ID E0CXK7_MOUSE Unreviewed; 296 AA. AC E0CXK7; DT 05-OCT-2010, integrated into UniProtKB/TrEMBL. DT 09-DEC-2015, sequence version 2. DT 07-OCT-2020, entry version 70. DE SubName: Full=Homeobox protein Hox-A13 {ECO:0000313|Ensembl:ENSMUSP00000125221}; GN Name=Hoxa13 {ECO:0000313|Ensembl:ENSMUSP00000125221, GN ECO:0000313|MGI:MGI:96173}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000125221, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000125221, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000125221, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., RA Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of the RT mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000313|Ensembl:ENSMUSP00000125221} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000125221}; RG Ensembl; RL Submitted (MAY-2011) to UniProtKB. CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123, CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}. CC -!- SIMILARITY: Belongs to the Abd-B homeobox family. CC {ECO:0000256|ARBA:ARBA00006317}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC015583; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; FQ828346; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR SMR; E0CXK7; -. DR Antibodypedia; 12410; 144 antibodies. DR Ensembl; ENSMUST00000147595; ENSMUSP00000125221; ENSMUSG00000038203. DR MGI; MGI:96173; Hoxa13. DR GeneTree; ENSGT00940000162322; -. DR HOGENOM; CLU_059940_2_1_1; -. DR Proteomes; UP000000589; Chromosome 6. DR Bgee; ENSMUSG00000038203; Expressed in undifferentiated genital tubercle and 117 other tissues. DR ExpressionAtlas; E0CXK7; baseline and differential. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule. DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro. DR CDD; cd00086; homeodomain; 1. DR InterPro; IPR009057; Homeobox-like_sf. DR InterPro; IPR017970; Homeobox_CS. DR InterPro; IPR001356; Homeobox_dom. DR InterPro; IPR022067; HoxA13_N. DR Pfam; PF00046; Homeodomain; 1. DR Pfam; PF12284; HoxA13_N; 1. DR SMART; SM00389; HOX; 1. DR SUPFAM; SSF46689; SSF46689; 1. DR PROSITE; PS00027; HOMEOBOX_1; 1. DR PROSITE; PS50071; HOMEOBOX_2; 1. PE 3: Inferred from homology; KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE- KW ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}; KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE- KW ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}; KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE- KW ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}. FT DOMAIN 228..288 FT /note="Homeobox" FT /evidence="ECO:0000259|PROSITE:PS50071" FT DNA_BIND 230..289 FT /note="Homeobox" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108" SQ SEQUENCE 296 AA; 31136 MW; 0F4E5FF4140D85B7 CRC64; MAHPAPLAPG AAAAYSSAPG EAPPSAAAAA AAAAAAAAAA AAASSSGGPG PAGPAGAEAA KQCSPCSAAA QSSSGPAALP YGYFGSGYYP CARMGPHPNA IKSCAQPASA AAAFADKYMD TAGPAAEEFS SRAKEFAFYH QGYAAGPYHH HQPVPGYLDM PVVPGLGGPG ESRHEPLGLP MESYQPWALP NGWNGQMYCP KEQTQPPHLW KSTLPDVVSH PSDASSYRRG RKKRVPYTKV QLKELEREYA TNKFITKDKR RRISATTNLS ERQVTIWFQN RRVKEKKVIN KLKTTS //