ID   D9IWY2_ARATH            Unreviewed;       583 AA.
AC   D9IWY2;
DT   05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2010, sequence version 1.
DT   12-OCT-2022, entry version 45.
DE   SubName: Full=Accelerated cell death 6 {ECO:0000313|EMBL:ADJ38615.1};
DE   Flags: Fragment;
GN   OrderedLocusNames=At4g14400 {ECO:0000313|EMBL:ADJ38615.1};
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702 {ECO:0000313|EMBL:ADJ38615.1};
RN   [1] {ECO:0000313|EMBL:ADJ38615.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=20520716; DOI=10.1038/nature09083;
RA   Todesco M., Balasubramanian S., Hu T.T., Traw M.B., Horton M., Epple P.,
RA   Kuhns C., Sureshkumar S., Schwartz C., Lanz C., Laitinen R.A.E., Huang Y.,
RA   Chory J., Lipka V., Borevitz J.O., Dangl J.L., Bergelson J., Nordborg M.,
RA   Weigel D.;
RT   "Natural allelic variation underlying a major fitness trade-off in
RT   Arabidopsis thaliana.";
RL   Nature 465:632-636(2010).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; HM214844; ADJ38615.1; -; Genomic_DNA.
DR   EMBL; HM214845; ADJ38616.1; -; Genomic_DNA.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0071446; P:cellular response to salicylic acid stimulus; IEA:InterPro.
DR   GO; GO:0031347; P:regulation of defense response; IEA:InterPro.
DR   GO; GO:2000031; P:regulation of salicylic acid mediated signaling pathway; IEA:InterPro.
DR   Gene3D; 1.25.40.20; -; 2.
DR   InterPro; IPR032846; ACD6.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR026961; PGG_dom.
DR   PANTHER; PTHR24177:SF322; PTHR24177:SF322; 1.
DR   Pfam; PF12796; Ank_2; 2.
DR   Pfam; PF13962; PGG; 1.
DR   SMART; SM00248; ANK; 9.
DR   SUPFAM; SSF48403; SSF48403; 1.
DR   PROSITE; PS50088; ANK_REPEAT; 1.
PE   4: Predicted;
KW   ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW   ProRule:PRU00023};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        493..516
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        536..560
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REPEAT          134..155
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   DOMAIN          487..582
FT                   /note="PGG"
FT                   /evidence="ECO:0000259|Pfam:PF13962"
FT   REGION          20..46
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        30..44
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         583
FT                   /evidence="ECO:0000313|EMBL:ADJ38615.1"
SQ   SEQUENCE   583 AA;  64108 MW;  0047D3309F692CE6 CRC64;
     MDSSEADLDR IEAQRSMXXX XXXXXXFSHS GGVGTTSPTG DTEPVPKFRT NLKLSDLFAL
     PGEDVEMTPE IFGGMSNGEK ECLEKLRSNG TPMERVKSNT GDSILHIAAK WGHLELVKEI
     VFECPCLLFE QNSSRQTPLH VAAHGGHTKV VEALVASVTS ASASLSTEKS ERLNPHVLKD
     EDGNTALYYA IEGRYLEMAT CLVNADKDAP FLGNNKGISS LYEAVDAGNK FEDLVKAILK
     TTDDNVDREV RKFNLDSKLQ GNKHLAHFAL KAKSIGVLDV ILDEYPSLMD EQDEDGRTCL
     SYGASIGYYK GVCNILNRST KGVYVCDQDG SFPIHTAAEK GHKNIVEEFI KRCPGSKHLL
     NKLGQNVLHI AAKNGKFWIS NMLIINKDTE HLGVGQDVDG NTPLHLAVMN WDFYSITCLA
     SRNCEILKLR NKSGLRARDI AESEVKPNYI FHERWTLALL LYAIHSSGFE SVKSLTIQSE
     PLDPKNNRHY VNALLVVAAL VATVTFAAGF TIPGGYISDS KKPNLGRATL ATNPTLFIFL
     LFDILAMQSS VATICTLIWA QLGDPKLIRR SLHVALPLLL FSL
//