ID D3ZCY9_RAT Unreviewed; 313 AA. AC D3ZCY9; DT 20-APR-2010, integrated into UniProtKB/TrEMBL. DT 03-APR-2013, sequence version 2. DT 18-JUL-2018, entry version 76. DE RecName: Full=Olfactory receptor {ECO:0000256|RuleBase:RU363047}; GN Name=Olr1235 {ECO:0000313|Ensembl:ENSRNOP00000050333, GN ECO:0000313|RGD:1334039}; OS Rattus norvegicus (Rat). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; OC Muroidea; Muridae; Murinae; Rattus. OX NCBI_TaxID=10116 {ECO:0000313|Ensembl:ENSRNOP00000050333, ECO:0000313|Proteomes:UP000002494}; RN [1] {ECO:0000313|Ensembl:ENSRNOP00000050333, ECO:0000313|Proteomes:UP000002494} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000050333, RC ECO:0000313|Proteomes:UP000002494}; RX PubMed=15057822; DOI=10.1038/nature02426; RG Rat Genome Sequencing Project Consortium; RA Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., RA Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., RA Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., RA Morgan M., Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., RA Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., RA Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., RA Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., RA Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., RA Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., RA Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., RA Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., RA Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., RA Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., RA Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., RA Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., RA D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., RA Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., RA Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., RA Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., RA Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., RA Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., RA Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., RA Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., RA Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., RA Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., RA Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., RA Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., RA Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., RA Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., RA Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., RA Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., RA Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., RA Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., RA Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., RA Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., RA Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., RA Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., RA Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., RA Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., RA Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., RA Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., RA Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., RA Collins F.S.; RT "Genome sequence of the Brown Norway rat yields insights into RT mammalian evolution."; RL Nature 428:493-521(2004). RN [2] {ECO:0000313|Ensembl:ENSRNOP00000050333} RP IDENTIFICATION. RC STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000050333}; RG Ensembl; RL Submitted (JUL-2011) to UniProtKB. CC -!- SUBCELLULAR LOCATION: Cell membrane CC {ECO:0000256|RuleBase:RU363047, ECO:0000256|SAAS:SAAS00857205}; CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU363047, CC ECO:0000256|SAAS:SAAS00857205}. CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family. CC {ECO:0000256|RuleBase:RU000688, ECO:0000256|SAAS:SAAS00857212}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC097089; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR RefSeq; NP_001000447.1; NM_001000447.1. DR UniGene; Rn.163012; -. DR ProteinModelPortal; D3ZCY9; -. DR STRING; 10116.ENSRNOP00000050333; -. DR PaxDb; D3ZCY9; -. DR Ensembl; ENSRNOT00000044223; ENSRNOP00000050333; ENSRNOG00000029086. DR GeneID; 300560; -. DR KEGG; rno:300560; -. DR UCSC; RGD:1333520; rat. DR CTD; 300560; -. DR RGD; 1334039; Olr1235. DR eggNOG; ENOG410IF93; Eukaryota. DR eggNOG; ENOG411183T; LUCA. DR GeneTree; ENSGT00900000140862; -. DR InParanoid; D3ZCY9; -. DR KO; K04257; -. DR OMA; MTRLFFF; -. DR OrthoDB; EOG091G0AZH; -. DR TreeFam; TF352753; -. DR Reactome; R-RNO-381753; Olfactory Signaling Pathway. DR Proteomes; UP000002494; Chromosome 4. DR Bgee; ENSRNOG00000029086; -. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. DR GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW. DR GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro. DR InterPro; IPR000276; GPCR_Rhodpsn. DR InterPro; IPR017452; GPCR_Rhodpsn_7TM. DR InterPro; IPR000725; Olfact_rcpt. DR Pfam; PF13853; 7tm_4; 1. DR PRINTS; PR00237; GPCRRHODOPSN. DR PRINTS; PR00245; OLFACTORYR. DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1. DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1. PE 3: Inferred from homology; KW Cell membrane {ECO:0000256|RuleBase:RU363047, KW ECO:0000256|SAAS:SAAS00857207}; KW Complete proteome {ECO:0000313|Proteomes:UP000002494}; KW G-protein coupled receptor {ECO:0000256|RuleBase:RU000688, KW ECO:0000256|SAAS:SAAS00857203}; KW Membrane {ECO:0000256|RuleBase:RU363047, KW ECO:0000256|SAAS:SAAS00857208}; KW Olfaction {ECO:0000256|RuleBase:RU363047, KW ECO:0000256|SAAS:SAAS00857209}; KW Receptor {ECO:0000256|RuleBase:RU000688, KW ECO:0000256|SAAS:SAAS00857193}; KW Reference proteome {ECO:0000313|Proteomes:UP000002494}; KW Sensory transduction {ECO:0000256|RuleBase:RU363047, KW ECO:0000256|SAAS:SAAS00857210}; KW Transducer {ECO:0000256|RuleBase:RU000688, KW ECO:0000256|SAAS:SAAS00857213}; KW Transmembrane {ECO:0000256|RuleBase:RU000688, KW ECO:0000256|SAAS:SAAS00857211}; KW Transmembrane helix {ECO:0000256|RuleBase:RU363047, KW ECO:0000256|SAAS:SAAS00857194}. FT TRANSMEM 27 48 Helical. {ECO:0000256|RuleBase:RU363047}. FT TRANSMEM 60 78 Helical. {ECO:0000256|RuleBase:RU363047}. FT TRANSMEM 98 120 Helical. {ECO:0000256|RuleBase:RU363047}. FT TRANSMEM 140 158 Helical. {ECO:0000256|RuleBase:RU363047}. FT TRANSMEM 197 225 Helical. {ECO:0000256|RuleBase:RU363047}. FT TRANSMEM 237 260 Helical. {ECO:0000256|RuleBase:RU363047}. FT TRANSMEM 272 291 Helical. {ECO:0000256|RuleBase:RU363047}. FT DOMAIN 41 289 G_PROTEIN_RECEP_F1_2. FT {ECO:0000259|PROSITE:PS50262}. SQ SEQUENCE 313 AA; 35013 MW; C5FFFC262D466D50 CRC64; MLAGNGSFVT EFVLAGLTDC PELQLPLFFL FLIIYIITVA GNIGLIILIG LNPHLHTPMY YFLFNLSFID LSYSSVFSPK MLMNFVSEKN SISFEGCMTQ LFLFLFFVIS ECYMLTSMAY DRYVAICNPL LYKVTMSPQV CSILSFAAYG MGFAGASVHT GCMLRLTFCN ANLINHYLCD ILPLLQLSCT STYVNEVVVL VVVGINITVP SCTILISYVF ILANILNIKS TQGRSKAFST CSSHIMAISL FFGSAAFMYL RYSSGSMEQG KISSVFYTNV GPMLNPLIYS LRNKDVKVAL RKSFIKFQRE YKF //