-2011, sequence version 2. DT 26-FEB-2020, entry version 59. DE SubName: Full=ElaC ribonuclease Z 2 {ECO:0000313|Ensembl:ENSBTAP00000029249}; GN Name=ELAC2 {ECO:0000313|Ensembl:ENSBTAP00000029249, GN ECO:0000313|VGNC:VGNC:28422}; OS Bos taurus (Bovine). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; OC Bovinae; Bos. OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000029249, ECO:0000313|Proteomes:UP000009136}; RN [1] {ECO:0000313|Ensembl:ENSBTAP00000029249} RP IDENTIFICATION. RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000029249}; RG Ensembl; RL Submitted (MAR-2016) to UniProtKB. RN [2] {ECO:0000313|Ensembl:ENSBTAP00000029249, ECO:0000313|Proteomes:UP000009136} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000029249, RC ECO:0000313|Proteomes:UP000009136}; RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A., RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C., RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.; RT "ARS-UCD1.2."; RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR RefSeq; NP_001179994.1; NM_001193065.1. DR SMR; E1BDK7; -. DR STRING; 9913.ENSBTAP00000029249; -. DR PaxDb; E1BDK7; -. DR Ensembl; ENSBTAT00000029249; ENSBTAP00000029249; ENSBTAG00000021939. DR GeneID; 509256; -. DR KEGG; bta:509256; -. DR CTD; 60528; -. DR VGNC; VGNC:28422; ELAC2. DR eggNOG; KOG2121; Eukaryota. DR eggNOG; COG1234; LUCA. DR GeneTree; ENSGT00730000111191; -. DR HOGENOM; CLU_006220_2_0_1; -. DR InParanoid; E1BDK7; -. DR KO; K00784; -. DR OMA; CFEDSIL; -. DR OrthoDB; 454909at2759; -. DR TreeFam; TF105797; -. DR Proteomes; UP000009136; Chromosome 19. DR Bgee; ENSBTAG00000021939; Expressed in heart and 8 other tissues. DR GO; GO:0042645; C:mitochondrial nucleoid; IEA:Ensembl. DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central. DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl. DR GO; GO:0072684; P:mitochondrial tRNA 3'-trailer cleavage, endonucleolytic; IBA:GO_Central. DR Gene3D; 3.60.15.10; -; 2. DR InterPro; IPR001279; Metallo-B-lactamas. DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro. DR InterPro; IPR027794; tRNase_Z_dom. DR Pfam; PF12706; Lactamase_B_2; 1. DR Pfam; PF13691; Lactamase_B_4; 1. DR SUPFAM; SSF56281; SSF56281; 2. PE 4: Predicted; KW Reference proteome {ECO:0000313|Proteomes:UP000009136}; KW Signal {ECO:0000256|SAM:SignalP}. FT SIGNAL 1..19 FT /evidence="ECO:0000256|SAM:SignalP" FT CHAIN 20..777 FT /evidence="ECO:0000256|SAM:SignalP" FT /id="PRO_5003143966" FT DOMAIN 57..116 FT /note="Lactamase_B_4" FT /evidence="ECO:0000259|Pfam:PF13691" FT DOMAIN 466..679 FT /note="Lactamase_B" FT /evidence="ECO:0000259|Pfam:PF12706" FT REGION 17..49 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 748..777 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 27..42 FT /note="Polyampholyte" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 777 AA; 86003 MW; 7026F87BCB1BF40D CRC64; MWALRSLLGL RCAAGRTMSQ GPARRPRPPK DPLRHLRTRE KRGPSWGPGG PNTVYLQVVA AGGRDAGAAL YVFSEFNRYL FNCGEGVQRL MQEHKLKVSR LDNIFLTRMH WSNVGGLCGM ILTLKETGVP KCVLSGPPQL EKYLEAIKIF SGPLKGIDLA VRPHSAPEYK DETMTVFQIP IHCVGWKARG RDTSLVVAFV CKLHVKKGNF LVLKAKELGL PVGTAAIAPI IAAVKDGKSV TYEGREILPE EICTPPDPGI TFIVVECPDE GFIQPLCENT TFRSYQGKAD APVALVVHMA PEHVLLDSRY QQWMERFGPD TEHLVLNETC ESVHNLRSHK IQTQLSLIHP GIFPPLAGPR PQEGSATQGV PTVRGQCLLK YQLRPRREWQ RDAVLTCDPE EFIAEALELP NFQESVQEYR KTAQDSPEAT SSQYPEVVFL GTGSAIPMKI RNVSSTLVNI SPDTSLLLDC GEGTFGQLCR HYGDGVDRVL GSLAAVFVSH LHADHHTGLL NILLQRERAL ASLGRPCHPL LVVAPTQLRT WLQQYHNQCQ PLLHHVSVIP AKCLQKGAEV SSPEVERLIN LLLETCGLEE FQTCLVRHCK HAFGCALVHM SGWKVVYSGD TMPCEALVQM GKDATLLIHE ATLEDGLEEE AVEKTHSTTS QAIGVGMRMS AAFIMLTHFS QRYAKIPLFS PDFNEKVGIA FDHMKVSLGD LPTVPRLTAP LKALFAGDLE EMEGRRERRE LRQVRAALLA GEDVEPPQKR APTEHPLSPQ SKKARAQ //