ID D6RAK8_HUMAN Unreviewed; 493 AA. AC D6RAK8; DT 13-JUL-2010, integrated into UniProtKB/TrEMBL. DT 13-JUL-2010, sequence version 1. DT 03-OCT-2012, entry version 18. DE SubName: Full=Vitamin D-binding protein; GN Name=GC; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=15815621; DOI=10.1038/nature03466; RA Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., RA Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., RA Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., RA Kremitzki C., Oddy L., Du H., Sun H., Bradshaw-Cordum H., Ali J., RA Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., RA Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., RA Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., RA Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., RA Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., RA Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., RA McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., RA Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., RA Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., RA Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., RA Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., RA Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., RA Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., RA Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., RA Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., RA Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., RA McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., RA Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., RA Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., RA Waterston R.H., Wilson R.K.; RT "Generation and annotation of the DNA sequences of human chromosomes 2 RT and 4."; RL Nature 434:724-731(2005). RN [2] RP IDENTIFICATION. RG Ensembl; RL Submitted (JUL-2011) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC024722; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR IPI; IPI00968027; -. DR RefSeq; NP_001191236.1; NM_001204307.1. DR UniGene; Hs.418497; -. DR ProteinModelPortal; D6RAK8; -. DR SMR; D6RAK8; 39-493. DR PRIDE; D6RAK8; -. DR Ensembl; ENST00000504199; ENSP00000421725; ENSG00000145321. DR GeneID; 2638; -. DR KEGG; hsa:2638; -. DR UCSC; uc003hge.3; human. DR CTD; 2638; -. DR HGNC; HGNC:4187; GC. DR GeneTree; ENSGT00390000000113; -. DR HOGENOM; HOG000140946; -. DR KO; K12258; -. DR OMA; EDCMAKE; -. DR GenomeRNAi; 2638; -. DR NextBio; 10400; -. DR Bgee; D6RAK8; -. DR GO; GO:0005615; C:extracellular space; IEA:InterPro. DR GO; GO:0005499; F:vitamin D binding; IEA:InterPro. DR GO; GO:0051183; F:vitamin transporter activity; IEA:InterPro. DR InterPro; IPR000264; Serum_albumin. DR InterPro; IPR020858; Serum_albumin-like. DR InterPro; IPR020857; Serum_albumin_CS. DR InterPro; IPR014760; Serum_albumin_N. DR InterPro; IPR000213; VitD-bd. DR InterPro; IPR015247; VitD-bind_III. DR Pfam; PF00273; Serum_albumin; 2. DR Pfam; PF09164; VitD-bind_III; 1. DR PRINTS; PR00802; SERUMALBUMIN. DR PRINTS; PR00804; VITAMNDBNDNG. DR SMART; SM00103; ALBUMIN; 2. DR SUPFAM; SSF48552; Serum_albumin; 3. DR PROSITE; PS00212; ALBUMIN_1; 1. DR PROSITE; PS51438; ALBUMIN_2; 2. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 493 AA; 55077 MW; E6E08F41F3ACD511 CRC64; MLWSWSEERG GAARLSGRKM KRVLVLLLAV AFGHALERGR DYEKNKVCKE FSHLGKEDFT SLSLVLYSRK FPSGTFEQVS QLVKEVVSLT EACCAEGADP DCYDTRTSAL SAKSCESNSP FPVHPGTAEC CTKEGLERKL CMAALKHQPQ EFPTYVEPTN DEICEAFRKD PKEYANQFMW EYSTNYGQAP LSLLVSYTKS YLSMVGSCCT SASPTVCFLK ERLQLKHLSL LTTLSNRVCS QYAAYGEKKS RLSNLIKLAQ KVPTADLEDV LPLAEDITNI LSKCCESASE DCMAKELPEH TVKLCDNLST KNSKFEDCCQ EKTAMDVFVC TYFMPAAQLP ELPDVELPTN KDVCDPGNTK VMDKYTFELS RRTHLPEVFL SKVLEPTLKS LGECCDVEDS TTCFNAKGPL LKKELSSFID KGQELCADYS ENTFTEYKKK LAERLKAKLP DATPTELAKL VNKHSDFASN CCSINSPPLY CDSEIDAELK NIL //