ID D5FAJ5_9INFA Unreviewed; 65 AA. AC D5FAJ5; DT 15-JUN-2010, integrated into UniProtKB/TrEMBL. DT 15-JUN-2010, sequence version 1. DT 27-NOV-2024, entry version 61. DE SubName: Full=Matrix protein 2 {ECO:0000313|EMBL:ADE48156.1}; DE Flags: Fragment; GN Name=M2 {ECO:0000313|EMBL:ADE48156.1}; OS Influenza A virus (A/Guangxi/1/2005(H5N1)). OC Viruses; Riboviria; Orthornavirae; Negarnaviricota; Polyploviricotina; OC Insthoviricetes; Articulavirales; Orthomyxoviridae; Alphainfluenzavirus; OC Alphainfluenzavirus influenzae; Influenza A virus. OX NCBI_TaxID=370812 {ECO:0000313|EMBL:ADE48156.1, ECO:0000313|Proteomes:UP000105802}; RN [1] {ECO:0000313|EMBL:ADE48156.1, ECO:0000313|Proteomes:UP000105802} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=A/Guangxi/1/2005 {ECO:0000313|EMBL:ADE48156.1}; RX PubMed=20834097; DOI=10.3851/IMP1656; RA Lan Y., Zhang Y., Dong L., Wang D., Huang W., Xin L., Yang L., Zhao X., RA Li Z., Wang W., Li X., Xu C., Yang L., Guo J., Wang M., Peng Y., Gao Y., RA Guo Y., Wen L., Jiang T., Shu Y.; RT "A comprehensive surveillance of adamantane resistance among human RT influenza A virus isolated from mainland China between 1956 and 2009."; RL Antivir. Ther. 15:853-859(2010). RN [2] {ECO:0000313|EMBL:ADE48156.1, ECO:0000313|Proteomes:UP000105802} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=A/Guangxi/1/2005 {ECO:0000313|EMBL:ADE48156.1}; RX PubMed=21976646; DOI=10.1128/JVI.05266-11; RA Wan X.F., Dong L., Lan Y., Long L.P., Xu C., Zou S., Li Z., Wen L., Cai Z., RA Wang W., Li X., Yuan F., Sui H., Zhang Y., Dong J., Sun S., Gao Y., RA Wang M., Bai T., Yang L., Li D., Yang W., Yu H., Wang S., Feng Z., Wang Y., RA Guo Y., Webby R.J., Shu Y.; RT "Indications that Live Poultry Markets Are a Major Source of Human H5N1 RT Influenza Virus Infection in China."; RL J. Virol. 85:13432-13438(2011). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CY060158; ADE48156.1; -; Viral_cRNA. DR Proteomes; UP000105802; Genome. DR GO; GO:0033644; C:host cell membrane; IEA:UniProtKB-KW. DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW. DR GO; GO:0055036; C:virion membrane; IEA:InterPro. DR GO; GO:0015267; F:channel activity; IEA:UniProtKB-KW. DR GO; GO:0015078; F:proton transmembrane transporter activity; IEA:InterPro. DR Gene3D; 6.10.250.1640; -; 1. DR InterPro; IPR002089; Flu_M2. DR Pfam; PF00599; Flu_M2; 1. PE 4: Predicted; KW Host cell membrane {ECO:0000256|ARBA:ARBA00022511}; KW Host membrane {ECO:0000256|ARBA:ARBA00022870}; KW Hydrogen ion transport {ECO:0000256|ARBA:ARBA00022781}; KW Ion channel {ECO:0000256|ARBA:ARBA00023303}; KW Ion transport {ECO:0000256|ARBA:ARBA00023065}; KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288}; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius}; KW Palmitate {ECO:0000256|ARBA:ARBA00023139}; KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}; KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968}; KW Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}; KW Transport {ECO:0000256|ARBA:ARBA00022448}; KW Viral ion channel {ECO:0000256|ARBA:ARBA00023039}; KW Virion {ECO:0000256|ARBA:ARBA00022844}. FT TRANSMEM 17..39 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:ADE48156.1" FT NON_TER 65 FT /evidence="ECO:0000313|EMBL:ADE48156.1" SQ SEQUENCE 65 AA; 7537 MW; D1C2532EE3D8D6DF CRC64; PTRNEWECRC SDSSDPLVVA ASIIGILHLI LWILDRLFFK CIYRRLKYGL KRGPSTEGVP ESMRE //