ID D6C4G1_BOVIN Unreviewed; 359 AA. AC D6C4G1; DT 13-JUL-2010, integrated into UniProtKB/TrEMBL. DT 13-JUL-2010, sequence version 1. DT 25-OCT-2017, entry version 43. DE SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADB93147.1}; GN Name=BoLA {ECO:0000313|EMBL:ADB93147.1}; OS Bos taurus (Bovine). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; OC Pecora; Bovidae; Bovinae; Bos. OX NCBI_TaxID=9913 {ECO:0000313|EMBL:ADB93147.1}; RN [1] {ECO:0000313|EMBL:ADB93147.1} RP NUCLEOTIDE SEQUENCE. RA Li X.Y., Jiang Y.N., Xia C.; RT "Bos taurus BoLA antigen."; RL Submitted (APR-2009) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|EMBL:AFS51773.1} RP NUCLEOTIDE SEQUENCE. RC TISSUE=Kidney {ECO:0000313|EMBL:AFS51773.1}; RA Li X., Jiang Y., Li X., Xia C.; RT "New Bovine MHC Class I Sequences."; RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases. CC -!- SUBUNIT: Heterodimer of an alpha chain and a beta chain (beta-2- CC microglobulin). {ECO:0000256|SAAS:SAAS00870536}. CC -!- SIMILARITY: Belongs to the MHC class I family. CC {ECO:0000256|RuleBase:RU004439, ECO:0000256|SAAS:SAAS00560993}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; FJ952945; ADB93147.1; -; mRNA. DR EMBL; JQ031609; AFS51773.1; -; mRNA. DR RefSeq; NP_001180225.1; NM_001193296.1. DR UniGene; Bt.88540; -. DR SMR; D6C4G1; -. DR GeneID; 505676; -. DR KEGG; bta:505676; -. DR CTD; 505676; -. DR KO; K06751; -. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0042612; C:MHC class I protein complex; IEA:UniProtKB-KW. DR GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; IEA:UniProtKB-KW. DR GO; GO:0006955; P:immune response; IEA:InterPro. DR Gene3D; 2.60.40.10; -; 1. DR Gene3D; 3.30.500.10; -; 1. DR InterPro; IPR007110; Ig-like_dom. DR InterPro; IPR036179; Ig-like_dom_sf. DR InterPro; IPR013783; Ig-like_fold. DR InterPro; IPR003006; Ig/MHC_CS. DR InterPro; IPR003597; Ig_C1-set. DR InterPro; IPR011161; MHC_I-like_Ag-recog. DR InterPro; IPR037055; MHC_I-like_Ag-recog_sf. DR InterPro; IPR011162; MHC_I/II-like_Ag-recog. DR InterPro; IPR001039; MHC_I_a_a1/a2. DR InterPro; IPR010579; MHC_I_a_C. DR Pfam; PF07654; C1-set; 1. DR Pfam; PF00129; MHC_I; 1. DR Pfam; PF06623; MHC_I_C; 1. DR PRINTS; PR01638; MHCCLASSI. DR SMART; SM00407; IGc1; 1. DR SUPFAM; SSF48726; SSF48726; 1. DR SUPFAM; SSF54452; SSF54452; 1. DR PROSITE; PS50835; IG_LIKE; 1. DR PROSITE; PS00290; IG_MHC; 1. PE 2: Evidence at transcript level; KW Immunity {ECO:0000256|SAAS:SAAS00447805}; KW Membrane {ECO:0000256|SAAS:SAAS00446121, ECO:0000256|SAM:Phobius}; KW MHC I {ECO:0000256|SAAS:SAAS00446101}; KW Signal {ECO:0000256|SAM:SignalP}; KW Transmembrane {ECO:0000256|SAAS:SAAS00292265, KW ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAAS:SAAS00447790, KW ECO:0000256|SAM:Phobius}. FT SIGNAL 1 21 {ECO:0000256|SAM:SignalP}. FT CHAIN 22 359 {ECO:0000256|SAM:SignalP}. FT /FTId=PRO_5010112235. FT TRANSMEM 301 325 Helical. {ECO:0000256|SAM:Phobius}. FT DOMAIN 205 291 Ig-like. {ECO:0000259|PROSITE:PS50835}. SQ SEQUENCE 359 AA; 40140 MW; 6A2F4F095F2216ED CRC64; MGPRTLLLLL SGVLVLTETR AGSHSMRYFS TAVSRPGLGE PRYLEVGYVD DTQFVRFDSD APNPRIEPTA RWVEQEGPEY WHQETQRTKD TAQFFRVYLN TLRGYYNQSE AGSHTVQEMY GCDVGPDGLL RGYDQFAYDG RDYIALNEDL RSWTAADTAA QVTKHNAEAA GDAARVRIYL EGTCVEWLRR YLETGKDTLL RADPPKAHVT HHSISGHEVT LRCWALGFYP EDISLTWQRN GEDQTQDMEL VETRPSGDGN FQKWAALVVP SGEEQKYTCR VQHEGLQEPL TLKWEPPQPS FLTMGIIVGL VLLVVTGAVV AGVVICMKKR SGEKRGTYIQ ASSSDSAQGS DVSLTVPKV //