ID E0CXK7_MOUSE Unreviewed; 296 AA. AC E0CXK7; DT 05-OCT-2010, integrated into UniProtKB/TrEMBL. DT 09-DEC-2015, sequence version 2. DT 09-DEC-2015, entry version 43. DE SubName: Full=Homeobox protein Hox-A13 {ECO:0000313|Ensembl:ENSMUSP00000125221}; GN Name=Hoxa13 {ECO:0000313|Ensembl:ENSMUSP00000125221, GN ECO:0000313|MGI:MGI:96173}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000125221, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000125221, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000125221, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., RA Lindblad-Toh K., Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of RT the mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000313|Ensembl:ENSMUSP00000125221} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000125221}; RG Ensembl; RL Submitted (MAY-2011) to UniProtKB. CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU000682}. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. {ECO:0000313|Ensembl:ENSMUSP00000125221}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC015583; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; FQ828346; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR ProteinModelPortal; E0CXK7; -. DR SMR; E0CXK7; 137-203. DR STRING; 10090.ENSMUSP00000039170; -. DR PaxDb; E0CXK7; -. DR Ensembl; ENSMUST00000147595; ENSMUSP00000125221; ENSMUSG00000038203. DR MGI; MGI:96173; Hoxa13. DR eggNOG; ENOG4111FJP; LUCA. DR eggNOG; KOG0487; Eukaryota. DR OrthoDB; EOG7SJD53; -. DR NextBio; 35553012; -. DR Proteomes; UP000000589; Chromosome 6. DR Bgee; E0CXK7; -. DR ExpressionAtlas; E0CXK7; baseline and differential. DR GO; GO:0045111; C:intermediate filament cytoskeleton; ISO:MGI. DR GO; GO:0005654; C:nucleoplasm; ISO:MGI. DR GO; GO:0005634; C:nucleus; IDA:MGI. DR GO; GO:0003677; F:DNA binding; IDA:MGI. DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro. DR GO; GO:0003700; F:transcription factor activity, sequence-specific DNA binding; IDA:MGI. DR GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:MGI. DR GO; GO:0009653; P:anatomical structure morphogenesis; IMP:MGI. DR GO; GO:0048844; P:artery morphogenesis; IMP:MGI. DR GO; GO:0060442; P:branching involved in prostate gland morphogenesis; IMP:MGI. DR GO; GO:0035115; P:embryonic forelimb morphogenesis; IMP:MGI. DR GO; GO:0060847; P:endothelial cell fate specification; IMP:MGI. DR GO; GO:0001886; P:endothelial cell morphogenesis; IMP:MGI. DR GO; GO:0048839; P:inner ear development; IMP:MGI. DR GO; GO:0030539; P:male genitalia development; IMP:MGI. DR GO; GO:0009887; P:organ morphogenesis; IMP:MGI. DR GO; GO:2001055; P:positive regulation of mesenchymal cell apoptotic process; IMP:MGI. DR GO; GO:0045840; P:positive regulation of mitotic nuclear division; IMP:MGI. DR GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI. DR GO; GO:0030510; P:regulation of BMP signaling pathway; IMP:MGI. DR GO; GO:0001894; P:tissue homeostasis; IMP:MGI. DR GO; GO:0001570; P:vasculogenesis; IMP:MGI. DR GO; GO:0003281; P:ventricular septum development; IMP:MGI. DR Gene3D; 1.10.10.60; -; 1. DR InterPro; IPR017970; Homeobox_CS. DR InterPro; IPR001356; Homeobox_dom. DR InterPro; IPR009057; Homeodomain-like. DR InterPro; IPR022067; HoxA13_N. DR Pfam; PF00046; Homeobox; 1. DR Pfam; PF12284; HoxA13_N; 1. DR SMART; SM00389; HOX; 1. DR SUPFAM; SSF46689; SSF46689; 1. DR PROSITE; PS00027; HOMEOBOX_1; 1. DR PROSITE; PS50071; HOMEOBOX_2; 1. PE 4: Predicted; KW Complete proteome {ECO:0000313|Proteomes:UP000000589}; KW DNA-binding {ECO:0000256|RuleBase:RU000682}; KW Homeobox {ECO:0000256|RuleBase:RU000682}; KW Nucleus {ECO:0000256|RuleBase:RU000682}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}. FT DOMAIN 135 195 Homeobox DNA-binding. FT {ECO:0000259|PROSITE:PS50071}. SQ SEQUENCE 296 AA; 31136 MW; 0F4E5FF4140D85B7 CRC64; MAHPAPLAPG AAAAYSSAPG EAPPSAAAAA AAAAAAAAAA AAASSSGGPG PAGPAGAEAA KQCSPCSAAA QSSSGPAALP YGYFGSGYYP CARMGPHPNA IKSCAQPASA AAAFADKYMD TAGPAAEEFS SRAKEFAFYH QGYAAGPYHH HQPVPGYLDM PVVPGLGGPG ESRHEPLGLP MESYQPWALP NGWNGQMYCP KEQTQPPHLW KSTLPDVVSH PSDASSYRRG RKKRVPYTKV QLKELEREYA TNKFITKDKR RRISATTNLS ERQVTIWFQN RRVKEKKVIN KLKTTS //